Results 71 to 80 of about 4,105 (201)
Repurposing the Antihistamine Terfenadine for Antimicrobial Activity against Staphylococcus aureus
, 2015 Staphylococcus aureus is a rapidly growing health threat in the U.S., with resistance to several commonly prescribed treatments. A high-throughput screen identified the antihistamine terfenadine to possess, previously unreported, antimicrobial activity ...
Jessamyn I. Perlmutter (1340724) +7 more
core +1 more source
, 1992 The effect of terfenadine on the plasma concentrations of substance P and vasoactive intestinal polypeptide (VIP) was studied in 7 healthy subjects and 8 subjects with the common cold.
Shunji Asakura +3 more
core +1 more source
Acta Dermato-Venereologica, 2017 A recent study suggests that interleukin-31 (IL-31) exerts its effect via indirect mechanisms rather than through direct stimulation of cutaneous nerves.
Tsugunobu Andoh +2 more
doaj +1 more source
Fexofenadine Brain Exposure and the Influence of Blood-Brain Barrier P-Glycoprotein After Fexofenadine and Terfenadine Administration [PDF]
, 2009 P-glycoprotein (P-gp) plays an important role in determining net brain uptake of fexofenadine. Initial in vivo experiments with 24-h subcutaneous osmotic minipump administration demonstrated that fexofenadine brain penetration was 48-fold higher in mdr1a(
Bridges, A. S. +4 more
core +1 more source
Arritmia ventricular maligna tras empleo simultáneo de terfenadina y ketoconazol
Revista Cubana de Medicina, 1998 Se reportó el caso de una paciente joven que presentó arritmia ventricular maligna tras empleo simultáneo de terfenadina y ketoconazol, con el objetivo de ratificar lo contraproducente de determinadas asociaciones farmacológicas. El cuadro clínico estuvo
Luis Senra Armas +4 more
doaj
Journal of Analytical Methods in Chemistry, 2019 A comparative study of chemical stability of terfenadine (TER) and its in vivo metabolite fexofenadine (FEX) was performed. Both TER and FEX were subjected to high temperature at different pH and UV/VIS light at different pH and then quantitatively ...
Anna Gumieniczek +5 more
doaj +1 more source
Cellular Physiology and Biochemistry, 2013 Background/Aims: Safety pharmacology requires novel model systems for the detection of cardiac side effects. Ranging from cell-based systems to model organisms, no model available to date reflects the complexity of the human heart and evokes the great ...
Julia M. Mehnert +2 more
doaj +1 more source
Efek Terfenadine terhadap Aktifitas Caspase-9 pada Kultur Sel Melanoma Maligna
, 2011 Tujuan: Mengetahui pengaruh pemberian terfenadine terhadap aktifitas caspase-9 pada Kultur melanoma maligna cell line CRL 1872 dan hubungan antara perubahan dosis terfenadin dengan perubahan aktivitas caspase-9.
Sjafrida
core
Study of Polymorphism From DSC Melting Curves; Polymorphs of Terfenadine [PDF]
, 2002 Terfenadine samples prepared by crystallization in different media and supersaturation conditions were used to investigate the polymorphism of the substance. The study was based on DSC melting curves.
Redinha, J. +12 more
core +1 more source
Antihistamines for the treatment of urticaria in Mexico
Revista Alergia México, 2015 There are four types of histamine receptors. Allergic symptoms, especially those in rhinoconjunctivitis and urticaria, are mainly caused by activation of histamine receptor 1 (H1).
Désirée Larenas-Linnemann +14 more
doaj +1 more source