Results 71 to 80 of about 2,011,010 (219)

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu   +4 more
wiley   +1 more source

Le Villi in breve

open access: yes, 2018
Si pubblica un riassunto de motivi principali, estetici e di contenuto, delle Villi, opera teatrale prima di Giacomo ...
Girardi, Michele, Michele Girardi
core  

Human type 2 17beta-hydroxysteroid dehydrogenase mRNA and protein distribution in placental villi at mid and term pregnancy

open access: yesReproductive Biology and Endocrinology, 2007
Background During human pregnancy, the placental villi produces high amounts of estradiol. This steroid is secreted by the syncytium, which is directly in contact with maternal blood.
Plante Julie   +4 more
doaj   +1 more source

Morphological and immunohistochemical features of placenta in postpartum women with hyperprolactinemia history

open access: yesPatologìâ, 2020
Hyperprolactinemia (HP) is a persistent increase in serum prolactin levels, the most typical manifestation of which is a dysfunction of the reproductive system.
T. D. Zadorozhna   +3 more
doaj   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

open access: yesPeriodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon   +6 more
wiley   +1 more source

A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies

open access: yesJournal of Pregnancy, 2014
The vascularity of placental tissue is dependent on various factors of which fetomaternal hypoxia plays a major role. Hypoxia can be of different types and each type influences the vascularity of the villi, especially terminal villi, in its own way.
Anu Priyadharshini Srinivasan   +4 more
doaj   +1 more source

Human placental transfer of xenobiotics in health and disease: New approach methodologies for developmental and reproductive toxicology testing and mathematical modelling

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend New approach methodologies (NAMs) to test the pharmaco‐ and chemicokinetics of compound transfer across the human placental barrier in late pregnancy. Abstract This review addresses an important and timely topic at the intersection of placental biology with respect to barrier transfer kinetics, toxicology and mathematical ...
Paul Brownbill, Eleanor Doman
wiley   +1 more source

Morphometry of Villous Membrane of Placenta at high and low Altitudes

open access: yesJournal of Rawalpindi Medical College, 2009
Background: This cross sectional study was designed to compare the histomorphological characteristics of human placenta at low and high altitudes, with special reference to villous membrane.
Zarmina Saga
doaj  

The effect of intraperitoneal ozone therapy on number of stem villi, intermediate villi, and placenta terminalized villi in Wistar rats with Deoxycorticosterone Acetate (DOCA) induced preeclampsia model

open access: yesIntisari Sains Medis
Background: Preeclampsia, characterized by placental dysfunction, is a significant contributor to maternal and fetal morbidity and mortality. Ozone therapy has demonstrated therapeutic potential in obstetrics, particularly in treating preeclampsia, fetal-placental insufficiency, and reducing fetal growth restriction.
I Nyoman Hariyasa Sanjaya   +4 more
openaire   +1 more source

Physiological and anatomical determinants of placental drug transfer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis   +3 more
wiley   +1 more source

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