Results 21 to 30 of about 10,766 (249)

Teratocarcinoma In A Non Seminomatous, Mixed Germ Cell Tumour of the Testis–A Rare Entity [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Mixed Germ Cell Tumours (MGCTs) of the testis are the second most common testicular tumours. In the 10 years retrospective study which was done on testicular neoplasms at our institute, this reported case accounted for 0.4%. We are presenting the case
Gayathri Malavalli   +2 more
doaj   +1 more source

Investigating the anticancer efficacy of biogenic synthesized MgONPs: An in vitro analysis

open access: yesFrontiers in Chemistry, 2022
The biogenic approach of synthesizing metal nanoparticles is an exciting and interesting research area with a wide range of applications. The present study reports a simple, convenient, low-cost method for synthesizing magnesium oxide nanoparticles ...
Shams Tabrez   +8 more
doaj   +1 more source

A rare case of giant teratocarcinoma of the testis with accumulation of fluid

open access: yesUrology Case Reports, 2022
Testicular cancer is one of the most curable cancers. However, the course of the disease largely depends on the clinical stage at diagnosis, and there are still cases where the tumor size is large, which makes surgical treatment challenging.A 30-year-old
Karolina Majewska   +3 more
doaj   +1 more source

Intracranial Teratocarcinoma in a Dog [PDF]

open access: yesVeterinary Pathology, 1980
Spontaneous teratomas are rare in domestic animals [3]. Most reported tumors are gonadal in origin and are seldom malignant [3, 16, 171. Extragonadal teratomas are extremely rare in animals; they have been reported in the cranium of the horse, ox, guinea pig, chicken and rabbit [I-3, 8, 10, 16, 221.
A K, Patnaik, L A, Nafe
openaire   +2 more sources

Expression dynamics of Mage family genes during self-renewal and differentiation of mouse pluripotent stem and teratocarcinoma cells

open access: yesOncoTarget, 2019
The biological roles of cancer-testis antigens of the Melanoma antigen (Mage) family in mammalian development, stem cell differentiation and carcinogenesis are largely unknown.
O. Gordeeva, A. Gordeev, S. Khaydukov
semanticscholar   +1 more source

A Novel Tight Junction-Nuclear Receptor Signaling Pathway Regulating Cancer Progression. [PDF]

open access: yesPathol Int
ABSTRACT Nuclear receptors (NRs) are lipid ligand‐binding transcription factors, with 48 members having been identified in humans to date. They are involved in diverse physiological processes, including development and homeostasis, and are also implicated in the pathogenesis of various diseases, most notably cancer.
Sugimoto K, Chiba H.
europepmc   +2 more sources

New Histone Demethylase LSD1 Inhibitor Selectively Targets Teratocarcinoma and Embryonic Carcinoma Cells

open access: yesBioorganic & Medicinal Chemistry, 2018
LSD1/KDM1 is a histone demethylase that preferentially removes methyl groups from the mono- and di-methylated lysine 4 in histone H3 (H3K4), key marks for active chromatin for transcriptional activation.
Nam Hoang   +10 more
semanticscholar   +1 more source

Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Background One of the main difficulties of adoptive cell therapies with chimeric antigen receptor (CAR)-T cells in solid tumors is the identification of specific target antigens.
Felipe Prosper   +18 more
doaj   +1 more source

Gene Expression Profiling of Mouse Teratocarcinomas Uncovers Epigenetic Changes Associated with the Transformation of Mouse Embryonic Stem Cells

open access: yesNeoplasia: An International Journal for Oncology Research, 2004
The molecular mechanisms of the development of teratocarcinomas from stem cells are largely unknown. To determine which genes are associated with the transformation of these cells, we have performed oligonucleotide microarray analysis, using Affymetrix ...
Allison E Bonner, Yian Wang, Ming You
doaj   +1 more source

The class I-specific HDAC inhibitor MS-275 modulates the differentiation potential of mouse embryonic stem cells

open access: yesBiology Open, 2013
Summary Exploitation of embryonic stem cells (ESC) for therapeutic use and biomedical applications is severely hampered by the risk of teratocarcinoma formation.
Gianluigi Franci   +17 more
doaj   +1 more source

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