Results 11 to 20 of about 4,182 (225)

Embryotoxicity assays for leached components from dental restorative materials [PDF]

open access: yesReproductive Biology and Endocrinology, 2011
Background Currently, there are no suitable assays available to evaluate the embryotoxicity of leached components from restorative dental materials. Methods The effect of the medium conditioned by composites and amalgam on mouse blastocysts in vitro was ...
Mummolo Stefano   +8 more
doaj   +3 more sources

Development of technique for in vitro embryotoxicity of dental biomaterials

open access: yesJapanese Dental Science Review, 2016
The Embryonic Stem Cell Test (EST) developed in Germany in 1997 is known as a screening test method capable of predicting the presence of unknown chemicals influencing normal human development.
Koichi Imai, D.D.S., Ph.D.
doaj   +2 more sources

Severe Embryotoxicity of Artemisinin Derivatives in Experimental Animals, but Possibly Safe in Pregnant Women

open access: yesMolecules, 2009
Preclinical studies in rodents have demonstrated that artemisinins, especially injectable artesunate, can induce fetal death and congenital malformations at a low dose range.
Qigui Li, Peter J. Weina
doaj   +2 more sources

The protective role of olive oil against gibberellic acid-induced embryotoxicity at prenatal stages of mice

open access: yesJournal of Basic and Applied Zoology, 2020
Background Gibberellic acid (GA3) is a plant growth regulator used to improve the quality of crops but its residues in food causes many hazardous effects.
El-Sabry Abu Amra   +3 more
doaj   +1 more source

Sublethal Effects of Polystyrene Nanoplastics on the Embryonic Development of Artemia salina (Linnaeus, 1758)

open access: yesAnimals, 2023
Currents, wave motion, solar radiation, and abrasion are mechanisms responsible for the degradation of large plastic artifacts and contribute to the dispersion of micro and nanoplastics into aquatic ecosystems, which are, currently, the most dangerous ...
Martina Contino   +6 more
doaj   +1 more source

Chloroquine embryotoxicity in the postimplantation rat conceptus in vitro [PDF]

open access: yes, 1993
The embryotoxicity of the antimalarial drug chloroquine (CQ) was evaluated in vitro using the rat whole embryo culture system. CQ was found to be embryotoxic and dysmorphogenic when added directly to the culture media containing gestational day (GD) 10 ...
Ambroso, Jeffrey L.   +3 more
core   +1 more source

EMBRYOTOXIC AND TERATOGENIC EFFECT OF DISODIUM GLYCYRRHETINIC ACID HEMIPHTHALATE IN MICE [PDF]

open access: yesActa Medica Iranica, 1998
Disodium glycyrrhetinic acid hemiphthalaic (GAP) was evaluated for developmental toxicity in pregnant NMRI mice. GAP was administered intrapcritoneally on days S, 9, 10, of gestation at doses of 0, 25, 50 and 75 mg/kg/dav.
H. Marzbnn
doaj   +2 more sources

Modulatory Effects of Arctostaphylos uva-urs Extract In Ovo Injected into Broiler Embryos Contaminated by Aflatoxin B1

open access: yesAnimals, 2022
In ovo injection of nutrients can modulate the embryo’s physiological responses against aflatoxin B1 (AFB1) embryotoxicity. This hypothesis was tested using in ovo injection of Arctostaphylos uva-ursi (Ar. uu.) methanolic extract.
Hamada Elwan   +3 more
doaj   +1 more source

Ketoconazole- and fluconazole-induced embryotoxicity and skeletal anomalies in wistar rats: a comparative study

open access: yesBrazilian Archives of Biology and Technology, 2008
Ketoconazole and fluconazole are two broad-spectrum azole antifungals used for the treatment of superficial and systemic mycoses. Embryotoxicity and teratogenicity have been reported in some studies when those drugs are administered at high doses to ...
Vanessa Cristiane de Santana Amaral   +1 more
doaj   +1 more source

Comparative Toxicity Assessment of Kratom Decoction, Mitragynine and Speciociliatine Versus Morphine on Zebrafish (Danio rerio) Embryos

open access: yesFrontiers in Pharmacology, 2021
Background: Kratom (Mitragyna speciosa Korth), a popular opioid-like plant holds its therapeutic potential in pain management and opioid dependence. However, there are growing concerns about the safety or potential toxicity risk of kratom after prolonged
Thenmoly Damodaran   +4 more
doaj   +1 more source

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