Results 91 to 100 of about 12,518 (290)

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

Termination of Pregnancy Following Periconception Isotretinoin Exposure in South Korea

Clinical and Experimental Obstetrics & Gynecology
Background: Despite South Korea’s Ministry of Food and Drug Safety (MFDS) risk management program (RMP) since June 2019, isotretinoin prescriptions have surged 2.5 times from 0.39 million in 2017 to 0.97 million in 2021.
Young-Rae Lee, Dong-Won Hwang, Kyoung-Chul Chun, Young-Ah Kim, Jae-Whoan Koh, Jung-Yeol Han, June-Seek Choi, Hye-Young Kwon   +7 more
doaj   +1 more source

Small head circumference at birth: an 8-year retrospective cohort study in China

BMJ Paediatrics Open, 2019
Objective Head circumference is considered a reliable assessment of the volume of the underlying brain. We sought to identify risk factors (maternal factors or antenatal antecedents) for microcephaly and to assess the effects of microcephaly on neonatal ...
Wen Sun, Nathalie Auger, Shiliang Liu, Yanmei Pan, Lijuan Dai, Sihui Li, Sushan Xie, Shi Wu Wen, Dunjin Chen   +8 more
doaj   +1 more source

Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models. [PDF]

, 2018
An excessive requirement for methionine (MET) for growth, termed MET dependence, appears to be a general metabolic defect in cancer. We have previously shown that cancer-cell growth can be selectively arrested by MET restriction such as with recombinant ...
Chemielwski, Bartosz, Dry, Sarah M, Eckardt, Mark A, Eilber, Fritz C, Han, Qinghong, Hoffman, Robert M, Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Li, Shukuan, Li, Yunfeng, Miyake, Kentaro, Miyake, Masuyo, Nelson, Scott D, Russell, Tara A, Singh, Arun S, Tan, Yuying, Unno, Michiaki   +17 more
core   +1 more source

Knee arthroplasty failure is associated with significant systemic multimetal exposure

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study investigated whether patients scheduled for revision total knee arthroplasty (TKA) are systemically exposed to arthroplasty metals, and whether systemic metal levels in these patients differ depending on the implants' levels of constraint.
Anna Flindt, Katrin Huesker, Georg Volk, Juliane Fuchs, André Hofer, Ulrich Schietsch, Georgi I. Wassilew, Janosch Schoon, Anastasia Rakow   +8 more
wiley   +1 more source

From abortion-inducing medications to Zika Virus Syndrome: 27 years experience of the First Teratogen Information Service in Latin America

Genetics and Molecular Biology, 2019
In 1990, the first Teratogen Information Service in Brazil (SIAT) was implemented in the Medical Genetics Service at Hospital de Clinicas de Porto Alegre.
Lavinia Schüler-Faccini, Maria Teresa Vieira Sanseverino, Alberto Mantovani Abeche, Fernanda Sales Luiz Vianna, Lucas Rosa Fraga, Anastacia Guimaraes Rocha, André Anjos da Silva, Paulo Ricardo Assis de Souza, Artur Hartmann Hilgert, Camila Pocharski Barbosa, Caroline Grasso Kauppinem, Daniela Fernandes Martins, Daniela Silva Santos, Gabriel Henrique Colpes, Gabriela Ecco, Helena Margot Flores Soares da Silva, Louise Piva Penteado, Tatiane dos Santos   +17 more
doaj   +1 more source

Methanol and isopropanol embryo dosage response curves for wild-type and ethanol-sensitive zebrafish [PDF]

, 2016
It is well established that ethanol has an array of negative effects on developing embryos, from craniofacial abnormalities to cognitive deficits and behavioral disorders.
Anderson, Ashley
core   +1 more source

Pengaruh Teratogen AlCl3 (Aluminium chloride) terhadap Perkembangan Embrio Ayam (Gallus gallus domesticus)

, 2023
Najib Rahman. G, Saskia Putri Azeli, Elvira Hayu, Yuni Ahda, Yusni Atifah   +4 more
openalex   +2 more sources

Valproic Acid-Induced Syringomyelia in Rat Fetuses

پزشکی بالینی ابن سینا, 2005
Among antiepileptic drugs, valproic acid (VA) is a well known    teratogenic agent. Although axial skeletal malformations (vertebral column) and limb defects have been described, its main target organ is neuroepithelium of neural tube. Therefore it seems
Mohammad Reza Nikravesh, Mahdi Jalali
doaj  

Congenital Single Digit Deformities: Series of Cases in Multiple Families in Remote Villages of Haryana

Journal of Surgical Specialties and Rural Practice
Background and Purpose: Congenital deformities occur due to abnormal development of limbs in the intrauterine life. The exact cause of this type of defect is not known but can be associated with environmental factors (drug history or exposure of chemical
Gunjan Upadhyay, Ashish Arya, Ved Prakash Anchal, Santosh Laxmanrao Munde, Ghanapriya Singh, Mitali Kapoor   +5 more
doaj   +1 more source