Results 71 to 80 of about 31,463 (288)

Reducing Exposure Before Birth: An Interrupted Time Series Study of Prenatal Exposure to Fetotoxic Medications Under Risk Management Plans in Canada

Clinical Pharmacology &Therapeutics, EarlyView.
Canada's 2009 risk management plan (RMP) framework has not been evaluated for prenatal exposure impact. Conversely, widely used drugs such as nonsteroidal anti‐inflammatory drugs (NSAIDs) lack RMPs. We assessed first‐trimester exposure to RMP‐regulated medications following regulatory interventions and to NSAIDs following safety publications.
Nahiyan Saiyara Khan, Odile Sheehy, Lisiane Freitas Leal, Vanina Tchuente, Anick Bérard   +4 more
wiley   +1 more source

Fluconazole-Associated Birth Defects: A Comprehensive Review

INNOVATIONS in Pharmacy, 2014
Background: The August 2013 publication of a large historical cohort study in the New England Journal of Medicine has reignited interest in the potential teratogenic effects of fluconazole when used in pregnant females.
Janssen M. Firth, Nicholas Daniel, Peter J. Hughes   +2 more
doaj   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Zebrafish embryotoxicity and teratogenic effects of Christia vespertilionis leaf extract

, 2022
Christia vespertilionis or butterfly wings is a traditional medicinal plant used to treat, among others, colds and bronchitis. The plant was also reported to be a remedy for cancer, with several products based on the plant becoming commercially available,
Norazhar, Anis Irfan, Mohd Faudzi, Siti Munirah, Wan Ibrahim, Wan Norhamidah, Shaari, Khozirah, Saleh Hodin, Nur Atikah   +4 more
core   +1 more source

Phase‐Change‐Activated Slippery Organogel Composite for All‐in‐One Anti‐Corrosion, Antifouling, and Self‐Cleaning

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A super‐slippery liquid‐infused composite organogel is engineered by localized interfacial grafting between hydrogel and oleogel networks, endowing the coating with a durable, multifunctional marine‐protective interface. Dynamic antifouling surfaces have emerged as a promising alternative, offering the potential for eco‐friendly and high‐performance ...
Mengsheng Xia, Chao Wang, Jiahao Ma, Jiwei Chen, Yixi Su, Junkai Gao, Weiqi Fu   +6 more
wiley   +1 more source

Teratogenic effects of cadmium on rat skin

, 1998
Cadmium is a well-known teratogen in laboratory animals. However, teratogenic effects of cadmium have not been well-described on skin. The purpose of the present study was to assess histologically the teratogenic effects of cadmium on rat skin. After two
İnalöz, Hüseyin Serhat, İnalöz, Serap S., Deveci, Engin   +2 more
core  

The second unprovoked seizure in a cohort of treated patients with a first unprovoked seizure

Epileptic Disorders, EarlyView.
Abstract Objectives To evaluate the rate of a second unprovoked seizure in antiseizure medications (ASMs)‐treated patients following a first unprovoked seizure and to identify potential risk factors associated with its occurrence. Methods A retrospective review of the computerized database and the medical records of all the patients who presented to ...
Revital Gandelman‐Marton, Jacques Theitler   +1 more
wiley   +1 more source

The outcomes of consecutive pregnancies in Australian women with epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective To investigate the extent to which seizure control and the occurrence of fetal malformation in an initial pregnancy can serve to anticipate the outcome in the next pregnancy. Methods We analyzed the records of the Raoul Wallenberg Australian Register of Antiepileptic Drugs in Pregnancy for seizure control and fetal malformation data ...
Frank Vajda, Terence J. O'Brien, Janet Graham, Alison Hitchcock, Piero Perucca, Cecilie Lander, Simon Vajda, Mervyn Eadie   +7 more
wiley   +1 more source

PREGNANT WOMEN USE OF TERATOGENIC PLANTS IN MOROCCO: A CROSS-SECTIONAL STUDY

Objectives. Congenital malformations originate from the genetic constitution of the embryo or from an extrinsic defect during its in-utero development.
Soukaina KANNANE, Samia BOUSSAA, Oulaid TOULOUN   +2 more
core   +1 more source

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

Epileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef   +10 more
wiley   +1 more source