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Detection of Thalidomide Embryotoxicity by In Vitro Embryotoxicity Testing Based on Human iPS Cells
The mouse embryonic stem cell test (mEST) is used to assess the embryotoxicity of drug candidates by evaluating the effects on the cardiac differentiation of stem cells. However, thalidomide embryotoxicity has not yet been reported using the mEST.
Nobuo Aikawa +5 more
exaly +6 more sources
Rearing Sea Urchins to Promote ‘Ready-to-Spawn’ Conditions for Ecotoxicological Surveys [PDF]
The sea urchin Paracentrotus lividus is a good model in ecotoxicology, but adults living along the Italian coasts have a limited reproductive period.
Roberta Miroglio +7 more
doaj +2 more sources
Toxicological Effects of Glufosinate-Ammonium-Containing Commercial Formulations on Biomphalaria glabrata in Aquatic Environments: A Multidimensional Study from Embryotoxicity to Histopathology [PDF]
Glufosinate-ammonium (GLA) is a broad-spectrum herbicide widely used for weed control. However, its potential toxic effects on non-target aquatic organisms, especially in freshwater ecosystems, are of growing concern.
Yuncheng Qian +9 more
doaj +2 more sources
Prodigiosins (prodiginines) are a class of bacterial secondary metabolites with remarkable biological activities and color. In this study, optimized production, purification, and characterization of prodigiosin (PG) from easily accessible Serratia ...
Jelena Lazic +8 more
doaj +1 more source
Introduction. Combination antiretroviral therapy is currently the main component of treatment for human immunodeficiency virus (HIV) infected patients.
E. A. Gaidai +7 more
doaj +1 more source
The overview of current evidence on the reproductive toxicity of dibutyl phthalate
Over the past years, many legitimate concerns have been raised about the effects of dibutyl phthalate (DBP) as an endocrine disruptor, especially on reproduction.
Ewelina Czubacka +2 more
doaj +1 more source
The Embryotoxicity of Some Phenol Derivatives on Zebrafish, Danio rerio [PDF]
The existence of toxicants in ecosystems has been increased dramatically in recent years, especially in aquatic environments. Phenols and chlorinated phenol derivatives are toxic industrial compounds. Phenols and derivatives are known to be environmental
Z Ceylan, T Sisman, H Dane, Ş Adil
doaj +1 more source
Iphiona mucronata (Family Asteraceae) is widely distributed in the Eastern desert of Egypt. It is a promising plant material for phytochemical analysis and pharmacologic studies, and so far, its specific metabolites and biological activity have not yet ...
Łukasz Pecio +9 more
doaj +1 more source
Determination of embryotoxic dose limit of detomidine with in-ovo model [PDF]
Aim: The aim of this study is to determine the embryotoxic dose limit of detomidine with an in-ovo model using fertile hen?s eggs. Materials and Methods: 210 fertile eggs were divided into 7 equal (n: 30) groups and placed in the incubator under optimum ...
Rahmi Canbar +3 more
doaj
The embryotoxicity of gossypol [PDF]
AbstractIn utero development was analyzed in pregnancies that resulted from matings between gossypol‐treated male rats and untreated female rats and in pregnancies in which gossypol was administered to the pregnant rat only. Gossypol treatment of males had no effect on the outcome of pregnancy.
openaire +3 more sources

