ABSTRACT Pre‐gestational diabetes with reported poor glycemic control may be associated with rare and severe multiple congenital anomalies, such as omphalocele and multiple concurrent neural tube defects (NTDs). Early antenatal screening, strict maternal glycemic control, and multidisciplinary neonatal management are crucial to improving outcomes.
Jaber Hamad Jaber Amin +5 more
wiley +1 more source
Peripartum Management of Vagus Nerve Stimulation and Antiseizure Medications During Two Pregnancies in a Woman With Drug-Resistant Epilepsy: A Case Report. [PDF]
Ono M +5 more
europepmc +1 more source
Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart +6 more
wiley +1 more source
Compliance of Dermatologists in Kerala with International Pregnancy Prevention Prescription Guidelines of Isotretinoin: A Cross-Sectional Survey. [PDF]
Muhammed Kutty S +3 more
europepmc +1 more source
Pediatric developmental safety assessment presents distinct challenges in drug development. Children undergo dynamic changes in organ systems and drug disposition pathways during development, and drug‐related effects may be delayed or manifested differently than in adults.
Gilbert J. Burckart +16 more
wiley +1 more source
Squamocin as the Principal Toxic Constituent of <i>Annona squamosa</i> Seeds: Toxicity-Guided Isolation, Developmental and Neurotoxicity, and Metabolic Perturbations. [PDF]
Qi C +5 more
europepmc +1 more source
Abstract Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are the most aggressive forms of cutaneous T‐cell lymphoma and remain associated with a poor prognosis and heterogeneous therapeutic approaches. Recent advances, including targeted therapies and improved transplant strategies, have substantially expanded treatment options, highlighting ...
Francesco Onida +29 more
wiley +1 more source
A Comprehensive Toxicological Safety Assessment of Superoxide Dismutase as a Novel Food Ingredient. [PDF]
Chen D +11 more
europepmc +1 more source
Fertility treatment using assisted reproductive technology during immune checkpoint inhibition: report of two cases. [PDF]
Tomechko K +4 more
europepmc +1 more source

