Results 41 to 50 of about 7,672 (251)

Antiparallel β‐Sheet as a Key Motif of Amyloid‐β Inhibitor Designed via Topological Peptide Reprogramming

open access: yesAngewandte Chemie, Volume 137, Issue 28, July 7, 2025.
Targeting Amyloid‐β (Aβ) aggregation requires a peptide‐based approach that accounts for the structural heterogeneity of Aβ. Here, we employ topological reprogramming via disulfide bonds to stabilize antiparallel β‐sheets within the dimeric peptide.
Dongjoon Im   +5 more
wiley   +2 more sources

Terlipressin in combination with albumin as a therapy for hepatorenal syndrome in patients aged 65 years or older

open access: yesAnnals of Hepatology, 2023
Introduction and Objectives: Clinical data for older patients with advanced liver disease are limited. This post hoc analysis evaluated the efficacy and safety of terlipressin in patients aged ≥65 years with hepatorenal syndrome using data from 3 Phase ...
Muhammad A. Mujtaba   +8 more
doaj  

Vasopressin and Terlipressin in the Treatment of Vasodilatory Septic Shock: A Systematic Review

open access: yesProceedings of Singapore Healthcare, 2011
Background: Vasodilatory septic shock unresponsive to fluid resuscitation requires the addition of vasopressors. Catecholamines remain the first line vasopressor therapy, but treatment failure is a potential problem.
Jie Lin Soong BSc (Pharm) (Hons)   +1 more
doaj   +1 more source

Role of Terlipressin in Patients With Hepatorenal Syndrome-Acute Kidney Injury Admitted to the ICU: A Substudy of the CONFIRM Trial

open access: yesCritical Care Explorations, 2023
IMPORTANCE AND OBJECTIVES:. This study assessed the potential advantages of treating hepatorenal syndrome-acute kidney injury (HRS-AKI) with terlipressin versus placebo in the ICU setting. DESIGN:.
Constantine J. Karvellas, MD   +3 more
doaj   +1 more source

Terlipressin-Associated Complete Heart Block. [PDF]

open access: yesACG Case Rep J
ABSTRACT Terlipressin has been recently approved in the United States to treat hepatorenal syndrome, a feared complication of both acute and chronic liver diseases. Side effects of the medication have been studied through clinical trials and the precedent use in Europe, as well as extrapolation from its analog vasopressin.
Song J, Alfie T, Heist EK, Chung RT.
europepmc   +3 more sources

The Royal Free Hospital score: a calibrated prognostic model for patients with cirrhosis admitted to intensive care unit. Comparison with current models and CLIF-SOFA score [PDF]

open access: yes, 2014
Prognosis for patients with cirrhosis admitted to intensive care unit (ICU) is poor. ICU prognostic models are more accurate than liver-specific models.
Agarwal, B   +6 more
core   +1 more source

Iatrogenic bleeding during flexible bronchoscopy: risk factors, prophylactic measures and management. [PDF]

open access: yes, 2017
Significant iatrogenic bleeding during flexible bronchoscopy is fortunately rare and usually self-limiting. Life-threatening bleeding, however, can occur, especially after conventional or cryoprobe-assisted transbronchial biopsy.
Breuer   +27 more
core   +3 more sources

Terlipressin combined with conservative fluid management attenuates hemorrhagic shock-induced acute kidney injury in rats

open access: yesScientific Reports, 2022
Hemorrhagic shock (HS), a major cause of trauma-related mortality, is mainly treated by crystalloid fluid administration, typically with lactated Ringer’s (LR).
Leticia Urbano Cardoso Castro   +10 more
doaj   +1 more source

Current trends in vasopressor use to the operating room : a pharmacoepidemiologic study in French teaching and military hospitals [PDF]

open access: yes, 2017
Objectives: Phenylephrine, ephedrine and norepinephrine are the vasopressors most commonly used in the operating room to treat anaesthesia-induced hypotension.
Armoiry, Xavier   +4 more
core   +2 more sources

Vasopressin and terlipressin in adult vasodilatory shock [PDF]

open access: yesCritical Care, 2012
We have read with interest the study by Serpa Neto and colleagues showing that vasopressin use in vasodilatory shock is associated with reduced mortality [1]. However, we believe there are three aspects that need clarification. In relation to the paper recently published by our group on the same topic, the authors correctly state that 'we only ...
Polito, Angelo   +4 more
openaire   +3 more sources

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