Results 51 to 60 of about 7,672 (251)
Docking-based virtual screening of known drugs against murE of Mycobacterium tuberculosis towards repurposing for TB. [PDF]
Repurposing has gained momentum globally and become an alternative avenue for drug discovery because of its better success rate, and reduced cost, time and issues related to safety than the conventional drug discovery process.
Brindha, Sridharan+4 more
core +1 more source
Background Terlipressin, in general, is a vasopressor which acts via V1 receptors. Its infusion elevates mean blood pressure and can reduce bleeding which has a splanchnic origin.
Magdy Mohammed Mahdy+12 more
doaj +1 more source
Cardiovascular drug therapy for human newborn: review of pharmacodynamic data [PDF]
BACKGROUND: Circulatory failure in preterm and term newborn infants is commonly treated with inotropes or vasoactive medications. In this structured literature review, the available data on pharmacodynamic effects of the inotropes adrenaline ...
Bravo, MC+5 more
core +1 more source
Efficacy and Safety of Vasopressin and Terlipressin in Preterm Neonates:A Systematic Review [PDF]
Introduction: The use of arginine vasopressin (AVP) and terlipressin to treat hypotension in preterm neonates is increasing. Our aim was to review the available evidence on the efficacy and safety of AVP and terlipressin for use in preterm neonates ...
Al-Saadi, Abdulrahman+5 more
core +2 more sources
Two-component vasopressor therapy for septic shock
The objective: to investigate the efficacy and safety of terlipressin when it is used as an additional vasopressor in septic shock.Subjects: A single-center, observational, retrospective-prospective study of the efficacy and safety of combined therapy of
A. A. Kochkin+2 more
doaj +1 more source
In a pooled analysis, bradycardia was observed in 6% of terlipressin‐treated patients but rarely required a dose interruption or reduction. Arrhythmia serious adverse event incidences were low and similar in both treatment groups. Routine intensive cardiac monitoring for the detection of arrhythmias may not be necessary during terlipressin ...
Jasmohan S. Bajaj+6 more
wiley +1 more source
Cutaneous Ischaemia Following Terlipressin Therapy for Hepatorenal Syndrome [PDF]
Hepatorenal Syndrome (HRS) is a potentially fatal complication of hepatic failure and portal hypertension. Among the various treatments available including octreotide, midodrine and albumin, the current standard of care for stable patients is ...
Aneesh Basheer+3 more
doaj +1 more source
Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe hepatic encephalopathy [PDF]
There is increasing evidence that terlipressin is useful in patients with cirrhosis and hepatorenal syndrome, but there are no data of its use in patients with acute liver failure (ALF) in whom hepatorenal syndrome is common.
Davies, N.A.+6 more
core
The course of type 1 hepato-renal syndrome post liver transplantation [PDF]
Background. Hepato-renal syndrome (HRS) is a functional form of renal failure that occurs in patients with end-stage liver disease. Previously considered fatal without liver transplantation, treatment with vasoconstrictors and albumin has been ...
Marik, PE, Starzl, TE, Wood, K
core +1 more source
Management Strategies for Refractory Esophageal Varices
ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
wiley +1 more source