Results 141 to 150 of about 48,551 (323)

Principles of teratogenicity [PDF]

An agent is now considered a teratogen if its administration to the pregnant mother causes, directly or indirectly structural or functional abnormalities in the fetus, or in the child after birth, which may not be apparent until later life.
McElhatton PR
core  

In Vivo Study of Diethylstilbestrol Teratogenicity on Mouse Embryo: Teratogenicity of diethylstilbestrol [PDF]

, 2005
Diethylstilbestrol (DES) was widely used in the past, as the morning after contraception, but its application became extremely limited due to several complications including delayed clear cell adenocarcinoma in female infants.
Etemadi, Behnaz, Marzban, Hassan, Sabzevari, Omid, Ostad, Syyed Nasser   +3 more
core   +1 more source

A challenging issue: Should medications be prescribed to pregnant and depressed women?

Psychiatry and Behavioral Sciences, 2011
Women have higher prevalence rates of depression than men and they are particularly vulnerable to depression in childbearing years. The rates of depression can reach up to 20% of all women during pregnancy. Actually, physicians who treat women are likely
Nazan Aydın, Elif Oral, Mustafa Gulec
doaj   +1 more source

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

Use of Prescribed Psychotropics during Pregnancy: A Systematic Review of Pregnancy, Neonatal, and Childhood Outcomes

Brain Sciences, 2019
This paper reviews the findings from preclinical animal and human clinical research investigating maternal/fetal, neonatal, and child neurodevelopmental outcomes following prenatal exposure to psychotropic drugs.
Catherine E. Creeley, Lisa K. Denton
doaj   +1 more source

Assessing the hidden risks of non‐thermal processing: Ultrasound‐induced toxicity of cashew apple juice in a zebrafish model

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background High‐intensity ultrasound is widely advocated for the preservation of liquid foods; however, the potential formation or release of toxic compounds during processing remains under‐investigated. This study evaluated the toxicological profile of cashew apple juice processed by high‐intensity ultrasound (1250, 1875, and 2500 W;L⁻¹ ...
Thaiz Batista Azevedo Rangel Miguel, Sergimar Kennedy de Paiva Pinheiro, Jorge Henrique de Andrade Vieira, Fabiano André Narciso Fernandes, Sueli Rodrigues, Emilio de Castro Miguel   +5 more
wiley   +1 more source

Managing Skin Diseases During Pregnancy: Treatment Discontinuation, Concerns and Physician Counselling

JEADV Clinical Practice, EarlyView.
Physiological changes during pregnancy can trigger or worsen dermatological conditions, yet evidence‐based guidance for safe management remains limited. In a cross‐sectional survey of 273 pregnant women, 33.7% reported having a skin disease, and 56% experienced worsening of symptoms.
Frederikke Seeberg, Anne Sofie Frølunde, Mette Deleuran, Line Kolding, Christian Vestergaard   +4 more
wiley   +1 more source

Prerequisites and limitations of the use of oral anticoagulants in pregnant women in real-world clinical practice

Реальная клиническая практика: данные и доказательства
Relevance. Anticoagulants are commonly used during pregnancy is a fairly common practice. Due to the widespread use of oral anticoagulants in real practice and the high frequency of unplanned pregnancy, physicians should assess the risks and plan ...
Kh. A. Zagorodnikova, O. A. Bettikher, I. Ye. Zazerskaya   +2 more
doaj   +1 more source

Sodium sulfite can reliably induce chemical hypoxia without toxic effects in the model sea anemone species, Exaiptasia diaphana

Limnology and Oceanography: Methods, EarlyView.
Abstract Climate change is accelerating the deoxygenation of aquatic ecosystems, so understanding its effects on biological processes is increasingly critical. An emerging method for inducing hypoxia during experimentation utilizes sodium sulfite (SSI) to scavenge oxygen; however, it remains unclear if hypoxia‐inducing concentrations of SSI are toxic ...
Zhen Qin, Lorenzo Vassura, Bianca A. Parodi, Elise M. J. Laetz   +3 more
wiley   +1 more source

Scientific opinion on the tolerable upper intake level for preformed vitamin A and β‐carotene

EFSA Journal
Following two requests from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the revision of the tolerable upper intake level (UL) for preformed vitamin A and β ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan de Henauw, Karen‐Ildico Hirsch‐Ernst, Helle Katrine Knutsen, Alexandre Maciuk, Inge Mangelsdorf, Harry J. McArdle, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Georg Lietz, Giovanni Passeri, Ionut Craciun, Lucia Fabiani, Zsuzsanna Horvath, Silvia Valtueña Martínez, Androniki Naska   +21 more
doaj   +1 more source