Results 41 to 50 of about 3,406 (148)

Successful use of Tenecteplase in a patient with recurrence of prosthetic mitral valve thrombosis

Indian Heart Journal, 2015
Introduction: Tenecteplase can be a more effective and convenient alternative in treatment of prosthetic valve thrombosis (PVT). Case: We hereby present a case of the use of Tenecteplase for recurrence of mitral valve thrombosis in a patient who was ...
Harshal A. Lahoti, Bal Krishna Goyal
doaj   +1 more source

Cerebral Infarction: Epidemiology, Classification, Mechanisms, Diagnosis, and Management

MedComm, Volume 7, Issue 4, April 2026.
Within minutes after ischemia onset, deprivation of oxygen and glucose leads to rapid ATP depletion, resulting in failure of Na+/K+‐ATPase activity and membrane depolarization. This ionic imbalance promotes uncontrolled synaptic release of glutamate and excessive activation of postsynaptic NMDA and AMPA receptors.
Meibiao Zhang, Jianxun Hou, Jia Kuang, Lei Hao, Zhao Yang   +4 more
wiley   +1 more source

Successful use of intra venous tenecteplase for acute ischemic stroke in pregnancy

eNeurologicalSci
Intravenous thrombolysis (IVT) with tenecteplase or alteplase is the standard of care in, patients with Acute Ischemic Stroke (AIS) presenting within 3–4.5 h. However here, are no established guidelines for such treatment during pregnancy.
Balamurugan Namasivayam, Chitra Sengodan, Lavanya Mohanasundaram, Sathya Chinna Gounder, Madunisha Sivakumar   +4 more
doaj   +1 more source

Right Atrial Thrombus in Transit: A Case of Spontaneous Embolisation Captured Across Echocardiography

Respirology Case Reports, Volume 14, Issue 4, April 2026.
In this report, we describe a large RA thrombus in transit captured sequentially across multiple imaging modalities. This case highlights how quickly these thrombi can evolve and emphasises the need for individualised decision‐making when standard interventions are limited by clinical context.
Abdullah Al Qaraghuli, Sajjad Ghanim Al‐Badri, Mustafa Kadhim, Tala A. Haddad, Ronald Cadillo Hernandez, Sai Nitya Tejaswi Anne, Sashank Bollu, Ibrahim Khalil   +7 more
wiley   +1 more source

Comparison of the safety and efficacy of dual antiplatelet therapy versus tenecteplase in patients with minor nondisabling acute ischemic stroke

Scientific Reports
To evaluate the safety and efficacy of dual antiplatelet therapy (DAPT) versus tenecteplase in minor non-disabling acute ischemic stroke. This retrospective observational study utilized data from our stroke database.
Xinzhao Jiang, Ruozhen Yuan, Jiawei Ye, Xu Wang, Zongjie Shi, Shunyuan Guo   +5 more
doaj   +1 more source

Comment on: Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke—The 24‐h Time‐Point May be a Pro‐Thrombotic Blind Spot: Check 6‐h Fibrinogen Rebound to Catch Early Re‐Occluders

Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1299-1300, June 2026.
Qichao Fang, Luting Ying, Yongjin Gong
wiley   +1 more source

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

Annals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 574-580, March 2026.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani, Dylan N. Wolman, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Kelsey E. Kline, Clemens M. Schirmer, Raul G. Nogueira, Alexandra R. Paul, Bradley N. Bohnstedt, Philipp Hendrix   +38 more
wiley   +1 more source

Outcomes associated to the time to treatment with intravenous tenecteplase for acute ischaemic stroke: subgroup analysis of the TRACE-2 randomised controlled clinical trial

Stroke and Vascular Neurology
Background The benefit of intravenous alteplase in acute ischaemic stroke (AIS) is time-dependent. Tenecteplase is non-inferior to alteplase among patients with AIS.
Bruce C V Campbell, Yongjun Wang, Yilong Wang, Zixiao Li, Xingquan Zhao, David Wang, Yunyun Xiong, Hao Li, Xia Meng, Yuesong Pan, Lee H Schwamm, Aoming Jin, Mark W Parsons, Huaguang Zheng, Shuya Li, Runhui Li, Marc Fisher, Runqi Wangqin, Ziran Wang, Deyang Li, Hongguo Dai, Junhai Wang   +21 more
doaj   +1 more source

Tenecteplase [PDF]

Reactions Weekly, 2020
  +4 more sources

Implementation of a Tenecteplase Protocol for Treatment of Acute Ischemic Stroke in a Health System

INNOVATIONS in Pharmacy
Purpose. Alteplase is the standard of care for intravenous thrombolytic treatment of acute ischemic stroke, but recent evidence suggests that tenecteplase may be as safe and efficacious. The purpose of this study was to evaluate the direct cost savings,
Alexis Pace, Maya Wai, Ethan Frye
doaj