Results 11 to 20 of about 1,927 (151)

The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells.

PLoS ONE, 2019
Human endogenous retroviruses are remnants of ancient germline infections that make up approximately 8% of the modern human genome. The HERV-K (HML-2) family is one of the most recent entrants into the human germline, these viruses appear to be ...
Susana M Chan, Tamar Sapir, Sung-Soo Park, Jean-François Rual, Rafael Contreras-Galindo, Orly Reiner, David M Markovitz   +6 more
doaj   +2 more sources

A Giant Primary Mediastinal Teratocarcinoma in a Male Adult

Case Reports in Surgery, 2019
Germ cell tumors (GCTs) arise along the midline, in which 50-70% of extragonadal GCTs occur in the mediastinum. Malignant GCTs are more common in males, while benign GCTs occur equally in both males and females.
Muneera Al-Khalifa, Sara Alsaad, Habib Al-Tareef, Zaid Arekat, Abdulla Darwish   +4 more
doaj   +2 more sources

Expression of Sec61a in F9 and P19 teratocarcinoma cells after retinoic acid treatment

Brazilian Journal of Biology, 2003
Nascent procollagen peptides and other secretory proteins are transported across the endoplasmic reticulum (RE) membrane through a protein-conducting channel called the translocon.
Ferreira L. R., Velano C. E. E., Braga E. C., Paula C. C., Martélli-Junior H., Sauk J. J.   +5 more
doaj   +1 more source

Dual functions of silver nanoparticles in F9 teratocarcinoma stem cells, a suitable model for evaluating cytotoxicity- and differentiation-mediated cancer therapy

International Journal of Nanomedicine, 2017
Jae Woong Han, Sangiliyandi Gurunathan, Yun-Jung Choi, Jin-Hoi Kim Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Center (SRC), Konkuk University, Seoul, Republic of Korea Background: Silver nanoparticles (AgNPs) exhibit
Han JW, Gurunathan S, Choi YJ, Kim JH
doaj   +1 more source

A rare case of giant teratocarcinoma of the testis with accumulation of fluid

Urology Case Reports, 2022
Testicular cancer is one of the most curable cancers. However, the course of the disease largely depends on the clinical stage at diagnosis, and there are still cases where the tumor size is large, which makes surgical treatment challenging.A 30-year-old
Karolina Majewska, Wiktoria Zawolik, Aleksander Targoński, Michał Tkocz   +3 more
doaj   +1 more source

Epigenetic modulation of differentiation in CE44 teratocarcinoma [PDF]

, 2011
Teratocarcinoma is a mixed germ cell tumor histologically composed of embryonal carcinoma cells and embryonic and extraembryonic tissues. In the present work we have used the CE44 teratocarcinoma, which is a tumor cell line derived from the OTT6050 ...
Aréchaga, J., Simón, J., Lacalle, J., García Sanz, M., Hilario, Enrique, Álvarez, A.   +5 more
core   +2 more sources

Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

Journal for ImmunoTherapy of Cancer, 2022
Background One of the main difficulties of adoptive cell therapies with chimeric antigen receptor (CAR)-T cells in solid tumors is the identification of specific target antigens.
Felipe Prosper, Sandra Hervás-Stubbs, Juan Jose Lasarte, Noelia Casares, Teresa Lozano, Diego Serrano, Carlos E De Andrea, Alfonso Calvo, Enrique Conde, Celia Martín-Otal, Aritz Lasarte-Cia, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, José Echeveste, Amaia Vilas, Juan Roberto Rodriguez-Madoz, Jesús San Miguel   +18 more
doaj   +1 more source

Gene Expression Profiling of Mouse Teratocarcinomas Uncovers Epigenetic Changes Associated with the Transformation of Mouse Embryonic Stem Cells

Neoplasia: An International Journal for Oncology Research, 2004
The molecular mechanisms of the development of teratocarcinomas from stem cells are largely unknown. To determine which genes are associated with the transformation of these cells, we have performed oligonucleotide microarray analysis, using Affymetrix ...
Allison E Bonner, Yian Wang, Ming You
doaj   +1 more source

The class I-specific HDAC inhibitor MS-275 modulates the differentiation potential of mouse embryonic stem cells

Biology Open, 2013
Summary Exploitation of embryonic stem cells (ESC) for therapeutic use and biomedical applications is severely hampered by the risk of teratocarcinoma formation.
Gianluigi Franci, Laura Casalino, Francesca Petraglia, Marco Miceli, Roberta Menafra, Branka Radic, Valeria Tarallo, Monica Vitale, Marzia Scarfò, Gabriella Pocsfalvi, Alfonso Baldi, Concetta Ambrosino, Nicola Zambrano, Eduardo Patriarca, Sandro De Falco, Gabriella Minchiotti, Hendrik G. Stunnenberg, Lucia Altucci   +17 more
doaj   +1 more source

Sec61alpha synthesis is enhanced during translocation of nascent chains of collagen type IV in F9 teratocarcinoma cells after retinoic acid treatment

Brazilian Journal of Medical and Biological Research, 2003
Nascent procollagen peptides and other secretory proteins are transported across the endoplasmic reticulum (ER) membrane through a protein-conducting channel called translocon.
L.R. Ferreira, C.E.E. Velano, E.C. Braga, C.C. Paula, H. Martéli Junior, J.J. Sauk   +5 more
doaj   +1 more source