Results 31 to 40 of about 5,211,884 (256)

Teaching Terminal Care at Queen's University of Belfast: I- Course, Sessional Educational Objectives, and Content

open access: yes, 1984
In the first of two articles on the teaching of terminal care to fourth-year medical students at Queen's University of Belfast, the planner and coordinator of the course describes the objectives and curriculum of the program, which involves the ...
Irwin, W.G.
core   +1 more source

Pharmacological Treatment for Terminal Agitation, Delirium and Anxiety in Frail Older Patients

open access: yesGeriatrics
Context: Psychological distress symptoms in the last days of life often contribute to the overall symptom burden in frail older patients. Good symptom management practices are crucial to ensure high-quality end-of-life care in an aging population, though
Dine A. D. Jennes   +4 more
doaj   +1 more source

Attitudes toward end-of-life concerns and associated factors among hospitalized older adults with end-stage cancer in Iran [PDF]

open access: yesNursing and Midwifery Studies
Background: Nurses play a crucial role in delivering end-of-life care; however, patients' attitudes significantly influence the care process. Positive attitudes facilitate patient engagement and understanding of end-of-life options, while negative ...
Salman Rahnama   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Terminal City To Do List [PDF]

open access: yes, 2001
Listings from Terminal City Weekly including LIVE Biennial events.

core  

Physician-assisted suicide in Italy: where do we stand and where do we want to go?

open access: yesFrontiers in Psychiatry
Physician-assisted suicide (PAS) remains a subject of global debate and ethical controversy, alongside other end-of-life issues such as euthanasia, palliative care, access to health and social care services, and, importantly, patient autonomy.
Emanuela Turillazzi   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Involvement of the family physician in palliative care : an outcome analysis [PDF]

open access: yes, 2004
Includes bibliographical references (leaves 60-63).An evaluation of the degree of involvement of family physicians in the care of patients with terminal illness was conducted. The outcome of this care was correlated with the degree of involvement.
Barnard, Alan J
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Analysis of Home Care Supports Funded by the HSE 2008–2016 [PDF]

open access: yes, 2016
This paper seeks to summarise the situation of publicly funded home care over the period 2008- 2016. Of particular interest is the overall change to the level of resources being directed to home care in the 2016 HSE Service Plan, in particular the actual
Care Alliance Ireland
core  

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