Results 21 to 30 of about 4,707 (174)

Tenecteplase versus alteplase before thrombectomy for ischemic stroke [PDF]

, 2018
BACKGROUND: Intravenous infusion of alteplase is used for thrombolysis before endovascular thrombectomy for ischemic stroke. Tenecteplase, which is more fibrin-specific and has longer activity than alteplase, is given as a bolus and may increase the ...
Mitchell, P., Ang, T., Kleinig, T., Dewey, H., Bush, S., Shah, D., Churilov, L., Asadi, H., Simpson, M., Thijs, V., Levi, C., Miteff, F., Campbell, B., Brooks, M., Yan, B., Scroop, R., Wu, T., Yassi, N., Dowling, R., Wijeratne, T., et al.   +20 more
core   +4 more sources

Comparative Effectiveness of Intravenous Tenecteplase versus Alteplase in Posterior Circulation Ischemic Stroke: A Systematic Review and Meta‐Analysis [PDF]

Brain Behav
Visual summary of the comparative efficacy and safety of intravenous tenecteplase versus alteplase in posterior circulation ischemic stroke. ABSTRACT Background Posterior circulation ischemic stroke (PCIS) is associated with substantial morbidity and mortality, and the optimal intravenous thrombolytic strategy in this subgroup remains unclear.
Shafiq S, Uddin A, Hussain M, Khan G, Hassan M, Razzak M, Majid M, Islam F, Ahmed U, Uddin A, Aminpoor H, Ahmed M.   +11 more
europepmc   +2 more sources

Where Evidence-Based Medicine Meets AI: Promise, Pitfalls, and Practice. [PDF]

AEM Educ Train
AEM Education and Training, Volume 10, Issue 3, June 2026.
Lee S, Davis J, Milne K, Shenvi C, Beattie LK, Wegman M, Melville L, Shih RD, Kane B.   +8 more
europepmc   +2 more sources

Safety and Outcomes of Tenecteplase in Moderate and Severe Ischemic Stroke. Results From NOR-TEST [PDF]

, 2019
Background and Purpose — Tenecteplase represents a promising alternative to alteplase as thrombolytic treatment in acute ischemic stroke. There are limited data on tenecteplase 0.4 mg/kg in patients with increased stroke severity.
Logallo, Nicola, Waje-Andreassen, Ulrike, Næss, Halvor, Kvistad, Christopher Elnan, Carlsson, Maria, Rønning, Ole M., Thomassen, Lars, Novotny, Vojtech, Kurz, Martin, Thommessen, Bente   +9 more
core   +1 more source

Studi literatur efektivitas dan keamanan tenecteplase pada pasien stroke iskemik [PDF]

, 2021
Stroke iskemik adalah hilangnya fungsi otak secara tiba-tiba akibat terganggunya suplai darah ke bagian otak. Salah satu tatalaksana pengobatan stroke iskemik adalah obat golongan fibrinolitik yang berkerja memecah trombus dengan mengaktivasi plasminogen
Nutrianti, Havis
core  

Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion

, 2021
Intrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase.
Husain Kadhem, Kannan Sridharan, Naser Naser   +2 more
core   +1 more source

Tenecteplase in prosthetic mitral valve thrombosis [PDF]

, 2011
In the few reported cases of prosthetic mitral valve thrombosis, where surgical intervention was considered as high risk, fibrinolytic therapy had proved life saving.
Norbert Augustin, Sherif Bakir, Al Nassir, Adnan, Bakir, Sherif, Turrin, Nicolas Patrick, Al Zubaidi, Abdulmajeed, Ayyub Ghori, Masood, Augustin, Norbert, Masood Ayyub Ghori, Samer Ellahham, Abdulmajeed Al Zubaidi, Ellahham, Samer, Wael Abdulrahman Al Mahmeed, Abdelaziz, Moataz Ayman, Adnan Al Nassir, Al Mahmeed, Wael Abdulrahman, Moataz Ayman Abdelaziz, Nicolas Patrick Turrin   +17 more
core   +1 more source

Tenecteplase versus alteplase for the treatment of acute ischemic stroke: a meta-analysis of randomized controlled trials

Annals of Medicine
Objectives Tenecteplase, a modified variant of alteplase with greater fibrin specificity and longer plasma half-life, may have better efficacy and safety than alteplase in patients with acute ischemic stroke (AIS).
Jian Huang, Hui Zheng, Xianfeng Zhu, Kai Zhang, Xiaofeng Ping   +4 more
doaj   +1 more source

Intravenous Tenecteplase before Thrombectomy in Stroke [PDF]

BACKGROUND: The safety and efficacy of treatment with intravenous tenecteplase before endovascular thrombectomy in patients with acute ischemic stroke due to large-vessel occlusion remain uncertain.
Luo, X., Li, Q., Kong, Z., Investigators, Bridge-Tnk Trial, Nguyen, T. N., Li, Y., Zi, W., Zeng, G., Huang, X., Yuan, G., Tian, Y., Campbell, B. C. V., Zhao, M., Liu, J., Li, M., Jiang, S., Lei, B., Cai, L., Jiang, L., Xie, D., Wu, D., Zhou, P., Yin, C., Liu, W., Yang, Q., Lu, M., Liu, S., Sang, H., Li, F., Wang, D., Chang, M., Zhao, H., Xia, Z., Long, X., Yi, T., Albers, G. W., Zhou, K., Wu, Youlin, Qiu, Z., Luo, J., Dai, H., Li, C., Tao, J., Song, D., Ruan, Z., Zheng, C., Peng, Y., Saver, J. L., You, F., Hu, H., Shi, Z., Yang, G., Wu, J., Zhou, J., Nogueira, R. G., Jiang, B., Tian, Z., Long, C., Yang, B., Tang, Y., Li, H., Meng, Z., Yan, Z., Feng, X., Tan, X., Li, L.   +65 more
core   +1 more source

Cost-effectiveness of tenecteplase before thrombectomy for ischemic stroke

, 2020
BACKGROUND AND PURPOSE: Tenecteplase improved functional outcomes and reduced the requirement for endovascular thrombectomy in ischemic stroke patients with large vessel occlusion in the EXTEND-IA TNK randomized trial.
Parsons, M.W., Yan, B., Davis, S.M., Yassi, N., Mitchell, P.J., Churilov, L., Donnan, G.A., Gao, L., Kleinig, T.J., EXTEND-IA TNK Investigators,, Moodie, M., Campbell, B.C.V.   +11 more
core   +2 more sources