Results 51 to 60 of about 2,310 (177)

Decrease of intercellular pH as possible mechanism of action of embryotoxicity of glycol ether alkoxyacetic acid metabolites

, 2010
Embryotoxicity of glycol ethers is caused by their alkoxyacetic acid metabolites, but the mechanism underlying the embryotoxicity of these acid metabolites is so far not known.
Verwei, M., Blaauboer, B.J., Dep IRAS, Rietjens, I.M.C.M., Louisse, J., Risk Assessment of Toxic and Immunomodulatory Agents, Bai, Y., van de Sandt, J.J.M., Yanquin Bai, Sandt, J.J.M., van de, Rietjens, I., Johannes J.M. van de Sandt, Yanqing Bai, Miriam Verwei, Jochem Louisse, Bas J. Blaauboer, Ivonne M.C.M. Rietjens   +16 more
core   +1 more source

Chemical Composition, In Vitro Antitumor Effect, and Toxicity in Zebrafish of the Essential Oil from Conyza bonariensis (L.) Cronquist (Asteraceae)

Biomolecules, 2023
The essential oil from Conyza bonariensis (Asteraceae) aerial parts (CBEO) was extracted by hydrodistillation in a Clevenger-type apparatus and was characterized by gas chromatography–mass spectrometry. The antitumor potential was evaluated against human
Rafael Carlos Ferreira, Yuri Mangueira do Nascimento, Paulo Bruno de Araújo Loureiro, Rafael Xavier Martins, Maria Eduarda de Souza Maia, Davi Felipe Farias, Josean Fechine Tavares, Juan Carlos Ramos Gonçalves, Marcelo Sobral da Silva, Marianna Vieira Sobral   +9 more
doaj   +1 more source

Developmental Toxicity Study for the Antimalarial Drug Combination Cabamiquine‐Pyronaridine Using a Translational Approach

Birth Defects Research, Volume 118, Issue 10, October 2026.
ABSTRACT Background The safety of pharmacological treatments during pregnancy is a significant concern, as many medications lack comprehensive reproductive safety data. This creates gaps in therapeutic options for pregnant women, particularly malaria, which poses serious risks to maternal and fetal health.
Wookyung Kim, Geum‐Sil Cho, Andreas Gado, Tobias Hyun Ho Baeurle, Habib Karimi, Filippo Venezia, Claude Oeuvray, Thomas Spangenberg, Sebastian G. Wicha, Claudia Demarta‐Gatsi   +9 more
wiley   +1 more source

Determination of Embryotoxic effects of Atipamezole using in ovo model

Revista Científica, 2023
Atipamezole is a specific α2-adrenergic receptor antagonist, and there exists insufficient information on its use during pregnancy. The aim of this study was to determine the embryotoxic activity of Atipamezole through an in ovo method. During the first
Rahmi Canbar, Muhittin Uslu, Mustafa Sedat Arslan, Harun Kızılay   +3 more
doaj   +1 more source

Advances in Agricultural Applications of Lignans

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This graphical abstract presents lignans as green alternatives to chemical pesticides and antibiotics for agriculture and veterinary use. It illustrates their applications in plant protection (antifungal, insecticidal, herbicidal, fruit preservation) and aquaculture, classifies lignan subtypes from classic to complex forms, highlights limitations like ...
Kaida Li, Huawen Wang, Xiangjie Luo, Feng Hao, Kun Wei, Le Cai   +5 more
wiley   +1 more source

Spermiotoxicity and embryotoxicity of permethrin in the sea urchin paracentrotus lividus

, 2015
WOS: 000350874900003PubMed: 25634326The toxicity of permethrin on the fertilization and early development of sea urchin Paracentrotus lividus embryos were studied. Spermiotoxicity was evaluated on the basis of fertilization rate.
Erkmen, Belda
core   +1 more source

Embryotoxicity Assay of Aflatoxin Produced by Aspergillus Parasiticus NRRL 2999 [PDF]

, 2000
1. The embryotoxicity of mixed aflatoxins (AF) and aflatoxin B-1 (AFB(1)) were evaluated by a modified chick embryotoxicity screening test (CHEST). Adverse effects on the early embryonic development of thymus and bursa of Fabricius were also investigated
Boydak, M., Demet, O., Dönmez, H. H., Nizamlıoğlu, F., Oğuz, H., Sur, E., Çelik, İ., Celik, I, Sur, E, Dönmez, HH, Demet, Ö, Oguz, H, Boydak, M, Nizamlioglu, F   +13 more
core   +1 more source

Dual Antiviral and Immunomodulatory Effects of Phytochemicals in Influenza A Virus Infection: Targeting Key Host Signaling Pathways

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Influenza A virus modulates host innate immune pathways, including TLR, RIG‐I, MAPK, and NF‐κB signaling, to support replication and drive inflammatory pathology. Plant‐derived phytocompounds target these interconnected pathways, offering a potential host‐directed immunomodulatory approach complementary to conventional antivirals.
Dibakar Chowdhury, Hillary A. Vanderven, Phurpa Wangchuk, Subir Sarker   +3 more
wiley   +1 more source

Protein Biomarkers for in Vitro Testing of Embryotoxicity

, 2016
There are new challenges for hazard and risk assessment in the chemical industry with regard to REACH legislation in Europe and related activities in the U.S.
Andrea Seiler (2254906), André Schrattenholz (2254882), Rainer Schöpf (2254912), Martina Klemm-Manns (2254891), Annelieke K. Peters (2254909), Chaturvedala Sastri (2254915), Katrin Hayess (2254879), Margino Steemans (2254918), Werner Stegmann (2254873), Karlfried Groebe (2254876), Petra Jaeckel (2254894), Slobodan Poznanovic (2254900), Horst Spielmann (2254888), Gerhard Schwall (2254885), Woijciech Wozny (2254870), Tina C. Stummann (2254897), Helmut Zengerling (2254903)   +16 more
core   +4 more sources

Mesodermal Dysmorphogenesis of Ginsenosides: An Experimental Study

Journal of Shalamar Medical & Dental College, 2019
Background: The versatile and dynamic activities of Panax Ginseng are attributed to its active components. They are readily available over the counter and are known for their effects as an aphrodisiac & health building; in addition, they are given ...
Uzma Daud, Qasim Muneer, Javeria Noor, Fahad Raza, Sarah Khalid   +4 more
doaj   +1 more source