Inflammatory pathways and anti‐inflammatory therapies in sickle cell disease
Abstract Sickle cell disease (SCD) is a monogenic disease, resulting from a single‐point mutation, that presents a complex pathophysiology and high clinical heterogeneity. Inflammation stands as a prominent characteristic of SCD. Over the past few decades, the role of different cells and molecules in the regulation of the inflammatory process has been ...
Karina Tozatto‐Maio +3 more
wiley +1 more source
Terapia génica: ¿Qué es y para qué sirve? [PDF]
Gene therapy has developed as a method of approach to the treatment of human diseases based on the transfer of genetic material to the cells of an individual.
Ruiz-Castellanos, M. (M.) +1 more
core +1 more source
Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. VI: Accreditation process. [PDF]
De Santis GC +9 more
europepmc +1 more source
Optogenética y posibles terapias para la retinosis pigmentaria [PDF]
La retinosis pigmentaria (RP) es un grupo clínico y genéticamente heterogéneo de trastornos de la retina hereditarios caracterizados por una disfunción progresiva difusa de fotorreceptores predominantemente bastón, con la posterior degeneración de ...
Sansa Fayos, Marc
core
New methodologies for old problems: tridimensional gastrointestinal organoids and guts-on-a-chip
Objectives: The present review intended to present a critical overview of the methodological and experimental advances concerning tridimensional cell culture models within the scope of gastrointestinal research. Methods: A literature review was performed
Marna Eliana Sakalem +1 more
doaj +1 more source
Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. V: Manufacture and quality control. [PDF]
De Santis GC +9 more
europepmc +1 more source
Terapia del carcinoma de células renales [PDF]
El cáncer renal se encuentra entre los 10 tipos de cánceres más diagnosticados a nivel mundial, representando entre el 3-5% de todos los casos diagnosticados. Una detección precoz suele estar asociada con un pronóstico favorable.
Ramírez Sánchez, Pablo
core
Guidelines on the diagnosis and management of multiple myeloma treatment: Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular Project guidelines: Associação Médica Brasileira - 2022. Part I. [PDF]
Maiolino A +11 more
europepmc +1 more source
A terapia gênica e os princípios éticos [PDF]
Gene therapy is a form of genetic manipulation which tries to correct or to diminish the effects caused by genetic diseases. There are great hopes for the development of this type of therapy, specially for somatic genetic diseases that has no cure, but ...
Rodríguez Yunta, Eduardo
core +1 more source
Associação Brasileira de Hematologia, Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. Review article: Cell therapy in solid tumors. [PDF]
Nardo M, Motta TC, Colli LM, Avanzi MP.
europepmc +1 more source

