Effect of Anti‐IL‐23 and Anti‐IL‐17 Therapy on Darier Disease: A Case Series
ABSTRACT Darier disease is a rare ATP2A2‐related genodermatosis for which therapeutic options remain limited, as acitretin is often constrained by toxicity and teratogenicity. In this retrospective real‐world case series of eight patients, anti‐IL‐17 therapy showed a more consistent early signal of clinical benefit than anti‐IL‐23 therapy, with greater
Maione Vincenzo +6 more
wiley +1 more source
Exclusion by Design: Regulatory Reform and Evolving Frameworks for Clinical Trials in Pregnancy. [PDF]
Kearns GL, Saint-Raymond A.
europepmc +1 more source
Multiple cardiac malformations in a calf
This paper describes the morphopathological aspects of a case of multiple cardiac malformations in a calf. A two‐day‐old male calf of undefined breed was born with an ectopic heart, presenting with dyspnoea and in lateral recumbency. The owner had repositioned the exposed heart beneath the adjacent skin, which was suclosed, without additional incisions
LA Soares +7 more
wiley +1 more source
Gastrointestinal malignancies in pregnancy: practical considerations. [PDF]
Anderson C, Benson AB.
europepmc +1 more source
Sickle cell anaemia with and without crises: An observational study of pregnancy outcomes
Summary We assessed the pregnancy outcomes of patients with sickle cell crises. We carried out a retrospective study of 2 698 556 pregnancies in Quebec, Canada between 1989 and 2022. The primary exposure was sickle cell anaemia with crisis during or outside of pregnancy. Outcomes included severe maternal morbidity and other pregnancy complications.
Nathalie Auger +8 more
wiley +1 more source
Safety and efficacy of major antiviral and immune therapies in pregnancy for maternal viral infections: evidence synthesis of maternal and neonatal outcomes. [PDF]
Sleman S +4 more
europepmc +1 more source
Topical retinoids and risk of major congenital malformations and spontaneous abortion: a systematic review and meta-analysis. [PDF]
Alali AB +9 more
europepmc +1 more source
How we treat venous thromboembolism in pregnancy in a resource‐limited setting
HemaSphere, Volume 10, Issue 11, November 2026.
Theresa Nwagha +5 more
wiley +1 more source
Teratogenic Effects and Outcomes of Congenital Oropouche Virus Infection: Current Evidence, Pathophysiological Mechanisms, and Research Priorities. [PDF]
Pomar L, Epelboin L, Hcini N.
europepmc +1 more source

