Results 61 to 70 of about 121,019 (277)

Autologous adipose-derived mesenchymal stem cell therapy reverses detrusor underactivity: open clinical trial

open access: yesStem Cell Research & Therapy, 2023
Background Detrusor underactivity is a disease that can cause chronic urinary tract infection, urinary tract infection, urinary retention and kidney failure and has no effective treatment in traditional medicine.
Henrique Rodrigues Scherer Coelho   +4 more
doaj   +1 more source

Bases da terapia celular em cardiologia [PDF]

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2009
O implante de celulas para o tratamento de doencas cardiovasculares encontra-se sob investigacao em varios centros no mundo. Varias linhagens celulares, de celulas-tronco bem caracterizadas a fracoes contendo diferentes tipos de celulas, tem sido investigadas em modelos animais.
Carvalho, Antonio Carlos C.   +3 more
openaire   +3 more sources

Enhancing adult hippocampal neurogenesis with lysophosphatidic acid: a proposal for erasing cocaine contextual memory [PDF]

open access: yes, 2018
Stimulating adult hippocampal neurogenesis (AHN) has been uncovered as a promising approach in the manipulation of retrograde memories. This work aims to study whether increasing AHN with lysophosphatidic acid (LPA, an endogenous lysophospholipid with ...
Castilla Ortega, María Estela   +9 more
core  

Inflammatory pathways and anti‐inflammatory therapies in sickle cell disease

open access: yesHemaSphere, Volume 8, Issue 12, December 2024.
Abstract Sickle cell disease (SCD) is a monogenic disease, resulting from a single‐point mutation, that presents a complex pathophysiology and high clinical heterogeneity. Inflammation stands as a prominent characteristic of SCD. Over the past few decades, the role of different cells and molecules in the regulation of the inflammatory process has been ...
Karina Tozatto‐Maio   +3 more
wiley   +1 more source

Trasplante celular y terapia regenerativa con células madre [PDF]

open access: yes, 2008
Uno de los campos de la medicina que más expectativas ha levantado en los últimos años es la terapia celular con células madre. El aislamiento de células embrionarias humanas, la aparente e inesperada potencialidad de las células madre adultas y el ...
Prosper, F. (Felipe)
core  

The role of endothelial cells in hematologic malignancies [PDF]

open access: yes, 2008
A neoformação vascular constitui evento essencial para que ocorra o desenvolvimento humano. Nesta fase, o sistema vascular sofre expansão. Células endoteliais maduras (ECs) irão compor a parede dos vasos, enquanto células endoteliais oriundas da medula ...
CHAMONE, Dalton A. F.   +3 more
core   +2 more sources

Serum mass spectrometry for treatment monitoring in patients with multiple myeloma receiving ARI0002h CAR T‐cells

open access: yesBritish Journal of Haematology, Volume 205, Issue 4, Page 1346-1355, October 2024.
Quantitative immunoprecipitation mass spectrometry (QIP‐MS) can accurately measure serum M‐protein with high sensitivity, and identify interferences caused by therapeutic monoclonal antibodies. We investigate the outcome of QIP‐MS in patients with multiple myeloma treated with the academic BCMA‐directed CAR T‐cell ARI0002h (Cesnicabtagene Autoleucel ...
Iñaki Ortiz de Landazuri   +33 more
wiley   +1 more source

Influence of the level of neurological deficit on the efficacy of cell therapy in a model of severe traumatic brain injury [PDF]

open access: yes, 2012
Objetivo: Determinar si el nivel de déficit neurológico influye en la eficacia de la terapia celular con células madre mesenquimales (CMM) de la médula ósea en un modelo experimental crónico de lesión cerebral traumática. Material y métodos: Se sometió
Aguayo, C.   +5 more
core   +1 more source

T cell receptor signaling pathway is overexpressed in CD4+ T cells from HAM/TSP individuals

open access: yesBrazilian Journal of Infectious Diseases, 2015
Human T-lymphotropic virus type 1 (HTLV-1) is a human retrovirus related to the chronic neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). CD4+ T cells activation appears to play a key role on HTLV-1 infection.
Mariana Tomazini Pinto   +6 more
doaj   +1 more source

Therapeutic effects of sphingosine kinase inhibitor N,N-dimethylsphingosine (DMS) in experimental chronic Chagas disease cardiomyopathy

open access: yesScientific Reports, 2017
Chagas disease cardiomyopathy is a parasite-driven inflammatory disease to which there are no effective treatments. Here we evaluated the therapeutic potential of N,N-dimethylsphingosine(DMS), which blocks the production of sphingosine-1-phosphate(S1P ...
Juliana Fraga Vasconcelos   +10 more
doaj   +1 more source

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