Practice guidance for the use of terlipressin for liver cirrhosis–related complications [PDF]
Therapeutic Advances in Gastroenterology, 2022 Background: Liver cirrhosis is a major global health burden worldwide due to its high risk of morbidity and mortality. Role of terlipressin for the management of liver cirrhosis–related complications has been recognized during recent years.
Xingshun Qi +40 more
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Annals of Hepatology, 2009 Introduction. Type 1 hepatorenal syndrome (HRS) is a functional renal failure that complicates end-stage cirrhosis. The vasopressin analogue terlipressin has been associated with improved renal function in patients with type 1 HRS.Aim.
Linda E. Muñoz +7 more
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Mapping the hemodynamic effects of terlipressin in patients with hepatorenal syndrome using advanced magnetic resonance imaging [PDF]
JHEP ReportsBackground & aims: Terlipressin improves renal function in ∼40% of patients with hepatorenal syndrome–acute kidney injury (HRS-AKI). Nonetheless, the pathophysiological mechanisms of terlipressin remain unclear.
Karen Vagner Danielsen +10 more
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The use of terlipressin to treat refractory hypotension during allograft kidney transplantation: a report of 4 cases and literature review [PDF]
BMC AnesthesiologyBackground Intraoperative hypotension is a recognized risk factor for delayed graft function (DGF) after kidney transplantation and may compromise both short- and long-term allograft outcomes.
Wen-He Yang +6 more
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Hyponatraemia Induced by Terlipressin in Patients Diagnosed with Decompensated Liver Cirrhosis and Acute Variceal Bleeding [PDF]
MedicinesBackground: Hyponatraemia is a rare but potentially life-threatening complication of terlipressin therapy. Case history: In the current case, a 39-year-old female with decompensated liver cirrhosis (Child-Pugh C) and acute variceal bleeding experienced a
Mahmoud Elshehawy +4 more
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Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome [PDF]
New England Journal of Medicine, 2021 Florence S H Wong +2 more
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Adjunctive terlipressin versus placebo in the treatment of refractory septic shock: a randomized, placebo-controlled trial. [PDF]
Crit CareTongyoo S +3 more
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Effectiveness and safety evaluation of terlipressin in the treatment of intestinal paralysis in end-stage liver disease [PDF]
BMC GastroenterologyBackground and aims Intestinal paralysis is a common complication in end-stage liver disease (ESLD), our aim is to assess the effectiveness and safety of low-dose terlipressin for treating intestinal paralysis in ESLD.
Xia Wan +7 more
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Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome
AAPS Open, 2022 The objective of this population pharmacokinetics (PK) analysis was to characterize the PK of terlipressin and its active metabolite, lysine-vasopressin (L-VP), in patients with hepatorenal syndrome (HRS), following intravenous administration of ...
Xiaofeng Wang, Khurram Jamil
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