Results 141 to 150 of about 13,919 (330)

Pregnancy outcomes following exposure to galcanezumab: Analysis of cases from the galcanezumab clinical trials and postmarketing database

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study was conducted to describe pregnancy outcomes reported following maternal or paternal exposure to galcanezumab in clinical trials and postmarketing surveillance. Background Galcanezumab is a calcitonin gene‐related peptide‐inhibiting monoclonal antibody indicated for the preventive treatment of migraine.
Irene Boz, Jan Lewis Brandes, Christopher Robinson, Maria Fernanda Scantamburlo Fernandes, Sarah Lipsius, LaRonda Morford, Enemona Emmanuel Adaji, Anaclara Prada Jardim, Holland C. Detke   +8 more
wiley   +1 more source

Edukasi Regulasi Emosi dan Faktor Teratogen pada Fase Prenatal kepada Ibu Hamil di Posbindu Bonsai 1 Desa Kalihurip

Kegiatan edukasi mengenai regulasi emosi dan faktor teratogen pada fase prenatal dilaksanakan di Posbindu Bonsai 1 Desa Kalihurip, Karawang, untuk meningkatkan kesadaran danpengetahuan ibu hamil tentang pentingnya menjaga keseimbangan emosional serta ...
Bayu Priyatna, Kokom Komariah
core   +1 more source

The Teratogenic Effects of Antiepileptic Drug, Topiramate, on the Development of Chick Embryos

Siriraj Medical Journal, 2017
Background: Anti-epileptic drugs are known to be the risk of teratogenicity. Topiramate (TPM) is a new kind of such drug, for which no research has confirmed the incidence of producing congenital abnormalities.
Jantima Roongruangchai
doaj  

Identification of differentially expressed genes in fetal rat forebrain exposed to a teratogen by cDNA microarray analysis [PDF]

, 2007
In an attempt to understand the molecular basis underlying the neural tube defects induced by the teratogen, cyclophosphamide (CP), cDNA microarray analysis was carried out in neural tubes of embryos derived from normal and CP-treated rats.
Hao, A.J., Gopalakrishnakone, P., Dheen, S.T., Ling, E. A., Fu, J.   +4 more
core  

Embryolethality of new herbicides is not detected by the micromass teratogen tests.

, 1991
New herbicidal compounds (11 pyrimidine-diones, 3 benzoates and 1 sulfonamide) were found to be embryolethal but not teratogenic in rats. The range of the embryolethal dose varied from 0.2 to greater than 200 mg/kg.
Tsuchiya M, Kistler A, Bürgin H, Tsuchiya T, Winternitz P   +4 more
core   +1 more source

Cosmetic Dermatology in Pregnancy and Lactation: A Risk–Benefit Framework for Clinical Practice

International Journal of Dermatology, EarlyView.
Summary of the safety profile of common cosmetic dermatology interventions during pregnancy and lactation. ABSTRACT Cosmetic dermatologic products and procedures are increasingly utilized by women of reproductive age, including those who are pregnant or lactating.
Timea Kovacs, Umer Nadir, Michael Goldenberg, Thomas E. Rohrer, Deirdre Hooper, George M. Jeha, Stanislav N. Tolkachjov   +6 more
wiley   +1 more source

Embryonic lipid metabolism and the actions of the teratogen valproic acid.

, 1988
Lipid metabolism and the actions of valproic acid, a human teratogen, have been studied in the organogenesis-stage rat conceptus, using whole embryo culture techniques. All major lipid classes, particularly phospholipids, cholesterol and triacylglycerols,
Clarke, David Oakley.
core  

Consensus recommendations for Trichophyton indotineae: A modified Delphi study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A modified Delphi consensus for suspected terbinafine‐resistant T. indotineae: confirm dermatophytes with KOH microscopy/culture and species‐level PCR/ITS sequencing. Itraconazole is recommended as first‐line systemic therapy, with luliconazole 1% cream as a topical adjunct. Posaconazole may be considered if itraconazole fails, while keeping antifungal
Aditya K. Gupta, Mesbah Talukder, Ditte Marie L. Saunte, Roderick James Hay, Michael Arabatzis, Avrom S. Caplan, Eran Galili, Eckart Haneke, Matilde Iorizzo, Riad Kassem, Ananta Khurana, Shari R. Lipner, Anna Lyakhovitsky, Brian W. Morrison, Vincent Piguet, Bianca Maria Piraccini, Carmen Rodríguez‐Cerdeira, Avner Shemer, Michela Starace, Olav Sundnes, Antonella Tosti   +20 more
wiley   +1 more source

Modulation of sebocyte function in acne: A pathway‐inclusive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis, Apostolos Pappas, Katja Martin, Mauro Picardo   +3 more
wiley   +1 more source

Comparative anatomy of chicken and human forelimb muscles: Implications for human congenital conditions through developmental models

Journal of Anatomy, EarlyView.
The chicken embryo is an accessible, low‐cost and genetically tractable model for studying limb development and congenital limb differences. We directly compared chicken and human limb musculature using published evidence alongside our own data and observations.
Julia Dong Hwa Oh, Megan G. Davey, Melina Eleni Bell, Meera Arun Singhal, Wee Leon Lam   +4 more
wiley   +1 more source