ApoE-expressing astrocytes physically interact with injury-induced GFP-expressing dendrites.
(A) Representative section of the contralateral and ipsilateral cortex and hippocampus 4 weeks after Controlled Cortical Impact and stereotaxic injection of GFP-expressing retroviruses in the dentate gyrus of a wildtype mouse reveals the typical ...
Tzong-Shiue Yu (695757) +2 more
core +1 more source
eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice. [PDF]
All three nitric oxide synthase (NOS) isoforms are expressed in atherosclerotic plaques. NOS enzymes in general catalyse NO production. However, under conditions of substrate and cofactor deficiency, the enzyme directly catalyse superoxide formation ...
Sabine Grüner +27 more
core +2 more sources
APOE-independent dEQ biomarkers (unrelated to APOE by Path c).
APOE-independent dEQ biomarkers (unrelated to APOE by Path c).
Ram Bishnoi (3836311) +3 more
core +1 more source
ApoE gene therapy to treat hyperlipidemia and atherosclerosis [PDF]
Atherosclerosis is the leading cause of death in industrialized countries and is becoming an increasingly worldwide risk to health. Apolipoprotein E (ApoE) is a blood circulating protein with pleiotropic atheroprotective properties that has emerged as a ...
Owen, JS +3 more
core
Retardation of atherosclerosis in immunocompetent apolipoprotein (apo) E-deficient mice followingliver-directed administration of a [E1-, E3-,polymerase-] adenovirus vector containing the elongation factor-1a promoter driving expression of human apoE cDNA [PDF]
Although gene transfer of human apolipoprotein E (apoE), a 34-kDa circulating glycoprotein, to the liver of apoEdeficient(apoE-/-) mice using recombinant adenoviral vectors (rAd) is antiatherogenic, its full therapeutic potentialhas yet to be realized ...
Stannard, AK +6 more
core
¿Cómo impacta el conocimiento que tiene un profesor acerca de la teoría APOE sobre su conocimiento especializado? [PDF]
"En este trabajo de investigación se explora, a partir del análisis de dos trabajos de grado de maestría, la influencia que tiene el conocimiento de una teoría institucionalizada de la educación matemática sobre el resto del conocimiento especializado ...
Sanchez Garcia, Jose Antonio +1 more
core
Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A +4 more
core
APOE genotype and entorhinal cortex volume in non-demented community-dwelling adults in midlife and early old age [PDF]
Copyright © 2012 IOS PressThis article has been made available through the Brunel Open Access Publishing Fund.The apolipoprotein E (APOE) ε4 allele is a risk factor for the neuropathological decline accompanying Alzheimer's disease (AD) while, conversely,
Bunce, David +17 more
core +1 more source
Análisis de actividades didácticas para el estudio del límite de una función por medio de la teoría APOE [PDF]
En este trabajo se presenta el análisis de un conjunto de actividades relacionadas con el concepto de límite de una función desde la perspectiva de la Teoría APOE.
Guerrero, Jose Javier +1 more
core
Esta investigación propone y valida empíricamente una descomposición genética, basada en la teoría APOE, para el aprendizaje del concepto de derivación implícita. Se analiza el impacto de una intervención didáctica, diseñada a partir de la descomposición
Claudio Fuentealba, Andrea Cárcamo
doaj +1 more source

