Results 21 to 30 of about 14,058 (179)
We describe, for the first time, a new splice variant of the human TGF-β type II receptor (TβRII). The new transcript lacks 149 nucleotides, resulting in a frameshift and the emergence of an early stop codon, rendering a truncated mature protein of 57 ...
Marcela Soledad Bertolio +11 more
doaj +1 more source
Neuropilin-1: A Conserved Entry Receptor for SARS-CoV-2 and a Potential Therapeutic Target
Background/Objectives: Neuropilin-1 (NRP1) is a key co-receptor for SARS-CoV-2, complementing the ACE2 receptor. Several investigations have documented highly conserved sequences in this receptor, supporting the implication of NRP1 as a key mediator in ...
Vivany Maydel Sierra-Sánchez +9 more
doaj +1 more source
Princípios de terapia génica [PDF]
Podríamos definir la terapia génica como la introducción de un gen foráneo en el ser humano con fines terapéuticos. La terapia génica comenzó a ser utilizada en el ser humano a principios de los años 90 y en los últimos años ha empezado a dar sus frutos.
Reverter Velasco, Naiara
core
A Photonastic Prototissue Capable of Photo‐Mechano‐Chemical Transduction
Mimicking energy transduction in prototissue assemblies remains a challenge of bottom‐up synthetic biology. In this work, prototissues integrating protocells with photothermal gold nanoparticle proto‐organelles and a thermoresponsive polymeric proto‐cortex are developed.
Agostino Galanti +7 more
wiley +1 more source
Background: Cytokine induced killer cells (CIK) are an advanced therapeutic medicinal product (ATMP) composed of activated, mostly CD8+, T cells with anti‐tumor but little graft versus host disease (GvHD) activity, even in an allogeneic setting.
J. Golay +5 more
wiley +1 more source
Protective Effects of Moringa oleifera on HBV Genotypes C and H Transiently Transfected Huh7 Cells
Chronic hepatitis B infection treatment implicates a long-lasting treatment. M. oleifera extracts contain compounds with antiviral, antioxidant, and antifibrotic properties. In this study, the effect of M.
Sina Feustel +6 more
doaj +1 more source
Coacervate Vesicles as Adaptive Platforms for Synthetic Biology and Smart Materials
Coacervate vesicles are emerging protocells that merge coacervates’ functionality within membranised architectures. Their diverse formation mechanisms from coacervate droplets yield tunable, responsive systems with broad potential, from synthetic biology to smart materials, offering a powerful, programmable platform for next‐generation bioinspired ...
Francesco Vicentini +2 more
wiley +1 more source
Background: Immunotherapy using patient‐derived T cells engineered to express a chimeric antigen receptor (CAR) by viral vectors has achieved complete remission and durable response in highly refractory populations. Unmodified allogeneic Cytokine Induced Killer (CIK) cells (CD3+CD56+ T cells) have clearly demonstrated a high profile of safety in ALL ...
C.F. Magnani +22 more
wiley +1 more source
Nuevos politriazoles protonables para terapia génica [PDF]
La terapia génica consiste en utilizar genes para tratar o prevenir enfermedades. En la actualidad es quizás junto a la inmunonoterapia una de las estrategias más prometedoras en lo que se refiere al tratamiento del cáncer.
Ramírez Espinosa, María
core
Cerium oxide nanoparticles: a promising nanotherapy approach for chronic degenerative diseases
Oxidative stress is a process caused by excess-free radicals and reactive oxygen species (ROS), which contribute to the onset and progression of various chronic degenerative diseases.
Hugo Christian Monroy-Ramirez +7 more
doaj +1 more source

