Results 61 to 70 of about 10,738 (299)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Terbium doped glasses: their optical properties and potential applications [PDF]
The optical properties of inorganic glasses doped with terbium have been investigated with particular emphasis on silicate glass systems. The effect of increasing terbium concentration on the refractive index of silicate glasses has been investigated and
Hoaksey, A.
core +1 more source
Synthesis and structure of hydrated terbium carbonate [PDF]
992-994Crystalline terbium carbonate has been synthesized using ammonium bicarbonate as a precipitant. The X-ray diffraction data have been indexed and these indicate a monoclinic system with cell parameters, a= 18.745Å, b= 14.244Å, c= 15.329Å and β = 95.
Song, Liu, Rongjun, Ma
core
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Efficient Electroluminescence from a New Terbium Complex
Although lanthanide complexes have distinct advantages for use as light-emitting materials, such as sharp emission bands and 100% quantum efficiency theoretically, their performance was far below what is expected.
Mei Shi (133738) +4 more
core +2 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Rare earth elements (REEs) are essential for high-tech and low-carbon economies. Achieving global net-zero emissions by 2050 would require a significant increase in mineral input, including 3–7 times more REEs.
Brajendra Mishra (16944206) +3 more
core +2 more sources
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The results of synthesis and analysis of the film structures fabricated from suspensions based on titanium dioxide sol and terbium-doped yttrium aluminum composite powder are presented.
L. S. Khoroshko +6 more
doaj
A quaternion-based attitude unscented Kalman filter is formulated with quaternion errors parameterized by small angle approximations and is applied to a filter with a state vector consisting of the attitude quaternion and the gyro bias vector. The filter
Murty S. Challa +2 more
doaj +1 more source

