Results 61 to 70 of about 26,590 (258)

Did the French pregnancy pictogram change antiseizure medication use during pregnancy?

Epilepsia, EarlyView.
Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo, Christine Damase‐Michel, Marie Denuelle, Sébastien Boulogne, Laurane Delteil, Monica Saucedo, Catherine Deneux‐Tharaux, Isabelle Lacroix   +7 more
wiley   +1 more source

Estimation of embryotoxic and teratogenic effects of ivermectin in laboratory animals

Российский паразитологический журнал, 2016
Injection of ivermectin in a dose of 0,2 mg/kg to pregnant rates in critical stage of embryogenesis at days 1-6, 7-14 and 15-19 did not effect animals’ beha- vior.
N. B. Yemelyanova, N. A. Samoylovskaya
doaj  

Women with epilepsy: Evidence‐based counseling across the lifespan

Epilepsia, EarlyView.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn, Georgia Ramantani, Dominique Flügel, Verena Gaus, Susanne Schubert‐Bast, Elisabeth Sellitto, Jennifer Bausch, Bettina Schmitz   +7 more
wiley   +1 more source

Assessment of self-medication practices and safety profile of medicines utilisation among pregnant women attending antenatal clinics in Freetown, Sierra Leone: a multicentre cross-sectional study

Journal of Pharmaceutical Policy and Practice
Background Despite the potential foetal and maternal risks of self-medication, studies on self-medication practice and the safety profile of medicines used during pregnancy are scarce in our setting. This study determined the self-medication practice and
Onome Thomas Abiri, Shakiratu Lawal, Joshua Coker, James Baligeh Walter Russell, Ibrahim Franklyn Kamara, N’falie Ibrahim Sesay, Joseph Sam Kanu, Foday Umaro Turay, Michael Lahai, Henry Edward Clarence Carter, Mohamed Bawoh, Mohamed Samai   +11 more
doaj   +1 more source

Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos

Frontiers in Pharmacology, 2019
Angiogenesis is a crucial event for tumor progression and metastasis. It is the process through which new blood vessels are formed and has become a therapeutic target in many cancer therapies.
Annalisa Mercurio, Annalisa Mercurio, Lucy Sharples, Lucy Sharples, Filomena Corbo, Carlo Franchini, Angelo Vacca, Alessia Catalano, Alessia Carocci, Roger D. Kamm, Andrea Pavesi, Giulia Adriani, Giulia Adriani   +12 more
doaj   +1 more source

Timing of conception after methotrexate and subsequent pregnancy outcomes: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Methotrexate is widely used to treat ectopic pregnancy (EP). Concerns about its teratogenicity have led to uncertainty regarding the optimal interval before attempting conception. Guidelines recommend a 3‐month washout period, while the manufacturer advises 6 months. Evidence on the safety of early conception is limited.
Bar Rosh, Joul Hadad, Naomi Gronich
wiley   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

ASSESSMENT OF EFFECTS OF DRUGS AVERSECT FORTE AND AVERSECT COMBI ON EMBRYONIC DEVELOPMENT OF THE RAT

Российский паразитологический журнал, 2016
Objective of research: To estimate the effect of new combination drugs Aversect Forte and Aversect Combi on rats.Materials and methods: The present experiment for the evaluation of eventual embyotoxic and teratogenic properties of drugs Aversect Forte ...
M. V. Semenova, E. I. Koveshnikova
doaj   +1 more source