Results 1 to 10 of about 6,724 (199)

Terlipressin‐induced skin necrosis in cirrhotic patients—A case report and comprehensive literature review [PDF]

Clinical Case Reports
Key Clinical Message The occurrence of terlipressin‐induced skin necrosis in cirrhotic patients is a rare but serious adverse event that warrants further investigation.
Ashraf I. Ahmed, Muhammad Zain Kaleem, Shahem Abbarh, Haider Hussein Barjas, Abdellatif Ismail, Mhd Kutaiba Albuni, Bisher Sawaf   +6 more
doaj   +3 more sources

Defining Renal Recovery in Patients With Hepatorenal Syndrome-Acute Kidney Injury: Experience From North American Studies. [PDF]

JGH Open
ABSTRACT Introduction The degree of improvement in serum creatinine (SCr) has previously been suggested as a sensitive indicator of treatment response in patients with hepatorenal syndrome‐acute kidney injury (HRS‐AKI), while HRS reversal remains the primary endpoint in clinical trials.
Mujtaba MA, Elsiesy H, Faiz S, Hussain SA, Gamilla-Crudo AKN, Karim A, Khan MI, Khattak MW, Zafar Z, Kueht M, Jamil K.   +10 more
europepmc   +2 more sources

Terlipressin versus placebo or noradrenalin in the treatment of hepatorenal syndrome: a systematic review and meta-analysis [PDF]

Frontiers in Pharmacology
BackgroundHepatorenal syndrome (HRS) bears a very poor prognosis with unmet need for safe and effective therapies. This systematic review and meta-analysis aimed to re-assess safety and efficacy of terlipressin versus placebo or noradrenaline for HRS ...
Yue-Meng Wan, Song-Quan Huang, Hua-Mei Wu, Yu-Hua Li, Hong-Jing Yin, Ying Xu   +5 more
doaj   +2 more sources

Continuous terlipressin versus vasopressin infusion in septic shock (TERLIVAP): a randomized, controlled pilot study [PDF]

, 2009
Introduction Recent clinical data suggest that early administration of vasopressin analogues may be advantageous compared to a last resort therapy. However, it is still unknown whether vasopressin and terlipressin are equally effective for hemodynamic ...
Andrea Morelli, Christian Ertmer, Sebastian Rehberg, Matthias Lange, Alessandra Orecchioni, Valeria Cecchini, A. Bachetoni, Mariadomenica D’Alessandro, Hugo Van Aken, P Pietropaoli, Martin Westphal   +10 more
openalex   +5 more sources

Hypotension after anesthesia induction in patients taking tricyclic antidepressants-A case series. [PDF]

Acta Anaesthesiol Scand
Abstract Background Hypotension is commonly observed after induction of anesthesia. Risk factors for intraoperative hypotension include higher ASA class, older age, propofol use, combined general/regional anesthesia, emergency surgery, and use of antihypertensives.
Lodsgaard M, Melchiors BB, Krøigaard M, Garvey LH.   +3 more
europepmc   +2 more sources

FDA-approved drugs featuring macrocycles or medium-sized rings. [PDF]

Arch Pharm (Weinheim)
This review presents 17 macrocyclic drugs approved by the U.S. Food and Drug Administration during the past 5 years, highlighting their importance and critical role in modern therapeutics, and the innovative synthetic approaches for the construction of these macrocycles.
Du Y, Semghouli A, Wang Q, Mei H, Kiss L, Baecker D, Soloshonok VA, Han J.   +7 more
europepmc   +2 more sources

Terlipressin for the Prevention and Treatment of Renal Decline in Hepatorenal Syndrome: A Drug Profile [PDF]

Gastroenterology Insights, 2023
Hepatorenal syndrome stands as one of several potential triggers of acute kidney injury in individuals grappling with either acute or persistent liver ailments. The nature of the decline in kidney function has led to the identification of two variants of
Ahlam Ayyad, Rami A. Al-Horani
doaj   +2 more sources

Severe Bradycardia Associated with the Use of Terlipressin: A Case Report [PDF]

Case Reports in Gastroenterology
Introduction: Although terlipressin is known to cause bradycardia, this adverse effect is usually described in association with hypertension and is considered a benign compensatory response mediated by arterial baroreceptors.
Alex Yartsev, Jessica T. Nguyen
doaj   +2 more sources

Terlipressin combined with conservative fluid management attenuates hemorrhagic shock-induced acute kidney injury in rats [PDF]

Scientific Reports, 2022
Hemorrhagic shock (HS), a major cause of trauma-related mortality, is mainly treated by crystalloid fluid administration, typically with lactated Ringer’s (LR).
Leticia Urbano Cardoso Castro, Denise Aya Otsuki, Talita Rojas Sanches, Felipe Lima Souza, Mirela Aparecida Rodrigues Santinho, Cleonice da Silva, Irene de Lourdes Noronha, Amaro Nunes Duarte-Neto, Samirah Abreu Gomes, Luiz-Marcelo Sá Malbouisson, Lucia Andrade   +10 more
doaj   +2 more sources

Continuous recurrence of type 1 hepatorenal syndrome and long-term treatment with terlipressin and albumin: A new exception to MELD score in the allocation system to liver transplantation? [PDF]

, 2011
Background & Aims The recurrence of type 1 hepatorenal syndrome has been described in up to 20% of responders to terlipressin and albumin after the discontinuation of the treatment.
Salvatore Piano, Filippo Morando, Silvano Fasolato, M. Cavallin, Noéli Boscato, Patrizia Boccagni, Giacomo Zanus, Umberto Cillo, Angelo Gatta, Paolo Angeli   +9 more
openalex   +4 more sources