Results 41 to 50 of about 26,590 (258)
British Journal of Clinical Pharmacology, EarlyView.Abstract Congenital ichthyoses (CI) are rare, inherited skin disorders characterized by hyperkeratosis, scaling and fissuring that significantly impair patients' quality of life. Treatment options are limited, with systemic retinoids reserved for severe cases owing to their adverse effect profile.
Holm Schneider +10 more
wiley +1 more source
Investigation on the teratogenic and embryotoxic effects of nanozeolite on chick embryos model [PDF]
Nanomedicine Research Journal, 2018 Objective(s): In veterinary medicine, zeolites are used as toxin binder in animal feed, ammonia purification of aquatic pools, animal smell and moisture control.
Marzie Hejazy +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Thalidomide, a sedative drug that was once excluded from the market owing to its teratogenic properties, was later found to be effective in treating multiple myeloma.
Tomomi Sato +4 more
doaj +1 more source
Learning with Patient Campaigners About a German Drug Scandal
Berichte zur Wissenschaftsgeschichte, EarlyView.The West German drug Duogynon was internationally marketed as a “hormone pregnancy test” (HPT) between the 1950s and 1980s. In the late 1960s it came under suspicion for inducing miscarriage, spina bifida, and a spectrum of birth defects similar to those caused by the sedative thalidomide.
Jesse Olszynko‐Gryn +3 more
wiley +1 more source
Benzene histotoxic and teratogenic Effects in exposed Mice
Kufa Journal for Veterinary Medical Sciences, 2017 Throughout the last two decades, benzene was a prominent source of an occupational and environmental pollution in Iraq. Especially from direct contact with private electric generators which were installed closer to homes or even inside every home in ...
Hussamadin kadhim +4 more
doaj +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.Abstract Industrial wastewater contamination by azo dyes poses a significant environmental challenge. This study reports the green synthesis of bimetallic iron/nickel (Fe/Ni) nanoparticles using moringa leaf extract, which acted as both a reducing and capping agent, and their incorporation into polyethersulphone (PES) membranes to produce eco‐friendly ...
Qusay A. Almajras +7 more
wiley +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2007 Background&Objective: Acetaminophen is a drug that is used commonly in the all time of pregnancy as a antipyretic and analgestic. The aim of this study was to determine teratogenic effects of this drug when it is used continuously before and during ...
Afshar M, Hamy J, Boghrati M
doaj
Fluconazole-Associated Birth Defects: A Comprehensive Review
INNOVATIONS in Pharmacy, 2014 Background: The August 2013 publication of a large historical cohort study in the New England Journal of Medicine has reignited interest in the potential teratogenic effects of fluconazole when used in pregnant females.
Janssen M. Firth +2 more
doaj +1 more source
A hypothesis to derive the shape of the dose–response curve for teratogenic radiation effects
Environmental Health, 2022 Reports of adverse pregnancy outcomes after in utero exposure to very low levels of ionizing radiation are inconsistent with a threshold dose of 100 mSv for teratogenic effects in humans.
Alfred Körblein
doaj +1 more source
Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?
Clinical Pharmacology &Therapeutics, EarlyView.Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart +6 more
wiley +1 more source