Results 31 to 40 of about 34,537 (182)
Viruses, 2022 My collaboration with Prof. Antonín Holý, that spans a period of 3–4 decades (1976–2012), led to the discovery of several acyclic nucleoside phosphonates (ANPs) which were clinically developed by Gilead Sciences: cidofovir, adefovir, and tenofovir.
Erik De Clercq
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Acta Obstetricia et Gynecologica Scandinavica, EarlyView.In women living with HIV, HPV clearance occurred after a mean of approximately 2 years under antiretroviral therapy. Baseline positivity for the high‐risk HPV pool was associated with delayed clearance, suggesting that HPV genotype may influence viral persistence more than immunovirological status in clinically stable patients.
Annunziata Carlea +10 more
wiley +1 more source
Targeted Immuno-Antiretroviral to Promote Dual Protection against HIV: A Proof-of-Concept Study
Nanomaterials, 2022 The C–C motif chemokine receptor-5 (CCR5) expression on the T-cell surface is the prime barrier to HIV/AIDS eradication, as it promotes both active human immunodeficiency virus (HIV)-infection and latency; however, antiretrovirals (ARVs) suppress plasma ...
Subhra Mandal +5 more
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Alimentary Pharmacology &Therapeutics, EarlyView.In 902 patients with HBV‐related HCC undergoing curative resection, antiviral regimens (ETV, TDF, TAF) showed comparable recurrence‐free survival. However, TDF was independently associated with improved overall survival compared with ETV. ABSTRACT Background & Aims The comparative outcomes of entecavir (ETV), tenofovir disoproxil fumarate (TDF), and ...
Jaehong Jeong +10 more
wiley +1 more source
Jurnal Kesehatan Andalas, 2014 AbstrakPenyakit ginjal merupakan penyebab kematian nonAIDS paling tinggi pada penyandang HIV. Penggunaan regimen anti- retroviral diselidiki memiliki kontribusi terhadap kejadian penyakit ginjal.
Regina Ivanovna, Efrida ., Roza Kurniati
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Pharmaceutics, 2022 Nucleos(t)ide reverse transcriptase inhibitors (NRTIs) are the backbone of HIV antiretroviral therapy (ART). ART use in pregnancy has been associated with adverse birth outcomes, in part due to NRTI-induced mitochondrial toxicity.
Kayode Balogun, Lena Serghides
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Why Engage Communities in Biomedical Research?
Bioethics, EarlyView.ABSTRACT While community engagement in biomedical research is widely lauded, and many reasons to engage communities have been adduced, it is unclear whether all these reasons are equally important, and, if not, which are most important. Here, I argue that, outside of rare circumstances, community engagement should not be understood as seeking ...
Robert Steel
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HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann +7 more
wiley +1 more source
The Saudi Journal of Gastroenterology, 2017 Background/Aims: The ideal end point of treatment for chronic hepatitis B virus (HBV) infection is sustained off-therapy hepatitis B surface antigen (HBsAg) loss with or even without seroconversion to anti-HBs.
Hamad Al Ashgar +9 more
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Co-crystals, Salts or Mixtures of Both? The Case of Tenofovir Alafenamide Fumarates
Pharmaceutics, 2020 Tenofovir alafenamide fumarate (TAF) is the newest prodrug of tenofovir that constitutes several drug products used for the treatment of HIV/AIDS. Although the solid-state properties of its predecessor tenofovir disoproxil fumarate have been investigated
Hannes Lengauer +7 more
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