Results 11 to 20 of about 8,189 (211)

Evaluation of the Pro-, Anti-Inflammatory, and Anabolic Effects of Autologous Platelet-Rich Gel Supernatants in an in vitro Coculture System of Canine Osteoarthritis

Veterinary Medicine International, 2022
There are scarce in vitro studies indicating the basic mechanisms of why platelet-rich plasma (PRP) is useful in the clinical management of dogs with naturally occurring OA. Methods.
Miller Gallego, Catalina López, Jorge U. Carmona   +2 more
doaj   +2 more sources

Temporal Release and Denature of Several Mediators in Pure Platelet-Rich Plasma and Temperature-Induced Platelet Lysates Derived from a Similar Bovine Platelet Concentrate

Veterinary Medicine International, 2022
There is scarce information about bovine platelet-rich plasma/platelet-rich gel (PRP/PRG) and related hemocomponents (HCs), such as platelet lysates (PLs), including growth factor (GF) and cytokine concentrations, and how the stability of these ...
Jorge U. Carmona, Catalina López, Alejandro Ceballos-Márquez   +2 more
doaj   +2 more sources

Study of a Two-Step Centrifugation Protocol for Concentrating Cells and Growth Factors in Bovine Platelet-Rich Plasma

Veterinary Medicine International, 2017
There is a lack of information about the methods used for bovine platelet-rich plasma (PRP)/platelet-rich gel (PRG) procurement, including information on platelet (PLT), white blood cell (WBC) in PRP, and growth factor release from PRG supernatants.
Claudia M. Gutiérrez, Catalina López, Carlos E. Giraldo, Jorge U. Carmona   +3 more
doaj   +2 more sources

Proinflammatory and Anabolic Gene Expression Effects of Platelet-Rich Gel Supernatants on Equine Synovial Membrane Explants Challenged with Lipopolysaccharide

Veterinary Medicine International, 2017
Platelet-rich plasma (PRP) preparations are used in horses with osteoarthritis (OA). However, some controversies remain regarding the ideal concentration of platelets and leukocytes to produce an adequate anti-inflammatory and anabolic response in the ...
Jorge U. Carmona, Diana L. Ríos, Catalina López, María E. Álvarez, Jorge E. Pérez   +4 more
doaj   +2 more sources

Immortalizing Mesenchymal Stromal Cells from Aged Donors While Keeping Their Essential Features

Stem Cells International, 2020
Human bone marrow-derived mesenchymal stromal cells (MSCs) obtained from aged patients are prone to senesce and diminish their differentiation potential, therefore limiting their usefulness for osteochondral regenerative medicine approaches or to study ...
María Piñeiro-Ramil, Rocío Castro-Viñuelas, Clara Sanjurjo-Rodríguez, Silvia Rodríguez-Fernández, Tamara Hermida-Gómez, Francisco J. Blanco-García, Isaac Fuentes-Boquete, Silvia Díaz-Prado   +7 more
doaj   +2 more sources

Hacia la terapia celular y la medicina regenerativa: Reprogramación celular

Revista de la Facultad de Ciencias Médicas de Córdoba, 2012
Los Doctores Sir John B. Gurdon, nacido en Reino Unido en 1933, del Instituto Gurdon (Cambridge, Reino Unido), y Shin´ya Yamanaka, nacido en Japón en 1962, de la Universidad de Kyoto (Japón), recibieron el Premio Nobel de Medicina 2012 por sus ...
Aldo R. Eynard, Elio A. Soria
doaj   +2 more sources

Distinct roles of amniotic membrane epithelial (hAEC) and mesenchymal stromal cells (hAMSC) in amniotic membrane-driven wound healing [PDF]

Scientific Reports
Human skin wound healing is a complex process involving sequential cellular events to restore skin integrity. Chronic wounds fail to heal due to impaired keratinocyte activation and dysregulated cytokine signaling.
M. Alcaraz, I. Hernández-Mármol, J. M. Puente-Cuadrado, M. Rodríguez-Valiente, A. R. Silini, O. Parolini, F. J. Nicolás   +6 more
doaj   +2 more sources

Biohybrid Vascular Graft Made of Textile-Reinforced Elastin-Like Recombinamers and Its Preservation via Drying Processes. [PDF]

Adv Healthc Mater
Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Andre DP, Ruetten S, Rodríguez-Cabello JC, Jockenhoevel S, Schmitz-Rode T, Fernández-Colino A.   +5 more
europepmc   +2 more sources

¿Es realmente útil el tratamiento con la terapia celular regenerativa?

Revista Cubana de Hematología, Inmunología y Hemoterapia
La Medicina Regenerativa se apoya fundamentalmente en la terapia celular, en la administración de factores bioactivos, en la ingeniería de tejidos y en la terapia génica.
Porfirio Hernández Ramírez
doaj   +1 more source

Oligodendrocyte origin and development in the zebrafish visual system

Journal of Comparative Neurology, Volume 531, Issue 4, Page 515-527, March 2023., 2023
Graphical Abstract The first oligodendrocyte progenitor cells (OPCs, olig2:EGFP/Sox2, yellow cells) are detected in the preoptical area of the hypothalamus at 2 dpf. One day later, 3 dpf, these cells invade the optic chiasm and colonize the postchiasmatic region first and the prechiasmatic later (yellow cells). As they differentiate to oligodendrocytes,
Adrián Santos‐Ledo, Cristina Pérez‐Montes, Laura DeOliveira‐Mello, Rosario Arévalo, Almudena Velasco   +4 more
wiley   +1 more source