Results 51 to 60 of about 4,707 (174)

Improved speed and stability of st-segment recovery with reduced-dose tenecteplase and eptifibatide compared with full-dose tenecteplase for acute st-segment elevation myocardial infarction [PDF]

, 2004
ObjectivesThis sub-study of the Integrilin and Tenecteplase in Acute Myocardial Infarction (INTEGRITI) trial evaluated of the impact of combination reperfusion therapy with reduced-dose tenecteplase plus eptifibatide on continuous ST-segment recovery and
Giugliano, Robert P, Greenberg, Mark, Trollinger, Kathleen, Hannan, Karen, Harrington, Robert A, Gibson, C.Michael, Crater, Suzanne, Green, Cynthia L, Palmeri, Sebastian T, Baran, Kenneth, Krucoff, Mitchell W, Roe, Matthew T   +11 more
core   +1 more source

Off-target effects of thrombolytic drugs: apolipoprotein A-I proteolysis by alteplase and tenecteplase.

, 2013
The administration of thrombolytic drugs is of proven benefit in a variety of clinical conditions requiring acute revascularization, including acute myocardial infarction (AMI), ischemic stroke, pulmonary embolism, and venous thrombosis.
Pozzi S, SINAGRA, GIANFRANCO, Franceschini G, Vitali Serdoz L, Ossoli A, Gomaraschi M, Calabresi L., Vitali C, Pitzorno C   +8 more
core   +2 more sources

Thrombolytic therapy for patients with acute ischemic stroke: systematic review and network meta-analysis of randomized trials

Frontiers in Neurology
ObjectiveTo systematically compare the benefits and risks of all thrombolytic agents (tenecteplase, reteplase, and alteplase) at different doses for thrombolytic therapy in patients with acute ischemic stroke (AIS).BackgroundAlteplase is the cornerstone ...
Li-Chao-Yue Sun, Wen-Shu Li, Wei Chen, Zhao Ren, Chun-Xing Li, Ze Jiang, Le Wang, De-Li Wang, Qing Xie   +8 more
doaj   +1 more source

Successful use of Tenecteplase in a patient with recurrence of prosthetic mitral valve thrombosis

Indian Heart Journal, 2015
Introduction: Tenecteplase can be a more effective and convenient alternative in treatment of prosthetic valve thrombosis (PVT). Case: We hereby present a case of the use of Tenecteplase for recurrence of mitral valve thrombosis in a patient who was ...
Harshal A. Lahoti, Bal Krishna Goyal
doaj   +1 more source

Efficacy and Safety of Tirofiban for the Management of Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials (RCTs)

Brain and Behavior, Volume 16, Issue 6, June 2026.
Graphical representation of the comparative efficacy and safety of intravenous tirofiban for acute ischemic stroke in randomized controlled trials. ABSTRACT Background: Tirofiban is a GP IIb/IIIa inhibitor, an anti‐platelet drug that is used in ischemic stroke or acute coronary syndromes.
Dorothy Lim Bullecer, Cara Mohammed, Julie Anne De Lima Loiola, Mary Gabrielle Te Chy, Samratul Fuadah Ramli, Abimbola Sodiq Hussein, Wasid Bin Showkat, Thahsin Taikadan, Sarika Mutyala, Muhammad Ayyan, Muhammad Aemaz Ur Rehman, Adeel Ahmad, Asma'a Munasar Ali Alsubari   +12 more
wiley   +1 more source

Safety and efficacy comparison of Tenecteplase and Alteplase for clinically suspected large vessel occlusion strokes without thrombectomy

Cerebrovascular Diseases Extra
Introduction: Tenecteplase is a thrombolytic with higher fibrin affinity, and is potentially better in clot lysis. A higher spontaneous recanalization rate for large vessel occlusions strokes (LVO) had been shown in comparison studies with Alteplase ...
Wai Ting Lo, Wing Chi Fong, Chris Siu Kwan Chau, Moamina Ismail, Jessica Tsz Ching Li, Chong Ching Chan, Chi Him Simon Chan, Chung Yuen Chan, Germaine Hui-Fai Chan, Andrew Lung-Tat Chan, Man Sin Wong, Wai Yan Vivian Kwok, Hiu Fan Or, Shun Tim Chan, Ching Shing Fong, Nga Man Chan, Yuk Fai Cheung   +16 more
doaj   +1 more source

Pharmacokinetics and Neuroprotective Efficacy of Poly‐Arginine Peptide R18D in Sprague Dawley Rats Subjected to Transient Intraluminal Filament Middle Cerebral Artery Occlusion Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
The R18D peptide exhibits a favorable pharmacokinetic profile and significantly reduces infarct volume in a rat model of middle cerebral artery occlusion (MCAO) followed by reperfusion. These findings highlight the potential clinical utility of R18D as a neuroprotective therapy for stroke patients undergoing endovascular recanalization interventions ...
Bruno P. Meloni, Stuart K. Gribble, Meghan G. Thomas, Ayelet Weksler, Lena Finkelstein, Lena Fishtein, Dimitry Kovalchuk, Gilad Maximov, Avital Schauder, Keren Kigel‐Zur, Sigal Meilin   +10 more
wiley   +1 more source

Comparison of the safety and efficacy of dual antiplatelet therapy versus tenecteplase in patients with minor nondisabling acute ischemic stroke

Scientific Reports
To evaluate the safety and efficacy of dual antiplatelet therapy (DAPT) versus tenecteplase in minor non-disabling acute ischemic stroke. This retrospective observational study utilized data from our stroke database.
Xinzhao Jiang, Ruozhen Yuan, Jiawei Ye, Xu Wang, Zongjie Shi, Shunyuan Guo   +5 more
doaj   +1 more source

Reduced-Dose Tenecteplase in High-Risk Pulmonary Embolism

Background: Pulmonary embolism (PE) is a venous thromboembolic disease occurring when thrombi detach and embolize to pulmonary arteries, causing substantial morbidity and mortality in older adults yearly.
Cataldo, Dean, Kelly, Seth M., Allison, Christopher, MD, Hammond, Jennifer, MD   +3 more
core   +1 more source

Tenecteplase [PDF]

Reactions Weekly, 2020
  +4 more sources