Results 51 to 60 of about 5,741,783 (179)

Tenosynovial giant cell tumor of the ankle: a clinical case

Acta Biomedica Scientifica
Background. Tenosynovial giant cell tumor is a rare benign disease that primarily affects the synovium and tendon sheath. Its prevalence is 30.3 cases per million people per year.
I. A. Kuklin, D. V. Menshova, I. V. Usoltsev, N. V. Tishkov, E. E. Chepurnykh   +4 more
doaj   +1 more source

Expanding the molecular spectrum of tenosynovial giant cell tumors

Frontiers in Oncology, 2022
BackgroundWhile great advances in clinical and pathological description of tenosynovial giant cell tumors (TGCT) have been made, TGCT molecular heterogeneity represents an ongoing challenge. The canonical oncogenic fusion CSF1::COL6A3 is not systematically observed, suggesting that other oncogenic mechanisms are involved in tumorigenesis.
Thibault Gauduchon, Helene Vanacker, Helene Vanacker, Daniel Pissaloux, Philippe Cassier, Armelle Dufresne, Marie Karanian, Alexandra Meurgey, Amine Bouhamama, François Gouin, Isabelle Ray-Coquard, Isabelle Ray-Coquard, Jean-Yves Blay, Jean-Yves Blay, Franck Tirode, Mehdi Brahmi, Mehdi Brahmi   +16 more
openaire   +4 more sources

Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis [PDF]

, 2015
Tenosynovial giant cell tumour, diffuse type, also known under a variety of other terms including diffuse pigmented villonodular synovitis, tends to be locally aggressive and not infrequently can show multiple recurrences. The differential diagnosis with
Dei Tos A.P., Righi, A, Donati, D, Gambarotti, M, Vanel, D, Sbaraglia M, Donati D, Frisoni, T, Vanel D, Gambarotti M, Righi A, Dei Tos, A P, Sbaraglia, M, Frisoni T   +13 more
core   +1 more source

Management of Tenosynovial Giant Cell Tumor: A Neoplastic and Inflammatory Disease [PDF]

, 2020
BackgroundPatients with diffuse tenosynovial giant cell tumor (TGCT) face a high risk of recurrence, progression, and disability. This systematic review assesses the recent evidence of surgical, adjuvant, and systemic treatments for TGCT.MethodsWe ...
Bernthal, Nicholas M, van de Sande, Michiel, Healey, John H   +2 more
core   +1 more source

Fat‐Containing Soft Tissue Lesions of the Limbs and Body Wall—A Pictorial Essay

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Lipomatous tumours are frequently encountered on imaging. The spectrum of lipomatous tumours ranges from simple lipomas, which can be monitored clinically, to high‐grade liposarcomas, which require timely, multidisciplinary management. The presence of fat within lesions may also be observed in non‐lipomatous tumours, as well as in a variety of
Kai‐Zheong Lim, Cathryn Hui
wiley   +1 more source

Pigmented villonodular synovitis of the temporomandibular joint and skull base

Otolaryngology Case Reports, 2021
Pigmented villonodular synovitis (PVNS) is a diffuse type tenosynovial giant cell tumor, which are benign but locally aggressive tumors presenting in joint, tendon sheath, and bursa synovium. This tumor most commonly occurs in the knee; it is rare in the
Dorothy W. Pan, Sunitha Husson, John S. Oghalai   +2 more
doaj   +1 more source

UTMD Suppresses CSF‐1 to Drive Macrophage‐Mediated Ferroptosis in Papillary Thyroid Carcinoma

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT The tumor microenvironment (TME) of Papillary Thyroid Carcinoma (PTC), particularly the role of tumor‐associated macrophages (TAMs), contributes to therapeutic resistance. This study investigated whether ultrasound‐targeted microbubble destruction (UTMD), a non‐invasive physical modality, could reprogram the TME through modulation of TAMs and ...
Yanqiang Niu, Zhenqiang Yao, Minghua Zhang, Jiayan Zhang, Yushan Li, Jinhui Xie, Zubang Zhou   +6 more
wiley   +1 more source

Optimal Treatment for Tenosynovial Giant Cell Tumor of the Hand

Journal of Nippon Medical School, 2020
This review examines the following aspects of tenosynovial giant cell tumors (TSGCTs): the use of multiple names, the complex relationship between tumor growth pattern and location, the high rate of postoperative recurrence, local invasiveness, use of nonsurgical therapy with molecularly targeted drugs, and best current treatments.
Kitagawa, Yasuyuki, Takai, Shinro
openaire   +3 more sources

Tenosynovial Giant Cell Tumors in the Hand and Foot

Cureus
Giant cell tumor of the tendon sheath (GCTTS) is one of the most common benign, slow-growing soft tissue tumors of the hand and foot. This study aimed to evaluate the anatomic distribution of the GCTTS and correlate the surgical treatment with clinical outcomes and recurrence rates.In this retrospective study, a total of 78 cases of GCTTS of the hand ...
Stefanou, Nikolaos, Varitimidis, Sokratis, Samaila, Elena Manuela, Koutis, Athanasios, Karachalios, Theofilos, Dailiana, Zoe   +5 more
openaire   +2 more sources

Tissue‐Resident Macrophage in Inflammation and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang, Jiangbo Fan, Wenyi Liu, Di Liu, Rui Wang, Yuanyang Wang, Jianhui Sun, Huacai Zhang, Qingli Cai, Zhe Xu, Fang Xu, Jianxin Jiang, Zhen Wang, Ling Zeng   +13 more
wiley   +1 more source