Results 41 to 50 of about 5,027,395 (296)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Food and fluids in dying patients: some thoughts after the death of a patient
South African Family Practice, 2004 No abstract available.
D. Cameron
doaj +1 more source
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2005 In 2001, the Japan Geriatrics Society released its position statement regarding the terminal care of the elderly. In the statement, it is stated as a technical issue that any medical practice implemented in terminal care should warrant its profit to the patient (position 6).
openaire +3 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
, 1984 In the first of two articles on the teaching of terminal care to fourth-year medical students at Queen's University of Belfast, the planner and coordinator of the course describes the objectives and curriculum of the program, which involves the ...
Irwin, W.G.
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Ölümcül Hastalığı Olan Çocukların Ailelerinin Güçlendirilmesi
Sağlık Bilimleri Üniversitesi Hemşirelik Dergisi, 2023 Ailelerin bakım verme rolü kapsamlı ve karmaşıktır. Rutin çocuk bakımına ek olarak ölümcül hastalığı olan çocuğun bakımı bir dizi zorlayıcı duygu, teknik ve beceri içerir.
Fadime Üstüner Top
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2015 The purpose of this paper is less to answer questions than to ask them, and less to define ‘carers’ than to understand who they are. In particular, its purpose is to ask why the label ‘family carer’ may be rejected by some of them, or by particular ...
Care Alliance Ireland
core +1 more source