Results 101 to 110 of about 4,212,997 (318)
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston+7 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Evolution of cyclic di-GMP signalling on a short and long term time scale. [PDF]
Römling U, Cao LY, Bai FW.
europepmc +1 more source
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
Long Term Time-Lapse Imaging of Geographic Atrophy: A Pilot Study. [PDF]
Paques M+6 more
europepmc +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren+16 more
wiley +1 more source
Long-term time trends in reactivated herpes simplex infections and treatment in Sweden. [PDF]
Lopatko Lindman K+5 more
europepmc +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
Nonlinear heat equation with viscoelastic term: Global existence and blowup in finite time
In this study, we investigate a nonlinear heat equation incorporating both a viscoelastic term and a reaction-diffusion term that depends on space-time variables.
Vu Ngo Tran, Dung Dao Bao
doaj +1 more source
The Evaluation of Two Years of Real-Time Operation of a Short-Term Precipitation Forecasting Procedure (SHARP) [PDF]
A. Bellon, G. L. Austin
openalex +1 more source