Results 191 to 200 of about 21,579 (291)

A Rare Constellation of Omphalocele, Myelomeningocele, and Encephalocele in a Neonate Born to a Mother With Type 2 Diabetes Mellitus: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Pre‐gestational diabetes with reported poor glycemic control may be associated with rare and severe multiple congenital anomalies, such as omphalocele and multiple concurrent neural tube defects (NTDs). Early antenatal screening, strict maternal glycemic control, and multidisciplinary neonatal management are crucial to improving outcomes.
Jaber Hamad Jaber Amin   +5 more
wiley   +1 more source

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1169-1172, November 2026.
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart   +6 more
wiley   +1 more source

Pediatric Developmental Safety Assessment and New Approach Methodologies: US FDA/Triangle CERSI Workshop Report

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1240-1249, November 2026.
Pediatric developmental safety assessment presents distinct challenges in drug development. Children undergo dynamic changes in organ systems and drug disposition pathways during development, and drug‐related effects may be delayed or manifested differently than in adults.
Gilbert J. Burckart   +16 more
wiley   +1 more source

Management of advanced mycosis fungoides and Sézary Syndrome: International Recommendations for systemic treatments and allogeneic hematopoietic cell transplantation from the European Hematology Association, the EORTC Cutaneous Lymphoma Tumours Group, the International Society for Cutaneous Lymphoma, and the Lymphoma Working Party of the EBMT

open access: yesHemaSphere, Volume 10, Issue 11, November 2026.
Abstract Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are the most aggressive forms of cutaneous T‐cell lymphoma and remain associated with a poor prognosis and heterogeneous therapeutic approaches. Recent advances, including targeted therapies and improved transplant strategies, have substantially expanded treatment options, highlighting ...
Francesco Onida   +29 more
wiley   +1 more source

A Comprehensive Toxicological Safety Assessment of Superoxide Dismutase as a Novel Food Ingredient. [PDF]

open access: yesJ Toxicol
Chen D   +11 more
europepmc   +1 more source

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