Introduction. Type 1 hepatorenal syndrome (HRS) is a functional renal failure that complicates end-stage cirrhosis. The vasopressin analogue terlipressin has been associated with improved renal function in patients with type 1 HRS.Aim.
Linda E. Muñoz +7 more
doaj +1 more source
Vasopressin and Terlipressin in the Treatment of Vasodilatory Septic Shock: A Systematic Review
Background: Vasodilatory septic shock unresponsive to fluid resuscitation requires the addition of vasopressors. Catecholamines remain the first line vasopressor therapy, but treatment failure is a potential problem.
Jie Lin Soong BSc (Pharm) (Hons) +1 more
doaj +1 more source
Terlipressin-induced hyponatremic encephalopathy in a noncirrhotic patient
Terlipressin, an analogue of vasopressin, is frequently used for the management of esophageal varices bleeding and hepatorenal syndrome. Terlipressin therapy in portal hypertensive patients is frequently associated with hyponatremia, but is rarely ...
Yao-Kuang Wang +5 more
doaj +1 more source
Background: Hepatorenal syndrome-acute kidney injury (HRS-AKI) carries significant morbidity and mortality among those with end-stage liver disease. Bolus terlipressin for treatment of HRS-AKI received FDA approval in September 2022. US implementation of
Ethan Weinberg +14 more
doaj +1 more source
Hemodynamic profile of terlipressin and octreotide in patients with cirrhosis and portal hypertension: a randomized, single-blind clinical trial. [PDF]
Perez-Campuzano V +15 more
europepmc +2 more sources
Initial serum sodium concentration determines the decrease in sodium level after terlipressin administration in patients with liver cirrhosis [PDF]
BACKGROUND: Terlipressin, as a prodrug of vasopressin, has agonistic effects on the V1 receptor and partial agonistic effects on renal vasopressin V2 receptors. However, its effects on serum sodium concentration are controversial.
Dae-Hong Jeon +7 more
core +1 more source
Background. Terlipressin is a long acting synthetic analogue of vasopressin, which is used to manage variceal bleeding and hepatorenal syndrome.
Jasmohan S. Bajaj +8 more
doaj +1 more source
Incidence and type of adverse events in patients with cirrhosis receiving terlipressin: A systematic review and meta-analysis. [PDF]
Background: Terlipressin has been widely used for various cirrhosis-related complications, but its safety profile remains controversial. Herein, this issue was systematically evaluated.
Shang Y +6 more
europepmc +2 more sources
Protection of cerebral microcirculation, mitochondrial function and electrocortical activity by small-volume resuscitation with terlipressin in a model of haemorrhagic shock [PDF]
Background During early treatment of haemorrhagic shock, cerebral perfusion pressure can be restored by small-volume resuscitation with vasopressors. Whether this therapy is improved with additional fluid remains unknown.
Chisholm, KI +7 more
core +1 more source
Terlipressin Induced Severe Hyponatremia
Terlipressin is a vasopressin analogue used for its vasoconstrictor effect in the treatment of variceal bleeding. Despite its good safety profile compared to vasopressin, some adverse reactions may occur during its use – e.g. hyponatremia.
Martin Šíma +3 more
doaj +1 more source

