Results 1 to 10 of about 8,934 (195)

Treatment Modalities for Refractory-Recurrent Tenosynovial Giant Cell Tumor (TGCT): An Update

Medicina (Lithuania)
Background and Objectives: Tenosynovial giant cell tumor (TGCT) is a rare, locally aggressive, benign neoplasm arising from the synovium of joints, tendon sheaths, and bursa.
Nikolaos Stavropoulos, Olga D Savvidou, Panagiotis Koulouvaris   +2 more
exaly   +8 more sources

Pediatric patients with tenosynovial giant cell tumor: real-world evidence from an observational registry [PDF]

Orphanet Journal of Rare Diseases
Background Tenosynovial giant cell tumor (TGCT) is a rare, locally aggressive tumor originating in the synovial lining of the joint, bursa, and tendon sheath.
Sydney Stern, Patrick F. McKenzie, Giacomo G. Baldi, Thomas J. Scharschmidt, Emanuela Palmerini, Sara Rothschild   +5 more
doaj   +2 more sources

Optimal clinical management of tenosynovial giant cell tumours: a UK perspective [PDF]

Bone & Joint Open
Aims: Tenosynovial giant cell tumour (TGCT) management is variable across the UK. Our aim was to examine these differences in clinical practice and develop consensus statements regarding the management of TGCTs.
The TGCT UK Consortium
doaj   +2 more sources

A New Simple and Practical Clinical Classification for Tenosynovial Giant Cell Tumors of the Knee

Orthopaedic Surgery, 2022
Objective To propose a simple and practical clinical classification for tenosynovial giant cell tumor (TGCT) of the knee. Methods A retrospective study was conducted to verify the value and significance of this clinical classification.
Kai Zheng, Xiu‐chun Yu, Yong‐cheng Hu, Ming Xu, Jing‐yu Zhang   +4 more
doaj   +1 more source

Impact of testicular cancer on sperm small non-coding RNA signature: a pilot study

Epigenetics, 2023
Testicular germ cell tumours (TGCTs) are the most common tumours in young adults of European ancestry. The high heritability and the constantly increased incidence, which has doubled over the last 20 years, strongly suggest that both genetic and ...
Charlotte Dupont, Maria G. Stathopoulou, Pierre-Julien Illy, Nathalie Sermondade, Rachel Levy, Michele Trabucchi, Marie Prades, Rahaf Haj Hamid, Isabelle Berthaut, Valérie Grandjean   +9 more
doaj   +1 more source

Long Non-Coding RNA RFPL3S Functions as a Biomarker of Prognostic and Immunotherapeutic Prediction in Testicular Germ Cell Tumor

Frontiers in Immunology, 2022
The incidence of testicular germ cell tumor (TGCT) is currently on the rise worldwide, of which 15%-30% of patients have occur recurrence and metastasis. However, clinical methods for diagnosing TGCT and judging its prognosis remained inadequate. In this
Jie Guo, Jie Guo, Shuang Wang, Zhenzhen Jiang, Le Tang, Zhizhong Liu, Jian Cao, Zhaolan Hu, Xiao Chen, Yanwei Luo, Hao Bo, Hao Bo   +11 more
doaj   +1 more source

Integrated analysis of high-throughput sequencing data reveals the key role of LINC00467 in the invasion and metastasis of testicular germ cell tumors

Cell Death Discovery, 2021
Long noncoding RNAs (lncRNAs) are involved in various physiological and pathological processes. However, the role of lncRNAs in testicular germ cell tumor (TGCT) has been rarely reported.
Hao Bo, Fang Zhu, Zhizhong Liu, Qi Deng, Guangmin Liu, Ruixue Li, Wenbing Zhu, Yueqiu Tan, Gang Liu, Jingyu Fan, Liqing Fan   +10 more
doaj   +1 more source

Testis-expressed gene 11 inhibits cisplatin-induced DNA damage and contributes to chemoresistance in testicular germ cell tumor

Scientific Reports, 2022
Testicular germ cell tumor (TGCT) is a rare cancer but the most common tumor among adolescent and young adult males. Patients with advanced TGCT often exhibit a worse prognosis due to the acquisition of therapeutic resistance.
Sachi Kitayama, Kazuhiro Ikeda, Wataru Sato, Hideki Takeshita, Satoru Kawakami, Satoshi Inoue, Kuniko Horie   +6 more
doaj   +1 more source

Overview of Pharmacological Therapies for Diffuse Tenosynovial Giant Cell Tumor

Future Pharmacology, 2023
Tenosynovial giant cell tumor (TGCT) is a rare and locally aggressive benign tumor arising from the synovium of joints, bursae, and tendon sheaths. It is classified into localized (L-TGCT) and diffuse (D-TGCT) forms based on the extent of involvement ...
Antonia Stamatiou, Tu Nguyen-Ngoc, Laureline Wetterwald, Ana-Maria Dolcan, Giovanni Dei Tos, Stephane Cherix, Patrick Omoumi, Antonia Digklia   +7 more
doaj   +1 more source

Diffuse-Type Tenosynovial Giant Cell Tumor of the Knee with Concurrent Polymicrobial Infection (Klebsiella oxytoca and Group B Streptococcus)

Case Reports in Infectious Diseases, 2021
Tenosynovial giant cell tumors (TGCT) are a rare class of benign proliferative tumors that are classified according to their presentation: localized-type (L-TGCT) or diffuse-type (D-TGCT).
J. Hunter Marshall, John G. Skedros, Chris F. Campana, Allan M. Seibert   +3 more
doaj   +1 more source