Results 21 to 30 of about 2,509 (208)

Attitudes toward end-of-life concerns and associated factors among hospitalized older adults with end-stage cancer in Iran [PDF]

open access: yesNursing and Midwifery Studies
Background: Nurses play a crucial role in delivering end-of-life care; however, patients' attitudes significantly influence the care process. Positive attitudes facilitate patient engagement and understanding of end-of-life options, while negative ...
Salman Rahnama   +3 more
doaj   +1 more source

Ölümcül Hastalığı Olan Çocukların Ailelerinin Güçlendirilmesi

open access: yesSağlık Bilimleri Üniversitesi Hemşirelik Dergisi, 2023
Ailelerin bakım verme rolü kapsamlı ve karmaşıktır. Rutin çocuk bakımına ek olarak ölümcül hastalığı olan çocuğun bakımı bir dizi zorlayıcı duygu, teknik ve beceri içerir.
Fadime Üstüner Top
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Physician-assisted suicide in Italy: where do we stand and where do we want to go?

open access: yesFrontiers in Psychiatry
Physician-assisted suicide (PAS) remains a subject of global debate and ethical controversy, alongside other end-of-life issues such as euthanasia, palliative care, access to health and social care services, and, importantly, patient autonomy.
Emanuela Turillazzi   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Food and fluids in dying patients: some thoughts after the death of a patient

open access: yesSouth African Family Practice, 2004
No abstract available.
D. Cameron
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The meaning of life according to patients with advanced lung cancer: a qualitative study

open access: yesInternational Journal of Qualitative Studies on Health & Well-Being, 2022
Purpose This qualitative study explores the meaning of life and end-of-life coping strategies among patients in China with advanced lung cancer. Methods We conducted in-depth interviews with 21 hospitalized patients with advanced lung cancer and analysed
Jin Mei Zhang   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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