Results 91 to 100 of about 31,463 (288)

Timing of conception after methotrexate and subsequent pregnancy outcomes: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Methotrexate is widely used to treat ectopic pregnancy (EP). Concerns about its teratogenicity have led to uncertainty regarding the optimal interval before attempting conception. Guidelines recommend a 3‐month washout period, while the manufacturer advises 6 months. Evidence on the safety of early conception is limited.
Bar Rosh, Joul Hadad, Naomi Gronich
wiley   +1 more source

The teratogenic effects of drugs (revision).

open access: yes, 1991
This booklet illustrates the effects that drugs have on a blastocyst and subsequent foetus development. The result from the action of drugs on the parents is briefly explored and a list of teratogenic drugs is given altough many have only been tested ...

core  

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

A REVIEW OF IRANIAN MEDICINAL PLANTS WITH TERATOGENIC AND ABORTION-INDUCING SIDE EFFECTS

open access: yes, 2017
Compounds with teratogenic effects can cause genetic defects during pregnancy and subsequently lead to unwanted abortions. Unwanted abortions and postnatal genetic defects can impose economic and psychological burden on the community.
Artimani, Tayebe.   +4 more
core  

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui   +2 more
wiley   +1 more source

Teratogenic Effects of Potassium bromate On Drosophila melanogaster

open access: yes
In recent years, there has been growing concern about the toxic potential of substances consumed by humans. One such substance that has attracted attention is potassium bromate (KBrO3) used as a food additive, water disinfectant, and in pharmaceutical ...
N. Shivanna, Jyoti Aiwale
core   +1 more source

Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim   +4 more
wiley   +1 more source

Preclinical testing of new domestic supramolecular complex of triclabendazole «Triclafascid» embryotrophic activity

open access: yesРоссийский паразитологический журнал, 2019
The purpose of the study: embryotoxic and teratogenic effects of a new domestic supramolecular complex of triclabendazole “Triclafascid”. Materials and methods.
M. V. Milenina, M. B. Musaev
doaj  

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos   +11 more
wiley   +1 more source

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

open access: yesJCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf   +5 more
wiley   +1 more source

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