Results 181 to 190 of about 31,463 (288)

Oncogenic and teratogenic effects of <i>Trp53</i>^Y217C, an inflammation-prone mouse model of the human hotspot mutant <i>TP53</i>^Y220C. [PDF]

Elife
Jaber S, Eldawra E, Rakotopare J, Simeonova I, Lejour V, Gabriel M, Cañeque T, Volochtchouk V, Licaj M, Fajac A, Rodriguez R, Morillon A, Bardot B, Toledo F.   +13 more
europepmc   +1 more source

The Safety of Treating Women With Inflammatory Bowel Disease With Allopurinol and Low‐Dose Thiopurine During Pregnancy: A Single‐Center Experience

JCC Plus, Volume 1, Issue 4, July 2026.
ABSTRACT Background Low‐dose thiopurine therapy in combination with allopurinol (LD‐THIO/ALLO) is a widely used treatment for inflammatory bowel disease (IBD). However, little is known about the effects of in utero exposure to this combination on pregnancy and birth outcomes.
Kavitha Sivananthan, Signe Wildt, Marianne Kiszka‐Kanowitz, Gitte Pedersen, Ida Vind, Inge Nordgaard‐Lassen, Andreas Munk Petersen, Johan Burisch, Helle Kristensen, Klaus Theede   +9 more
wiley   +1 more source

Phytochemical evaluation, embryotoxic, and teratogenic effects of Buwakan (Decalobanthus peltatus (L.) A.R.Simões & Staples) leaf extracts on duck embryo. [PDF]

Environ Anal Health Toxicol
Subebe MJB, Ogaro JC, Dayon ML, Manting MME, Murashima A, Omori A, Guihawan JQ, Uy MM, Mazahery ARF, Villacorte-Tabelin M.   +9 more
europepmc   +1 more source

Embryotoxic and Teratogenic Effects of Tartrazine in Rats. [PDF]

Toxicol Res, 2019
Hashem MM, Abd-Elhakim YM, Abo-El-Sooud K, Eleiwa MME.   +3 more
europepmc   +1 more source

Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation

The Laryngoscope, Volume 136, Issue 7, Page 3240-3245, July 2026.
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal, Jackie Chiang, Evan J. Propst, Nikolaus E. Wolter   +3 more
wiley   +1 more source

Society for Maternal‐Fetal Medicine Statement: Acetaminophen use during pregnancy

Pregnancy, Volume 2, Issue 4, July 2026.
Abstract Acetaminophen has long been considered safe to use during pregnancy. A growing body of cohort studies and meta‐analyses has explored the potential association between prenatal acetaminophen use and neurodevelopmental outcomes in children. Although some studies report modestly increased risks of neurodevelopmental disorders in children exposed ...
Society for Maternal‐Fetal Medicine (SMFM), SMFM Publications Committee   +1 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Antioxidant role of melatonin against nicotine's teratogenic effects on embryonic bone development. [PDF]

Iran J Basic Med Sci, 2018
Yılmaz H, Ertekin T, Atay E, Nisari M, Susar Güler H, Al Ö, Payas A, Yılmaz S.   +7 more
europepmc   +1 more source

Prenatal Prescription Opioid Analgesic Exposure and Academic Performance in Third Grade Children: A Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 8, Page 1658-1670, July 2026.
ABSTRACT Objective To evaluate the association between prenatal exposure to opioids analgesics and academic performance in third grade children. Design Population‐based cohort study using linked data from New South Wales birth records, medicine dispensing data, and national standardised test results.
Bianca Varney, Helga Zoega, Malcolm B. Gillies, Claudia Bruno, Alys Havard, Antonia Shand, Natasha Nassar, Jonathan Brett   +7 more
wiley   +1 more source

Teratogenic Effects of Topiramate in a Zebrafish Model. [PDF]

Int J Mol Sci, 2017
Lai YH, Ding YJ, Moses D, Chen YH.
europepmc   +1 more source