Results 261 to 270 of about 48,551 (323)
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Obstetric Anesthesia Digest, 1981
We studied the first-trimester exposure to Bendectin for several major categories of birth defects among infants ascertained through the Metropolitan Atlanta Congenital Defects Program from 1968 to 1978. No associations were found between any of these defect categories and Bendectin exposure.
J F, Cordero +3 more
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We studied the first-trimester exposure to Bendectin for several major categories of birth defects among infants ascertained through the Metropolitan Atlanta Congenital Defects Program from 1968 to 1978. No associations were found between any of these defect categories and Bendectin exposure.
J F, Cordero +3 more
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Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice
Birth Defects Research, 2018The anticonvulsant valproic acid (VPA) has a known teratogenic effect capable of inducing major congenital malformations and developmental disorders. A comparative teratogenicity study of VPA and its analog valnoctamide (VCD), which is a new generation ...
Y. Lin +4 more
semanticscholar +1 more source
Teratology, 1982
AbstractPregnant rats and mice received high doses of cocaine hydrochloride by intraperitoneal injection. Despite treatment periods which included most of organogenesis, no increase in congenital abnormalities was observed. Rats showed significant reductions in maternal and fetal weights as well as increased resorption frequencies. Fetal edema was also
A G, Fantel, B J, Macphail
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AbstractPregnant rats and mice received high doses of cocaine hydrochloride by intraperitoneal injection. Despite treatment periods which included most of organogenesis, no increase in congenital abnormalities was observed. Rats showed significant reductions in maternal and fetal weights as well as increased resorption frequencies. Fetal edema was also
A G, Fantel, B J, Macphail
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New England Journal of Medicine, 1986
In 1981, Katie Laurel Wells was born with a cleft lip, an optic-nerve defect, and limb abnormalities, including absence of the left arm.
J L, Mills, D, Alexander
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In 1981, Katie Laurel Wells was born with a cleft lip, an optic-nerve defect, and limb abnormalities, including absence of the left arm.
J L, Mills, D, Alexander
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Annual Review of Nutrition, 1995
Vitamin A is a necessary nutrient in the diet. However, excessive doses of retinoids by pregnant women result in teratogenesis. In this chapter, we initially discuss the occurrence and characteristics of fetal malformations associated with maternal ingestion of natural and synthetic retinoids in both experimental animals and humans.
D R, Soprano, K J, Soprano
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Vitamin A is a necessary nutrient in the diet. However, excessive doses of retinoids by pregnant women result in teratogenesis. In this chapter, we initially discuss the occurrence and characteristics of fetal malformations associated with maternal ingestion of natural and synthetic retinoids in both experimental animals and humans.
D R, Soprano, K J, Soprano
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Journal of Animal Science, 1984
Many compounds synthesized by plants are known to be teratogenic in laboratory animals, but only a few have been shown by feeding trials to produce terata in livestock. Studies of plant teratogens affecting livestock have not moved forward in a systematic nor rapid way because of the logistical problems connected with such experiments in large animals.
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Many compounds synthesized by plants are known to be teratogenic in laboratory animals, but only a few have been shown by feeding trials to produce terata in livestock. Studies of plant teratogens affecting livestock have not moved forward in a systematic nor rapid way because of the logistical problems connected with such experiments in large animals.
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Annals of Internal Medicine, 1979
Excerpt To the editor: The excellent and valuable review in the June issue by Drs. Spark and Dickstein, "Bromocriptine and Endocrine Disorders" (1), referred to the potential teratogenicity of this...
R L, Elton, H M, Langrall
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Excerpt To the editor: The excellent and valuable review in the June issue by Drs. Spark and Dickstein, "Bromocriptine and Endocrine Disorders" (1), referred to the potential teratogenicity of this...
R L, Elton, H M, Langrall
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Clinics in Perinatology, 2014
In utero exposure to certain drugs early in pregnancy may adversely affect nephrogenesis. Exposure to drugs later in pregnancy may affect the renin-angiotensin system, which could have an impact on fetal or neonatal renal function. Reduction in nephron number and renal function could have adverse consequences for the child several years later. Data are
Thomas M, Morgan +2 more
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In utero exposure to certain drugs early in pregnancy may adversely affect nephrogenesis. Exposure to drugs later in pregnancy may affect the renin-angiotensin system, which could have an impact on fetal or neonatal renal function. Reduction in nephron number and renal function could have adverse consequences for the child several years later. Data are
Thomas M, Morgan +2 more
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American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 2011
AbstractA consideration of teratogenic exposures includes not only an agent (chemical, radiation, biologic) but an exposure level and timing of exposure. There are criteria by which exposures are evaluated for a causal connection with an abnormal outcome.
Sarah, Običan, Anthony R, Scialli
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AbstractA consideration of teratogenic exposures includes not only an agent (chemical, radiation, biologic) but an exposure level and timing of exposure. There are criteria by which exposures are evaluated for a causal connection with an abnormal outcome.
Sarah, Običan, Anthony R, Scialli
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Teratogen update: Iodine deficiency, a community teratogen
Teratology, 1997In the last decade, iodine deficiency disorders (IDD) have become recognized as the most common preventable cause of mental retardation worldwide. Iodine deficiency interferes severely with prenatal and postnatal growth and neurologic development of individuals.
J G, Hollowell, W H, Hannon
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