Results 21 to 30 of about 519,002 (319)

An automatic visual analysis system for tennis [PDF]

, 2013
This article presents a novel video analysis system for coaching tennis players of all levels, which uses computer vision algorithms to automatically edit and index tennis videos into meaningful annotations.
Chin JP, Conaire CO, Connaghan D, Franks M, Heckerman D., Horprasert T, Ke K, O’Donoghue P, Petkovic M, Yamagiwa S   +9 more
core   +1 more source

Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice

Neurobiology of Disease, 2009
Huntington's disease (HD) is caused by an expanded CAG repeat in the HD gene. The pathological threshold for expansion in HD is around 36 CAG repeats, although ‘super-long’ expansions are found in brains of HD patients.
A Jennifer Morton, Dervila Glynn, Wendy Leavens, Zhiguang Zheng, Richard L.M. Faull, Jeremy N. Skepper, James M. Wight   +6 more
doaj   +1 more source

DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation

Viruses, 2022
The transcription factors IRF3 and NF-κB are crucial in innate immune signalling in response to many viral and bacterial pathogens. However, mechanisms leading to their activation remain incompletely understood. Viral RNA can be detected by RLR receptors,
Mitchell A. Pallett, Yongxu Lu, Geoffrey L. Smith   +2 more
doaj   +1 more source

Cyclic AMP Recruits a Discrete Intracellular Ca2+ Store by Unmasking Hypersensitive IP3 Receptors

Cell Reports, 2017
Inositol 1,4,5-trisphosphate (IP3) stimulates Ca2+ release from the endoplasmic reticulum (ER), and the response is potentiated by 3′,5′-cyclic AMP (cAMP).
Vera Konieczny, Stephen C. Tovey, Stefania Mataragka, David L. Prole, Colin W. Taylor   +4 more
doaj   +1 more source

Residues in the 1st Transmembrane-Spanning Helix Are Important for GABA_Aρ Receptor Function

Biomolecules, 2022
GABAAρ receptors are a subfamily of the GABAA receptor family of pentameric ligand-gated ion channels (pLGICs). Each subunit has a common structure, including a transmembrane domain of four α-helices (M1–M4).
Kate M. Crowther, Susanne M. Mesoy, Sarah C. R. Lummis   +2 more
doaj   +1 more source

Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining

Journal of Nucleic Acids, 2010
Nonhomologous end joining (NHEJ) plays a major role in double-strand break DNA repair, which involves a series of steps mediated by multiprotein complexes.
Takashi Ochi, Bancinyane Lynn Sibanda, Qian Wu, Dimitri Y. Chirgadze, Victor M. Bolanos-Garcia, Tom L. Blundell   +5 more
doaj   +1 more source

IP3 Receptors Preferentially Associate with ER-Lysosome Contact Sites and Selectively Deliver Ca2+ to Lysosomes

Cell Reports, 2018
Summary: Inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) allow extracellular stimuli to redistribute Ca2+ from the ER to cytosol or other organelles.
Peace Atakpa, Nagendra Babu Thillaiappan, Stefania Mataragka, David L. Prole, Colin W. Taylor   +4 more
doaj   +1 more source

The MA Helix Is Important for Receptor Assembly and Function in the α4β2 nACh Receptor

Membranes, 2023
Pentameric ligand-gated ion channels (pLGICs) are expressed throughout the central and peripheral nervous systems of vertebrates and modulate many aspects of human health and disease.
Dorottya I. Fricska, Susanne M. Mesoy, Sarah C. R. Lummis   +2 more
doaj   +1 more source

Effects of intervention upon precompetition state anxiety in elite junior tennis players: The relevance of the matching hypothesis [PDF]

, 1995
Reproduced with permission of publisher from: Terry, P., Coakley, L., & Karageorghis, C. Effects of intervention upon precompetition state anxiety in elite junior tennis players: the relevance of the matching hypothesis.
Burton D., Costas Karageorghis, Davidson R. J., Edwards T., Harris D. V., Jones J. G., Lisa Coakley, Martens R., Nideffer R., Ost L. G., Peter Terry, Suinn R. M., Syer J.   +12 more
core   +1 more source

RNA modifications detection by comparative Nanopore direct RNA sequencing

Nature Communications, 2021
Nanopore direct RNA Sequencing data contain information about the presence of RNA modifications, but their detection poses substantial challenges. Here the authors introduce Nanocompore, a new methodology for modification detection from Nanopore data.
Adrien Leger, Paulo P. Amaral, Luca Pandolfini, Charlotte Capitanchik, Federica Capraro, Valentina Miano, Valentina Migliori, Patrick Toolan-Kerr, Theodora Sideri, Anton J. Enright, Konstantinos Tzelepis, Folkert J. van Werven, Nicholas M. Luscombe, Isaia Barbieri, Jernej Ule, Tomas Fitzgerald, Ewan Birney, Tommaso Leonardi, Tony Kouzarides   +18 more
doaj   +1 more source