Results 31 to 40 of about 4,182 (225)

Phytochemical and Safety Evaluations of Volatile Terpenoids from Zingiber cassumunar Roxb. on Mature Carp Peripheral Blood Mononuclear Cells and Embryonic Zebrafish

open access: yesMolecules, 2020
Pharmaceutical products of essential oil from Zingiber cassumunar Roxb. are extensively being developed, while the research on their safety is seldom documented.
Raktham Mektrirat   +4 more
doaj   +1 more source

Effects of embryonic exposure to chromium (VI) on blood parameters and liver microstructure of 1-day-old chickens

open access: yesPoultry Science, 2021
Hexavalent chromium (Cr(VI)) has carcinogenic, nephrotoxic, hepatotoxic, and neurotoxic effects. Exposure to Cr(VI) can also lead to hematological alterations and blood biochemical changes. The literature on Cr(VI) toxicity concerns mostly adult forms of
Bartosz Bojarski   +7 more
doaj   +1 more source

Implantation‐On‐Chip: An AI‐Based Platform for Monitoring the Embryo Trophoblast–Endometrial Stroma Cross Talk With Xenobiotics Interference

open access: yesAdvanced Intelligent Systems, EarlyView.
We present a novel AI‐integrated implantation‐on‐chip platform that enables mimicking and monitoring the maternal–fetal interactions at the early phases of human embryo implantation with high spatiotemporal resolution. The complexity of the trophoblast invasion process was addressed by conducting the analysis at global (rate of invasion) and local ...
Joanna Filippi   +12 more
wiley   +1 more source

Assessing the Impact of Chrysene-Sorbed Polystyrene Microplastics on Different Life Stages of the Mediterranean Mussel Mytilus galloprovincialis

open access: yesApplied Sciences, 2021
The sorption of organic pollutants to marine plastic litter may pose risks to marine organisms, notably for what concerns their intake and transfer through microplastic (MP) ingestion.
Marco Capolupo   +5 more
doaj   +1 more source

Timing of conception after methotrexate and subsequent pregnancy outcomes: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Methotrexate is widely used to treat ectopic pregnancy (EP). Concerns about its teratogenicity have led to uncertainty regarding the optimal interval before attempting conception. Guidelines recommend a 3‐month washout period, while the manufacturer advises 6 months. Evidence on the safety of early conception is limited.
Bar Rosh, Joul Hadad, Naomi Gronich
wiley   +1 more source

Embryotoxicity of human sera from patients treated with isotretinoin

open access: yes, 1993
Sera of 20 patients treated with 20-40 mg isotretinoin/day were tested for embryotoxicity potential. For each patient, the first sample was taken before treatment (control sample) and the second was taken 2 months after the start of treatment (treated ...
Despontin, Karine   +10 more
core   +1 more source

Protein Biomarkers for in Vitro Testing of Embryotoxicity

open access: yes, 2016
There are new challenges for hazard and risk assessment in the chemical industry with regard to REACH legislation in Europe and related activities in the U.S.
Andrea Seiler (2254906)   +16 more
core   +4 more sources

Barbatic Acid Offers a New Possibility for Control of Biomphalaria Glabrata and Schistosomiasis

open access: yesMolecules, 2017
This study evaluated the biological activity of an ether extract and barbatic acid (BAR) from Cladia aggregata on embryos and adult mollusks of Biomphalaria glabrata, cercariae of Schistosoma mansoni and the microcrustacean Artemia salina.
Mônica Cristina Barroso Martins   +9 more
doaj   +1 more source

The influence of the water-salt extract of the medicinal leech Hirudo verbana Carena, 1820 on the general course of embryogenesis in rats after intraperitoneal administration

open access: yesБіологічні студії, 2023
Background. The increase in infectious and non-infectious diseases occurrence during pregnancy prompts scientists to search for substances that can fight these ailments.
Ruslan Aminov
doaj   +1 more source

Percutaneous Retinoid Absorption and Embryotoxicity

open access: yesJournal of Investigative Dermatology, 1990
A single application of 17 micrograms/kg or 8.7 mg/kg all-trans-[10,11-3H2]-retinoic acid dissolved in acetone to shaved dorsal hamster skin resulted in rapid absorption and dose-dependent rates of elimination. An equation describing a two-compartment open model with a very brief lag time and first-order uptake and elimination was used to describe the ...
Willhite, Calvin C   +3 more
openaire   +2 more sources

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