Results 11 to 20 of about 4,182 (225)
Embryotoxicity assays for leached components from dental restorative materials [PDF]
Background Currently, there are no suitable assays available to evaluate the embryotoxicity of leached components from restorative dental materials. Methods The effect of the medium conditioned by composites and amalgam on mouse blastocysts in vitro was ...
Mummolo Stefano +8 more
doaj +3 more sources
Development of technique for in vitro embryotoxicity of dental biomaterials
The Embryonic Stem Cell Test (EST) developed in Germany in 1997 is known as a screening test method capable of predicting the presence of unknown chemicals influencing normal human development.
Koichi Imai, D.D.S., Ph.D.
doaj +2 more sources
Preclinical studies in rodents have demonstrated that artemisinins, especially injectable artesunate, can induce fetal death and congenital malformations at a low dose range.
Qigui Li, Peter J. Weina
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Background Gibberellic acid (GA3) is a plant growth regulator used to improve the quality of crops but its residues in food causes many hazardous effects.
El-Sabry Abu Amra +3 more
doaj +1 more source
Currents, wave motion, solar radiation, and abrasion are mechanisms responsible for the degradation of large plastic artifacts and contribute to the dispersion of micro and nanoplastics into aquatic ecosystems, which are, currently, the most dangerous ...
Martina Contino +6 more
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Chloroquine embryotoxicity in the postimplantation rat conceptus in vitro [PDF]
The embryotoxicity of the antimalarial drug chloroquine (CQ) was evaluated in vitro using the rat whole embryo culture system. CQ was found to be embryotoxic and dysmorphogenic when added directly to the culture media containing gestational day (GD) 10 ...
Ambroso, Jeffrey L. +3 more
core +1 more source
EMBRYOTOXIC AND TERATOGENIC EFFECT OF DISODIUM GLYCYRRHETINIC ACID HEMIPHTHALATE IN MICE [PDF]
Disodium glycyrrhetinic acid hemiphthalaic (GAP) was evaluated for developmental toxicity in pregnant NMRI mice. GAP was administered intrapcritoneally on days S, 9, 10, of gestation at doses of 0, 25, 50 and 75 mg/kg/dav.
H. Marzbnn
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In ovo injection of nutrients can modulate the embryo’s physiological responses against aflatoxin B1 (AFB1) embryotoxicity. This hypothesis was tested using in ovo injection of Arctostaphylos uva-ursi (Ar. uu.) methanolic extract.
Hamada Elwan +3 more
doaj +1 more source
Ketoconazole and fluconazole are two broad-spectrum azole antifungals used for the treatment of superficial and systemic mycoses. Embryotoxicity and teratogenicity have been reported in some studies when those drugs are administered at high doses to ...
Vanessa Cristiane de Santana Amaral +1 more
doaj +1 more source
Background: Kratom (Mitragyna speciosa Korth), a popular opioid-like plant holds its therapeutic potential in pain management and opioid dependence. However, there are growing concerns about the safety or potential toxicity risk of kratom after prolonged
Thenmoly Damodaran +4 more
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