Terlipressin for sinusoidal obstruction syndrome-associated acute kidney injury: a novel application [PDF]
Clin Kidney JSinusoidal obstruction syndrome (SOS) is a life-threatening complication of hematopoietic cell transplantation that can lead to multiorgan failure, including acute kidney injury (AKI) due to hepatorenal syndrome (HRS)-like physiology.
Callie J Meath +4 more
semanticscholar +2 more sources
Clinical Case ReportsKey Clinical Message The occurrence of terlipressin‐induced skin necrosis in cirrhotic patients is a rare but serious adverse event that warrants further investigation.
Ashraf I. Ahmed +6 more
doaj +2 more sources
Mapping the hemodynamic effects of terlipressin in patients with hepatorenal syndrome using advanced magnetic resonance imaging [PDF]
JHEP ReportsBackground & aims: Terlipressin improves renal function in ∼40% of patients with hepatorenal syndrome–acute kidney injury (HRS-AKI). Nonetheless, the pathophysiological mechanisms of terlipressin remain unclear.
Karen Vagner Danielsen +10 more
doaj +2 more sources
The relationship between mean arterial pressure and terlipressin in hepatorenal syndrome-acute kidney injury reversal: A post hoc analysis [PDF]
HepatologyBackground and Aims: Terlipressin reverses hepatorenal syndrome-acute kidney injury (HRS-AKI) by increasing mean arterial pressure (MAP). To further characterize the relationship between terlipressin and MAP and their impact on HRS-AKI reversal, we used ...
Giuseppe Cullaro +4 more
semanticscholar +2 more sources
A retrospective analysis of hyponatremia during terlipressin treatment in patients with esophageal or gastric variceal bleeding due to portal hypertension [PDF]
JGH Open, 2020 Background and Aim To explore the risk factors of hyponatremia caused by terlipressin. Methods Forty‐four patients with acute variceal bleeding treated with terlipressin from December 2016 to December 2018 were analyzed.
Xv Han +4 more
doaj +2 more sources
Efficacy and Safety of Terlipressin Infusion in Hepatorenal Syndrome-Acute Kidney Injury (HRS-AKI): A Retrospective Observational Study [PDF]
CureusBackground Hepatorenal syndrome-acute kidney injury (HRS-AKI) is an event that occurs in chronic liver disease (CLD) and is associated with high morbidity and mortality. Terlipressin, a vasopressin analog, is used for the treatment of portal hypertension-
Manoj Gowda +6 more
openalex +2 more sources
Severe Bradycardia Associated with the Use of Terlipressin: A Case Report
Case Reports in GastroenterologyIntroduction: Although terlipressin is known to cause bradycardia, this adverse effect is usually described in association with hypertension and is considered a benign compensatory response mediated by arterial baroreceptors.
Alex Yartsev, Jessica T. Nguyen
doaj +2 more sources
Critical Care Explorations, 2023 IMPORTANCE AND OBJECTIVES:. This study assessed the potential advantages of treating hepatorenal syndrome-acute kidney injury (HRS-AKI) with terlipressin versus placebo in the ICU setting. DESIGN:.
Constantine J. Karvellas, MD +3 more
doaj +2 more sources
Safety and efficacy of continuous terlipressin infusion in HRS-AKI in a transplant population
Liver transplantationHepatorenal syndrome-acute kidney injury (HRS-AKI) is associated with significant morbidity and mortality. While liver transplantation is the definitive treatment, continuous terlipressin infusion for HRS-AKI may provide benefit and, as such, was ...
K. Rajender Reddy +19 more
openalex +2 more sources
Frontiers in PharmacologyBackgroundHepatorenal syndrome (HRS) bears a very poor prognosis with unmet need for safe and effective therapies. This systematic review and meta-analysis aimed to re-assess safety and efficacy of terlipressin versus placebo or noradrenaline for HRS ...
Yue-Meng Wan +5 more
doaj +2 more sources