Results 11 to 20 of about 5,762,549 (184)

The diffuse-type tenosynovial giant cell tumor (dt-TGCT) patient journey: a prospective multicenter study [PDF]

Orphanet Journal of Rare Diseases, 2021
Background Tenosynovial giant cell tumor (TGCT) is a rare, locally aggressive neoplasm arising from the synovium of joints, bursae, and tendon sheaths affecting small and large joints.
Nicholas M. Bernthal, Geert Spierenburg, John H. Healey, Emanuela Palmerini, Sebastian Bauer, TOPP Study Group, Hans Gelderblom, Eric L. Staals, Julio Lopez-Bastida, Eva-Maria Fronk, Xin Ye, Petra Laeis, Michiel A. J. van de Sande   +12 more
doaj   +11 more sources

Recurrent Tenosynovial Giant Cell Tumor (TGCT) in Thumb Treated by Excision and Adjuvant 3DCRT Radiation. [PDF]

Indian J Orthop, 2022
Tenosynovial giant cell tumors (TGCT) are benign intra-articular and soft-tissue tumors. However, they are known for recurrence in incomplete excisions and tumors adjacent to the distal joints and neurovascular structures in hand. With poor knowledge of intrinsic biology behind these clonal neoplastic tumors, wide excision and three-dimensional ...
Jerome JTJ, Sofia LR, Santhi N.
europepmc   +4 more sources

Updates on the Treatment of Tenosynovial Giant Cell Tumor

Hematology/Oncology and Stem Cell Therapy, 2023
Tenosynovial giant cell tumor (TGCT) is a rare inflammatory disorder affecting the joint synovium, bursae, and tendon sheaths that causes non-specific and often insidious joint discomfort.
Abigail S. Chan, Vatsala Katiyar, Paul Dy, Vikas Singh   +3 more
doaj   +2 more sources

MRI Radiomics for Predicting the Diffuse Type of Tenosynovial Giant Cell Tumor: An Exploratory Study [PDF]

Diagnostics
Objective: To develop and validate a radiomics-based MRI model for prediction of diffuse-type tenosynovial giant cell tumor (D-TGCT), which has higher postoperative recurrence and more aggressive behavior than localized-type (L-TGCT).
Seul Ki Lee, Min Wook Joo, Jee-Young Kim, Mingeon Kim   +3 more
doaj   +3 more sources

Hot shoulder PET/CT lesion: Unusual presentation of tenosynovial giant cell tumor

Radiology Case Reports, 2018
We present a case of a tenosynovial giant cell tumor (TGCT) incidentally discovered at the shoulder on PET/CT, in a patient with history of thyroid cancer.
Steven Lewis, MD, Lance Edmonds, MD, Ely Wolin, MD   +2 more
doaj   +2 more sources

Overview of Pharmacological Therapies for Diffuse Tenosynovial Giant Cell Tumor

Future Pharmacology, 2023
Tenosynovial giant cell tumor (TGCT) is a rare and locally aggressive benign tumor arising from the synovium of joints, bursae, and tendon sheaths. It is classified into localized (L-TGCT) and diffuse (D-TGCT) forms based on the extent of involvement ...
Antonia Stamatiou, Tu Nguyen-Ngoc, Laureline Wetterwald, Ana-Maria Dolcan, Giovanni Dei Tos, Stephane Cherix, Patrick Omoumi, Antonia Digklia   +7 more
doaj   +2 more sources

Fine needle aspiration cytology diagnosis of metastatic malignant diffuse type tenosynovial giant cell tumor

Journal of Cytology, 2017
Tenosynovial giant cell tumors (TGCTs) arise from the synovium of joint, bursa, and tendon sheath, and are classified into localized and diffuse types.
Prashant Ramteke, Venkat K Iyer, Karan Madan, Shivanand Gamangatti, Asit R Mridha   +4 more
doaj   +2 more sources

Localized Tenosynovial Giant Cell Tumor After Total Knee Arthroplasty

Arthroplasty Today
Tenosynovial giant cell tumor (TGCT) occurs in both diffuse and localized forms. While diffuse TGCT is an uncommon but well-described complication after total knee arthroplasty (TKA), localized TGCT has only once been previously described as a ...
Nicket Dedhia, MD, Diego Zamata-Ovalle, BS, Emma Johnson, MD, Evan Schwechter, MD   +3 more
doaj   +2 more sources

Tenosynovial giant cell tumor presenting as a parotid gland mass: Expanding the differential diagnosis of giant cell-rich lesions in salivary glands

Journal of Cytology, 2014
Tenosynovial giant cell tumors (TGCT) are rare benign soft tissue tumors affecting mostly young adults. The most common affected sites include the knee, ankle, elbow, shoulder, and fingers. The temporomandibular joint is occasionally affected. Herein, we
Ling Guo, Shadi Qasem, Simon Bergman, Ziyan T Salih   +3 more
doaj   +2 more sources

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

Advanced Science
Diffuse‐type tenosynovial giant cell tumor (D‐TGCT) and localized‐type tenosynovial giant cell tumor (L‐TGCT) share common genomic aberrations and histopathological features, but the former has a more aggressive nature and a higher recurrence rate ...
Yubin Xie, Chen Chen, Fei Wu, Yiman Peng, Jing Su, Yang Zhao, Hongjie Huang, Zhong Alan Li, Yin Pei, Wencui Li, Yi He, Tianchen Xue, Chenxi Cao, Sui Peng, Xin Zhang, Weidong Song   +15 more
doaj   +2 more sources