Results 21 to 30 of about 14,020 (183)

Princípios de terapia génica [PDF]

open access: yes, 2016
Podríamos definir la terapia génica como la introducción de un gen foráneo en el ser humano con fines terapéuticos. La terapia génica comenzó a ser utilizada en el ser humano a principios de los años 90 y en los últimos años ha empezado a dar sus frutos.
Reverter Velasco, Naiara
core  

A Photonastic Prototissue Capable of Photo‐Mechano‐Chemical Transduction

open access: yesAdvanced Materials, Volume 37, Issue 40, October 9, 2025.
Mimicking energy transduction in prototissue assemblies remains a challenge of bottom‐up synthetic biology. In this work, prototissues integrating protocells with photothermal gold nanoparticle proto‐organelles and a thermoresponsive polymeric proto‐cortex are developed.
Agostino Galanti   +7 more
wiley   +1 more source

PF435 A FLEXIBLE THERAPEUTIC STRATEGY FOR LEUKEMIA USING EX‐VIVO EXPANDED T CELLS COMBINED WITH BISPECIFIC ANTIBODIES

open access: yesHemaSphere, Volume 3, Issue S1, Page 170-171, June 2019., 2019
Background: Cytokine induced killer cells (CIK) are an advanced therapeutic medicinal product (ATMP) composed of activated, mostly CD8+, T cells with anti‐tumor but little graft versus host disease (GvHD) activity, even in an allogeneic setting.
J. Golay   +5 more
wiley   +1 more source

Protective Effects of Moringa oleifera on HBV Genotypes C and H Transiently Transfected Huh7 Cells

open access: yesJournal of Immunology Research, 2017
Chronic hepatitis B infection treatment implicates a long-lasting treatment. M. oleifera extracts contain compounds with antiviral, antioxidant, and antifibrotic properties. In this study, the effect of M.
Sina Feustel   +6 more
doaj   +1 more source

Coacervate Vesicles as Adaptive Platforms for Synthetic Biology and Smart Materials

open access: yesChemistry – A European Journal, Volume 31, Issue 54, September 24, 2025.
Coacervate vesicles are emerging protocells that merge coacervates’ functionality within membranised architectures. Their diverse formation mechanisms from coacervate droplets yield tunable, responsive systems with broad potential, from synthetic biology to smart materials, offering a powerful, programmable platform for next‐generation bioinspired ...
Francesco Vicentini   +2 more
wiley   +1 more source

PF436 GMP MANUFACTURING OF ALLOGENEIC CD19 CHIMERIC ANTIGEN RECEPTOR (CAR) CYTOKINE INDUCED KILLER (CIK) CELLS WITH SLEEPING BEAUTY (SB) TRANSPOSON FOR ADOPTIVE IMMUNOTHERAPY

open access: yesHemaSphere, Volume 3, Issue S1, Page 171, June 2019., 2019
Background: Immunotherapy using patient‐derived T cells engineered to express a chimeric antigen receptor (CAR) by viral vectors has achieved complete remission and durable response in highly refractory populations. Unmodified allogeneic Cytokine Induced Killer (CIK) cells (CD3+CD56+ T cells) have clearly demonstrated a high profile of safety in ALL ...
C.F. Magnani   +22 more
wiley   +1 more source

Cerium oxide nanoparticles: a promising nanotherapy approach for chronic degenerative diseases

open access: yesJournal of Materials Science: Materials in Engineering
Oxidative stress is a process caused by excess-free radicals and reactive oxygen species (ROS), which contribute to the onset and progression of various chronic degenerative diseases.
Hugo Christian Monroy-Ramirez   +7 more
doaj   +1 more source

Attenuation of Pulmonary Damage Associated with COPD in a Cadmium-Exposed Model Due to the Administration of a siRNA Targeting PAD4

open access: yesScientia Pharmaceutica
Chronic obstructive pulmonary disease (COPD), characterised by persistent airflow limitation during breathing, is considered to be the third leading cause of death worldwide.
Sergio Adrian Ocampo-Ortega   +9 more
doaj   +1 more source

Optogenética y posibles terapias para la retinosis pigmentaria [PDF]

open access: yes, 2019
La retinosis pigmentaria (RP) es un grupo clínico y genéticamente heterogéneo de trastornos de la retina hereditarios caracterizados por una disfunción progresiva difusa de fotorreceptores predominantemente bastón, con la posterior degeneración de ...
Sansa Fayos, Marc
core  

PF437 PLATINUM TALEN‐MEDIATED NON‐VIRAL T CELL RECEPTOR GENE KNOCK‐IN FACILITATES UNIVERSAL T CELL GENOME EDITING FOR MANUFACTURING OF THERAPEUTIC IMMUNE CELLS

open access: yesHemaSphere, Volume 3, Issue S1, Page 171-172, June 2019., 2019
Background: Adoptive transfer of T cells genetically modified to express T‐cell receptors (TCRs) directed against tumor‐specific antigens is an emerging therapeutic tool for refractory hematologic and non‐hematologic neoplasms. Although accumulating experiences in their clinical use have shown great promise, challenges still remain because mispairing ...
Y. Honjo   +7 more
wiley   +1 more source

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