Results 51 to 60 of about 15,140 (255)
Mycoses (Berlin), 2018 In the last few years, infections caused by dermatophytes along with a concomitant increase in the number of difficult to treat cases have increasingly been recognised, indicating that dermatophytosis remains a challenging public health problem.
Ashutosh Kumar Singh +7 more
semanticscholar +1 more source
Treatment of cutaneous sporotrichosis with terbinafine
British Journal of Dermatology, 1992 Terbinafine, an allylamine antifungal agent, has been shown to have excellent in-vitro activity against dermatophytes. Several other fungi of importance also show in-vitro sensitivity. Because terbinafine is fungicidal rather than fungistatic in action, its efficacy in treating such fungal infections requires evaluation.
Peter R. Hull, H.F. Vismer
openaire +3 more sources
Cytoplasmic fungal lipases release fungicides from ultra-deformable vesicular drug carriers. [PDF]
PLoS ONE, 2012 The Transfersome® is a lipid vesicle that contains membrane softeners, such as Tween 80, to make it ultra-deformable. This feature makes the Transfersome® an efficient carrier for delivery of therapeutic drugs across the skin barrier.
Gero Steinberg
doaj +1 more source
Journal of Fungi, 2023 Trichophyton indotineae causes resistant dermatophytosis to terbinafine. The global spread of terbinafine-resistant Trichophyton indotineae strains with mutations in the squalene epoxidase gene is a major issue.
Giuseppe Russo +3 more
doaj +1 more source
Small Science, EarlyView.This study presents a novel method for rapidly evaluating dermal drug delivery systems (DDSs). Using mass spectrometry imaging and automated data analysis, it visualizes drug distribution within skin layers in under 10 min. Tested with three nanoscale DDSs for antifungal terbinafine, the approach reveals key differences in drug permeation depth and ...
Ravit Yakobi Arancibia +9 more
wiley +1 more source
Antimicrobial Agents and Chemotherapy, 2019 In recent years, cases involving terbinafine-resistant Trichophyton isolates have been reported increasingly, particularly in India. We present 14 cases of terbinafine treatment failure in Trichophyton-infected Danish patients due to acquired resistance.
D. Saunte +9 more
semanticscholar +1 more source
Infection, 2020 Dermatomycoses are the most common fungal infections in the world affecting a significant part of the human and animal population. The majority of zoophilic infections in humans are caused by Trichophyton mentagrophytes.
Dominik Łagowski +4 more
semanticscholar +1 more source
Climate Change, Natural Disasters, and Cutaneous Fungal Infections
International Journal of Dermatology, EarlyView.ABSTRACT Fungal infections are an important source of morbidity and mortality that can manifest as superficial or invasive diseases. Diagnostic techniques for human fungal pathogens remain problematic, and multi‐drug resistance is emerging. This review addresses the potential emergence of new fungal pathogens in changing environments and reported ...
Aditya K. Gupta +2 more
wiley +1 more source
Presumed Trichophyton indotineae Infection in Children: A Call for Heightened Clinical Awareness
Pediatric Dermatology, EarlyView.ABSTRACT Trichophyton indotineae is a fungus that is often antifungal‐resistant and presents with exuberant infection. It has been increasingly reported across the world, posing significant diagnostic challenges. We describe a case of a toddler with a history of travel to Bangladesh, presenting with persistent annular scaling plaques of dermatophytosis
Sriram Palepu, James R. Treat
wiley +1 more source
Scientific Reports, 2020 Dermatophytosis has gained interest in India due to rise in terbinafine resistance and difficulty in management of recalcitrant disease. The terbinafine resistance in dermatophytes is attributed to single nucleotide polymorphisms (SNPs) in squalene ...
S. Shankarnarayan +8 more
semanticscholar +1 more source