Results 171 to 180 of about 48,551 (323)

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Transmasculine pregnancy—Occurrence, associations, and outcomes: A quantitative systematic review

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This quantitative systematic review of 44 studies shows that a significant minority of transmasculine people become pregnant, including after transition. Miscarriage and postnatal depression rates appeared high, but there was minimal information on most other important outcomes, demonstrating that more research is needed.
Catherine Meads, Chelsea Daniels, Shawn Walker, Susan Bewley   +3 more
wiley   +1 more source

EMBRYOTROPIC PROPERTIES OF A NEW COMPOSITION OF FENBENDAZOLE AND ALBENDAZOLE (PANAVERM PLUS)

Российский паразитологический журнал, 2016
The drug Panaverm plus administered at the doses of 10,0; 15,0; 25,0; 35,0 and 45,0 mg/kg body weight (by 4.5 times increased dose) showed no embryotropic activity.
A. M. Bittirov, S. J. Begiev, A. A. Bittirova, S. Sh. Kabardiev, L. H. Eldarova, Z. G. Musayev   +5 more
doaj  

Abortion—A brief description of the evolution of methods

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Termination of pregnancy is not a “modern” societal issue, but one that has been afforded to women, albeit with varying degrees of success, over many centuries. Methods have evolved which have increased the availability, effectiveness, and safety of abortion, while substantially reducing associated morbidity.
Laura Slade, Andrea Deussen, Jodie Dodd
wiley   +1 more source

Genotype‐directed therapy for non–small cell lung cancer diagnosed during pregnancy: A pooled analysis of seven cases from the Cancer and Pregnancy Registry with maternal and neonatal outcomes and review of the literature

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this retrospective case series from a single database of pregnant women with cancer, seven were diagnosed with non‐small cell lung cancer (NSCLC). Chemotherapy and in some cases also biomarker‐directed therapy during pregnancy were associated with disease control allowing delivery closer to term and resulting in improved maternal outcomes compared ...
Reed Firestone, Elyce Cardonick
wiley   +1 more source

Cereblon as a gateway for pharmacologically induced teratogenicity [PDF]

, 2015
In the public perception, thalidomide mainly evokes children with stunted limbs. Less known is its ongoing importance for treating multiple myeloma and leprosy. Interest in its further pharmacological development thus remains high, but is hindered by the
Boichenko, I. ; https://orcid.org/, Zhu, H. ; https://orcid.org/, Lupas, A. ; https://orcid.org/, Coles, M. ; https://orcid.org/, Zanini, F. ; https://orcid.org/, Hartmann, M. ; https://orcid.org/, Korycinski, M., Hernandez Alvarez, B. ; https://orcid.org/   +7 more
core  

The Health, Wellbeing and Health Service Use of Women Attempting or Planning Pregnancy: A Nationwide Cross‐Sectional Survey of Australian Women

Birth, EarlyView.
ABSTRACT Background Health and wellbeing during the preconception period influence maternal and child health outcomes. We describe the sociodemographic and health characteristics of Australian women currently attempting pregnancy or planning to conceive in the next 12 months, compared with other women of reproductive age, to identify opportunities for ...
Amie Steel, Danielle Schoenaker, Joanna Harnett, Jon Adams   +3 more
wiley   +1 more source

S3 guideline diagnostics and therapy in alopecia areata – Part 2: Therapy, psychosocial and cosmetic support

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary This second part of the S3 guideline on the diagnosis and treatment of alopecia areata (AA), presents key recommendations on topical and systemic therapy, quality of life and support services. The first part of the guideline, published separately, covers the definition and content of epidemiology and diagnosis as well as comorbidities, risk and
Ulrike Blume‐Peytavi, Andria Constantinou, Tsenka Tomova‐Simitchieva, Adrian Tanew, Michael Sticherling, Hermann Girschick, Annika Vogt, Uwe Schwichtenberg, Uwe Gieler, André Märtens, Kerstin Zienert, Claudia Stenders, Ricardo Niklas Werner, Doris Wilborn   +13 more
wiley   +1 more source

Cyclophosphamide is associated with long‐term treatment‐free remission in patients with pemphigus

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objective Pemphigus treatment has seen significant advancements, yet long‐term remission remains a challenge. Comparative data on the long‐term effectiveness of available therapies are limited. We compared 10‐year relapse rates in pemphigus patients treated with azathioprine or cyclophosphamide plus high‐dose IV corticosteroids ...
Bettina Santler, Simon Lüdtke, Lena Dietze, Marie Schiffmann, Dominik Straube, Jan Ehrchen   +5 more
wiley   +1 more source

S1 Guideline: Therapy of generalized pustular psoriasis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The S1 guideline “Therapy of generalized pustular psoriasis (GPP)” is a German guideline developed in accordance with the criteria of the AWMF. The full version addresses clinical presentation, pathogenesis, diagnosis and differential diagnosis, comorbidities, and therapy.
Rotraut Mößner, Neda Cramer, Sascha Gerdes, Ulrike Hüffmeier, Andreas Körber, Kai Krause, Christian Kromer, Katharina Antonia Langen, Sandra Philipp, Knut Schäkel, Michael P. Schön, Michael Schultheis, Lukas Sollfrank, Petra Staubach, Michael Sticherling, Johannes Wohlrab, Dagmar Wilsmann‐Theis, Cornelia Paul   +17 more
wiley   +1 more source