Results 71 to 80 of about 121,422 (225)

Adaptive Elastin‐Like Hydrogel with Unidirectional and Controllable Anisotropic Actuation for Soft Robotics and Tissue Engineering

Advanced Materials Technologies, Volume 10, Issue 17, September 4, 2025.
Fiber‐reinforced elastin‐like tubular scaffolds are engineered to achieve anisotropic and reversible actuation under external stimuli. By adjusting fiber's angle, actuation behavior is finely tuned, enabling distinct actuation responses, even within different regions of the same scaffold.
Federica Sallustio, Amanda Schmidt, Ikram El Maachi, Alexander Greenhalgh, Martin Frydrych, Stefan Jockenhoevel, José Carlos Rodríguez‐Cabello, Alicia Fernández‐Colino   +7 more
wiley   +1 more source

Enhancing adult hippocampal neurogenesis with lysophosphatidic acid: a proposal for erasing cocaine contextual memory [PDF]

, 2018
Stimulating adult hippocampal neurogenesis (AHN) has been uncovered as a promising approach in the manipulation of retrograde memories. This work aims to study whether increasing AHN with lysophosphatidic acid (LPA, an endogenous lysophospholipid with ...
Castilla Ortega, María Estela, Estivill-Torrús, Guillermo, Gil Rodríguez, Sara, Ladrón de Guevara-Miranda, David, Moreno-Fernández, Román D., Pavón, Francisco Javier, Rodríguez de Fonseca, Fernando, Rosell-del-Valle, Cristina, Santin-Nuñez, Luis Javier, Serrano, Antonia   +9 more
core  

The role of the endogenous opioid system in modulating orthodontic‐induced neurogenic inflammation of the dental pulp: A comprehensive review of the literature

International Endodontic Journal, Volume 58, Issue 8, Page 1126-1145, August 2025.
Abstract Background Orthodontic forces may lead to neurogenic inflammation in the dental pulp by triggering the release of somatosensory neuropeptides such as Substance P (SP), Calcitonin gene‐related peptide (CGRP) and Neurokinin A (NKA). In the vast majority of patients, acute symptoms are not triggered, probably due to the control of the neurogenic ...
Javier Caviedes‐Bucheli, Nestor Rios‐Osorio, Esteban Ulate‐Rodríguez, Hernan Dario Muñoz‐Alvear, José F. Gaviño‐Orduña, P. Sebastian Ortolani‐Seltenerich, Jose F. Gomez‐Sosa, Hugo Roberto Munoz   +7 more
wiley   +1 more source

Isolation, expansion, and characterization of equine adipose-derived stem cells [PDF]

, 2012
Devido aos excelentes resultados obtidos em pesquisas com células-tronco e suas aplicabilidades promissoras, a terapia com estas células encontra-se em momento de máxima ascensão, estimulando assim, inúmeras pesquisas.
Bravo, Martha de Oliveira, Dumont, Cinthia Beatriz da Silva, Filgueiras, Richard Rocha, Godoy, Roberta Ferro de, Hashimoto, Hetielle Harumi, Moraes, Júlia Miranda de   +5 more
core  

Biohybrid Vascular Graft Made of Textile‐Reinforced Elastin‐Like Recombinamers and Its Preservation via Drying Processes

Advanced Healthcare Materials, Volume 14, Issue 15, 10 June, 2025.
Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Dominic Pascal Andre, Stephan Ruetten, José Carlos Rodríguez‐Cabello, Stefan Jockenhoevel, Thomas Schmitz‐Rode, Alicia Fernández‐Colino   +5 more
wiley   +1 more source

El papel de los factores transcripcionales en el cáncer [PDF]

, 2015
[Resumen] Las terapias génicas actuales muestran resultados prometedores en el tratamiento de diversas enfermedades, entre ellas, el cáncer. Después de los avances logrados en los últimos años en el estudio de la maquinaria transcripcional, son muchas ...
Vázquez Arias, Alba
core  

T cell receptor signaling pathway is overexpressed in CD4+ T cells from HAM/TSP individuals

Brazilian Journal of Infectious Diseases, 2015
Human T-lymphotropic virus type 1 (HTLV-1) is a human retrovirus related to the chronic neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). CD4+ T cells activation appears to play a key role on HTLV-1 infection.
Mariana Tomazini Pinto, Tathiane Maistro Malta, Evandra Strazza Rodrigues, Osvaldo Massaiti Takayanagui, Yuetsu Tanaka, Dimas Tadeu Covas, Simone Kashima   +6 more
doaj   +1 more source

Vetores não virais com aplicação na terapia génica: os poliplexos [PDF]

, 2016
Monografia realizada no âmbito da unidade de Estágio Curricular do Mestrado Integrado em Ciências Farmacêuticas, apresentada à Faculdade de Farmácia da Universidade de CoimbraA terapia génica representa uma grande promessa no tratamento de doenças inatas
Loureiro, Ana Patrícia Cardoso
core  

Therapeutic effects of sphingosine kinase inhibitor N,N-dimethylsphingosine (DMS) in experimental chronic Chagas disease cardiomyopathy

Scientific Reports, 2017
Chagas disease cardiomyopathy is a parasite-driven inflammatory disease to which there are no effective treatments. Here we evaluated the therapeutic potential of N,N-dimethylsphingosine(DMS), which blocks the production of sphingosine-1-phosphate(S1P ...
Juliana Fraga Vasconcelos, Cássio Santana Meira, Daniela Nascimento Silva, Carolina Kymie Vasques Nonaka, Pâmela Santana Daltro, Simone Garcia Macambira, Pablo Daniel Domizi, Valéria Matos Borges, Ricardo Ribeiro-dos-Santos, Bruno Solano de Freitas Souza, Milena Botelho Pereira Soares   +10 more
doaj   +1 more source

Perspectivas de terapia celular em neurologia

Revista de Medicina, 2015
<p>Neste artigo de revisão, buscamos ressaltar alguns dos avanços mais recentes na pesquisa sobre células-tronco em neurologia. Além disso, buscamos demonstrar a direta associação entre seu funcionamento e mecanismos de replicação, diferenciação e maturação, além da terapêutica celular de algumas doenças neurológicas.
Fernando Onuchic, Chary Marquez Batista, Guilherme Lepski   +2 more
openaire   +2 more sources