Results 51 to 60 of about 4,796 (231)
Spontaneous Self‐Organized Order Emerging From Intrinsically Disordered Protein Polymers
WIREs Nanomedicine and Nanobiotechnology, Volume 17, Issue 1, January/February 2025.Harnessing the liquid‐liquid phase separation (LLPS) properties of intrinsically disordered protein polymers (IDPPs) enables the design and engineering of hierarchically self‐assembled protein materials with customizable structures and increasing complexity.
Sergio Acosta +4 more
wiley +1 more source
T cell receptor signaling pathway is overexpressed in CD4+ T cells from HAM/TSP individuals
Brazilian Journal of Infectious Diseases, 2015 Human T-lymphotropic virus type 1 (HTLV-1) is a human retrovirus related to the chronic neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). CD4+ T cells activation appears to play a key role on HTLV-1 infection.
Mariana Tomazini Pinto +6 more
doaj +1 more source
Inflammatory pathways and anti‐inflammatory therapies in sickle cell disease
HemaSphere, Volume 8, Issue 12, December 2024.Abstract Sickle cell disease (SCD) is a monogenic disease, resulting from a single‐point mutation, that presents a complex pathophysiology and high clinical heterogeneity. Inflammation stands as a prominent characteristic of SCD. Over the past few decades, the role of different cells and molecules in the regulation of the inflammatory process has been ...
Karina Tozatto‐Maio +3 more
wiley +1 more source
Scientific Reports, 2017 Chagas disease cardiomyopathy is a parasite-driven inflammatory disease to which there are no effective treatments. Here we evaluated the therapeutic potential of N,N-dimethylsphingosine(DMS), which blocks the production of sphingosine-1-phosphate(S1P ...
Juliana Fraga Vasconcelos +10 more
doaj +1 more source
Terapia celular cardíaca com células mesenquimatosas
Revista Portuguesa de Cardiologia, 2013 Resumo: A doença cardiovascular é uma das principais causas de mortalidade e morbilidade em todo o mundo e, apesar de os avanços na terapêutica médica e intervenção percutânea, o prognóstico de doenças como a cardiopatia isquémica e o pós-enfarte do miocárdio continuam a ser consideravelmente inferiores ao desejado.
João Pedro Lopes +4 more
openaire +2 more sources
British Journal of Haematology, Volume 205, Issue 4, Page 1346-1355, October 2024.Quantitative immunoprecipitation mass spectrometry (QIP‐MS) can accurately measure serum M‐protein with high sensitivity, and identify interferences caused by therapeutic monoclonal antibodies. We investigate the outcome of QIP‐MS in patients with multiple myeloma treated with the academic BCMA‐directed CAR T‐cell ARI0002h (Cesnicabtagene Autoleucel ...
Iñaki Ortiz de Landazuri +33 more
wiley +1 more source
Revista Colombiana de Cardiología, 2011 Este estudio tiene como objetivo evaluar la eficacia y seguridad de la terapia combinada de cardiomioplastia celular con el factor estimulante de colonias de granulocitos en pacientes con cardiopatía isquémica, y explorar posibles diferencias entre la ...
Juan M. Senior, MD., FACP +4 more
doaj +1 more source
Efeito da terapia celular com células-tronco mesenquimais da medula óssea e do tecido adiposo na regeneração do tecido ósseo [PDF]
, 2020 Gabriela Guaraldo Campos Tótoli
openalex +1 more source
CD8+ T Cell-Mediated Immunity during Trypanosoma cruzi Infection: A Path for Vaccine Development?
Mediators of Inflammation, 2014 MHC-restricted CD8+ T cells are important during infection with the intracellular protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease.
Fernando dos Santos Virgilio +5 more
doaj +1 more source
Neurobiology of Disease, 2012 Approximately 30% of patients with mesial temporal lobe epilepsy do not respond to treatment with antiepileptic drugs. We have previously shown that transplantation of mononuclear bone marrow cells (BMC) has an anticonvulsant effect in acute epilepsy ...
Zaquer S.M. Costa-Ferro +8 more
doaj +1 more source