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Mutations in CCIN cause teratozoospermia and male infertility
Teratozoospermia is usually associated with defective spermiogenesis and is a disorder with considerable genetic heterogeneity. Although previous studies have identified several teratozoospermia-associated genes, the etiology remains unknown for a majority of affected men.
Yong, Fan +16 more
exaly +3 more sources
Genetic aspects of monomorphic teratozoospermia: a review [PDF]
Teratozoospermia is characterized by the presence of spermatozoa with abnormal morphology over 85 % in sperm. When all the spermatozoa display a unique abnormality, teratozoospermia is said to be monomorphic. Two forms of monomorphic teratozoospermia, representing less than 1 % of male infertility, are recognized: macrozoospermia (also called ...
Frédéric Morel
exaly +3 more sources
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Microsurgical fertilization and teratozoospermia
Human Reproduction, 1991Semen parameters were correlated with the outcome of partial zona dissection (PZD) in 42 couples with male factor infertility. Although fertilization rates were reduced, 12% of the embryos implanted following replacement. Spermatozoa from teratozoospermic sperm populations were able to fuse with oocytes following zona penetration through the artificial
Jacques Cohen +11 more
openaire +2 more sources
Aneuploid spermatozoa in infertile men: Teratozoospermia
Molecular Reproduction and Development, 2002AbstractWe and others have demonstrated that infertile men who are candidates for intracytoplasmic sperm injection (ICSI) have an increased frequency of chromosomal abnormalities in their sperm. Reports based on prenatal diagnosis of ICSI pregnancies have confirmed the increased frequency of chromosomal abnormalities in offspring.
Cristina, Templado +5 more
openaire +2 more sources
Isolated teratozoospermia and in vitro fertilization
Journal of Assisted Reproduction and Genetics, 1996To show whether increased amounts of spermatozoa used in insemination of preovulatory oocytes in isolated teratozoospermia according to Kruger's strict criteria gives good fertilization rates.This study was carried out from September 1993 to November 1994 for a total of 77 cycles, with sperm samples classified according to Kruger's strict ...
H, Figueiredo +4 more
openaire +2 more sources
Isolated teratozoospermia and intrauterine insemination
Fertility and Sterility, 2003This study tests the hypothesis that IUI treatment in cases with isolated teratozoospermia (
Carl, Spiessens +3 more
exaly +3 more sources
Asthenozoospermia/Teratozoospermia and Infertility
Archives of Andrology, 1990Abnormal spermiograms with asthenozoospermia and teratozoospermia are often classified as subfertile, and the cause of these findings has been obscure. A new method, the 8-h in vitro motility profile test (MPT), showed a significant difference in motility profile between 130 fertile men and men of infertile couples.
openaire +2 more sources
Teratozoospermia and its effect on male fertility potential
Andrologia, 1999Teratozoospermia and its significance for male fertility problems is discussed. Different points of view and available information concerning the phenomenon of teratozoospermia have been presented. Ongoing debate about the influence of sperm morphology on male infertility and IVF results emphasizes the fact that when sperm morphology is evaluated using
M, Szczygiel, M, Kurpisz
exaly +3 more sources
Teratozoospermia: spotlight on the main genetic actors in the human [PDF]
Male infertility affects >20 million men worldwide and represents a major health concern. Although multifactorial, male infertility has a strong genetic basis which has so far not been extensively studied. Recent studies of consanguineous families and of small cohorts of phenotypically homogeneous patients have however allowed the identification of a ...
Charles Coutton +2 more
exaly +4 more sources
[DAZL gene polymorphisms and astheno-teratozoospermia].
Zhonghua nan ke xue = National journal of andrology, 2013To investigate the association between single nucleotide polymorphism (SNP) of the DZAL gene in infertile Han Chinese males with astheno-teratozoospermia.We collected semen samples from 173 infertile Han Chinese men with astheno-teratozoospermia (case group) and 175 age-matched normal male volunteers (control group) for semen routine and morphological ...
Lu-Wei, Ye +6 more
openaire +2 more sources

