Results 61 to 70 of about 2,310 (177)
Hydroxypropyl‐β‐cyclodextrin (HPβCD)–N,N‐diethyl‐meta‐toluamide (DEET) complex extended tick repellency to 168 h. Full protection against Aedes aegypti for 7 h with HPβCD‐DEET. HPβCD reduced DEET release and skin retention significantly. No embryotoxicity observed below 325 mg L−1 in zebrafish model.
Gessyka Rayana Silva Pereira +10 more
wiley +1 more source
Embryotoxicity Caused by DON-Induced Oxidative Stress Mediated by Nrf2/HO-1 Pathway
Deoxynivalenol (DON) belongs to the type B group of trichothecenes family, which is composed of sesquiterpenoid metabolites produced by Fusarium and other fungi in grain.
Hanyin Wang +11 more
core +1 more source
We present a novel AI‐integrated implantation‐on‐chip platform that enables mimicking and monitoring the maternal–fetal interactions at the early phases of human embryo implantation with high spatiotemporal resolution. The complexity of the trophoblast invasion process was addressed by conducting the analysis at global (rate of invasion) and local ...
Joanna Filippi +12 more
wiley +1 more source
Albendazole : a comparison of relay embryotoxicity with embryotoxicity of individual metabolites.
By using an experimental model compound (Albendazole, an anthelmintic) the authors compared two methodologies for the toxicological evaluation of bovine hepatic residues. Toxicity was not demonstrated for bovine hepatic residues in a relay embryotoxicity study in the rat.
Delatour, P., Parish, R.C., Gyurik, R.J.
openaire +2 more sources
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang +7 more
wiley +1 more source
Recent, substantial declines in blue mussel (Mytilus edulis) beds in northern European estuaries signal an urgent need to unravel how chronic contaminant exposure, climate-driven warming and salinity shifts jointly affect the development and survival of ...
Isabella M. Jackson +4 more
doaj +1 more source
Nano‐immunostimulants improve fish health through targeted and controlled delivery of immunostimulatory compounds. Biodegradable polymeric and lipid‐based nanocarriers enhance immune responses, bioavailability and disease resistance while reducing antibiotic dependence and environmental impact.
Mustafa Öz, Enes Üstüner
wiley +1 more source
Metabonomic Phenotyping Reveals an Embryotoxicity of Deca-Brominated Diphenyl Ether in Mice
Recent studies have demonstrated that polybrominated diphenyl ethers (PBDEs), a group of industrial chemicals, could disrupt thyroid hormone homeostasis and exhibit neurotoxicity, reproductive toxicity, and embryotoxicity.
Xin Qi (177590) +12 more
core +1 more source
EVALUATION OF EMBRYOTROPIC PROPERTIES OF THE ANTHELMINTIC MITRANOX
Objective of research: to estimate the potential embryotropic properties of the anthelmintic Mitranox. Materials and methods: the experiments were conducted on 70 white outbreed pregnant rats divided into one control and 6 experimental groups (10 animals
S. A. Kozlov, M. B Musaev
doaj +1 more source
Cancer survivorship in malignant melanoma
Summary Robust long‐term survival data have transformed the prognosis of metastatic melanoma. For combination therapy with immune checkpoint inhibitors (ICIs), 10‐year melanoma‐specific survival rates now exceed 50 %, and durable disease control is achievable in a substantial proportion of patients, including those with brain metastases.
Markus Reitmajer +15 more
wiley +1 more source

