Results 91 to 100 of about 4,105 (201)
Journal of Pharmacological Sciences, 2007 This study investigated endogenous mediators involved in mosquito allergy-associated itching in mice. An intradermal injection of an extract of mosquito salivary gland elicited marked scratching in sensitized mice.
Yasushi Kuraishi +6 more
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Enthalpy of solution of terfenadine in ethanol/water mixtures
, 2020 The enthalpy of solution of terfenadine in ethanol/water mixtures, 0±20.5 wt.% of water was determined by calorimetry. A Sudden increase of 1±2 kJ mol À1 in the enthalpy at a concentration value around 0.01 mol kg À1 is observed.
Adriano T Sousa +6 more
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, 1993 Calcium channel affinity of terfenadine and its optical isomers was determined by the displacement of [3H]nitrendipine on rat cerebral cortex membranes. Terfenadine showed a pKd of 6·36±0·03 whereas its R(+)-isomer (VUF4567) had a pKd value of 6·39±0·03 ...
P Caldirola, M Q Zhang, H Timmerman
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, 2014 Background: The aim of this work was to evaluate the analytical performance of a fully automated droplet-based surface-sampling system for determining the distribution of the drugs acetaminophen and terfenadine, and their metabolites, in rat thin tissue ...
Kertesz, Vilmos +5 more
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Characterization of terfenadine as a model of a hydrophobic amorphous form of a drug and preparation and characterization of some of its derivatives [PDF]
, 2003 Terfenadine was used as a model hydrophobic drug from which an amorphous form was prepared by melting followed by slow or quench-cooling. It was not possible to crystallize amorphous terfenadine at elevated RH either in the isothermal microcalorimeter or
Samra, Raya M.
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Examined the effects of chronic treatment with non-sedative histamine H-sub-1 receptor antagonist terfenadine on the behavioral and immunological parameters in the olfactory bulbectomized (OB) rat model of depression. OB Sprague-Dawley rats were injected
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, 2000 Exposure of cultured neurons to nanomolar concentrations of terfenadine prevented the NMDA receptor-mediated early appearance (30min.) of toxicity signs induced by the voltage sensitive sodium channel activator veratridine.
A. Novelli +4 more
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Cardiovascular effects of terfenadine, cetirisine and laratodine [PDF]
, 1997 Design. - Non-sedative antihistanimic drugs, terfenadine, cetinizine, loratadine and acrivastine were given to four groups of patients each consisted of 10 patients for 10 days.
Alkan, M. +4 more
core
, 2007 23 p.Cytochrome P450 enzymes are heme-containing oxidoreductases involved in the metabolism of both endogenous and exogenous compounds in the human body. One class of exogenous compounds known to be metabolized by P450s is pharmaceutical agents.
Meyers, Jacob I.
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CNS Side-effect of Fexofenadine, 180 mg Tablet
Siriraj Medical Journal, 1999 Fexofenadine, the derivative of terfenadine, has been shown to produce no side-effect on the heart, not distributed to the central nervous system (CNS), and having high selectivity for peripheral histamine H1-receptors.
B Dhorranintra, S Klyprayong
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