Results 71 to 80 of about 4,253 (175)

Terapia Celular: células CAR-T

, 2021
Therapy with CAR-T cells consists of the genetic modification of autologous T cells to express on their surface a chimeric antigenic receptor that will be directed to a target antigen, resulting in the elimination of the tumor due to the cytotoxic activity of the T cells. Currently, there are more than 500 clinical trials underway in the world in which
openaire   +1 more source

Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. IV: CAR-T cell therapy for multiple myeloma patients. [PDF]

Hematol Transfus Cell Ther, 2021
Maiolino A, Costa LJ, Pasquini M, Crusoe EQ, Vigorito AC, Salvino MA, Seguro FS, Filho JS, Hungria VTM.   +8 more
europepmc   +1 more source

Liver Fibrosis and Protection Mechanisms Action of Medicinal Plants Targeting Apoptosis of Hepatocytes and Hepatic Stellate Cells

Advances in Pharmacological Sciences, 2014
Following chronic liver injury, hepatocytes undergo apoptosis leading to activation of hepatic stellate cells (HSC). Consequently, activated HSC proliferate and produce excessive extracellular matrix, responsible for the scar formation.
Florent Duval, Jorge E. Moreno-Cuevas, Maria Teresa González-Garza, Carlos Rodríguez-Montalvo, Delia Elva Cruz-Vega   +4 more
doaj   +1 more source

Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. Special article: compassionate use and clinical trial on CAR-T cells. [PDF]

Hematol Transfus Cell Ther, 2021
De Santis GC.
europepmc   +1 more source

Terapia celular na Esclerose Lateral Amiotrófica

Revista Neurociências, 2001
Introdução. A Esclerose Lateral Amiotrófica é a doença de neurônio motor mais comum na idade adulta, com prognóstico sombrio e limitadas opções de tratamento o que leva a exploração de terapias alternativas. Método. Este trabalho, através de uma revisão da literatura, buscou descrever os avanços da utilização de células-tronco no tratamento da ...
Ronald Pallotta, Antônio Andrade, Clara Magalhaes Paiva   +2 more
openaire   +1 more source

Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular guidelines project: Associação Médica Brasileira - 2022. [PDF]

Hematol Transfus Cell Ther, 2022
Loggetto SR, Veríssimo MPA, Darrigo-Junior LG, Simões R, Bernardo WM, Braga JAP.   +5 more
europepmc   +1 more source

Transplantation of Stem Cells Obtained from Murine Dental Pulp Improves Pancreatic Damage, Renal Function, and Painful Diabetic Neuropathy in Diabetic Type 1 Mouse Model

Cell Transplantation, 2013
Diabetes mellitus (DM) is one of the most common and serious chronic diseases in the world. Here, we investigated the effects of mouse dental pulp stem cell (mDPSC) transplantation in a streptozotocin (STZ)-induced diabetes type 1 model.
Elisalva Teixeira Guimarães, Gabriela Da Silva Cruz, Tiago Farias De Almeida, Bruno Solano De Freitas Souza, Carla Martins Kaneto, Juliana Fraga Vasconcelos, Washington Luis Conrado Dos Santos, Ricardo Ribeiro-Dos-Santos, Cristiane Flora Villarreal, Milena Botelho Pereira Soares   +9 more
doaj   +1 more source

Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. VII. Present and future of technologies for production of CAR cell therapies. [PDF]

Hematol Transfus Cell Ther, 2021
Ramos RN, Picanço-Castro V, Oliveira TGM, Mendrone A, De Santis GC, Bonamino MH, Rocha V.   +6 more
europepmc   +1 more source

False-positive test results: prevalence, time trends, and factors associated with false-positive serological markers in blood donation screening

Hematology, Transfusion and Cell Therapy
Background and Objectives: False-positive serological results in blood donation screening may arise from antibody cross-reactivity, limitations in assay specificity, or low-level reactivity during early-stage infections, ultimately leading to donor ...
Lucas Kallas-Silva, Leandro Dinalli dos Santos, Valeria de Freitas Dutra, Jose Mauro Kutner, Carolina Bonet-Bub   +4 more
doaj   +1 more source

Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. VIII: CAR-T cells: preclinical development - Safety and efficacy evaluation. [PDF]

Hematol Transfus Cell Ther, 2021
Picanço-Castro V, Bonamino MH, Ramos RN, Guerino-Cunha RL, Oliveira TGM, Rego EM.   +5 more
europepmc   +1 more source