Results 61 to 70 of about 13,451 (179)

Morphometry of Villous Membrane of Placenta at high and low Altitudes

open access: yesJournal of Rawalpindi Medical College, 2009
Background: This cross sectional study was designed to compare the histomorphological characteristics of human placenta at low and high altitudes, with special reference to villous membrane.
Zarmina Saga
doaj  

Genetics in Heterotaxy: A Case Series and Literature Review on DNAH9, PKD1L1, MMP21, and GDF1

open access: yesClinical Genetics, EarlyView.
Integrating trio‐based genomic sequencing with detailed clinical evaluation across seven French–Vietnamese heterotaxy cases alongside a review of 108 published patients reveals strong genotype–phenotype correlations. Variants in DNAH9, PKD1L1, MMP21, and GDF1 define a broad spectrum from isolated situs inversus to complex conotruncal heart defects and ...
Thi Bich Tuyen Ho   +23 more
wiley   +1 more source

Stimulation of Ileal Epithelium Growth and Regeneration by Dietary Nucleotide Extracts

open access: yesActa Medica, 2004
The gastrointestinal tract epithelium plays an important role not only in digestion and absorption of nutrients, but also in antigen and pathogen signal translocation toward the gut associated lymphoid tissue.
Dáša Slížová   +4 more
doaj   +1 more source

The effect of intraperitoneal ozone therapy on number of stem villi, intermediate villi, and placenta terminalized villi in Wistar rats with Deoxycorticosterone Acetate (DOCA) induced preeclampsia model

open access: yesIntisari Sains Medis
Background: Preeclampsia, characterized by placental dysfunction, is a significant contributor to maternal and fetal morbidity and mortality. Ozone therapy has demonstrated therapeutic potential in obstetrics, particularly in treating preeclampsia, fetal-placental insufficiency, and reducing fetal growth restriction.
I Nyoman Hariyasa Sanjaya   +4 more
openaire   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

open access: yesCell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar   +5 more
wiley   +1 more source

Stereological Analysis of Mature Human Placenta of Pregnant Women of Different Age

open access: yesBiomolecules & Biomedicine, 2006
The normal placentas, regular pregnancies and deliveries were structurally examined. The aim of this research was to compare the results and to confirm if there were some difference in the structure of placenta related to the age of pregnant women.
Suada Ramić   +2 more
doaj   +1 more source

Immunometabolic Modulation by Low‐Dose Sodium Butyrate: PI3K/Akt/mTOR Signalling Orchestrates Macrophage Polarization to Protect Against Clostridioides difficile Colitis

open access: yesImmunology, EarlyView.
Clostridioides difficile toxins TcdA and TcdB enter intestinal epithelial cells (IECs) via specific receptors, disrupt tight‐junction integrity and activate PI3K/Akt/mTOR signalling, promoting inflammasome assembly and IL‐1β release. Toxin‐induced IEC apoptosis further weakens the epithelial barrier.
Sisi Zhang   +7 more
wiley   +1 more source

Darier disease—A review highlighting new insights from the Darier Disease International Task Force

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz   +49 more
wiley   +1 more source

Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine.

open access: yesPLoS ONE, 2016
The WNT signalling pathway controls many developmental processes and plays a key role in maintenance of intestine renewal and homeostasis. Glycogen Synthase Kinase 3 (GSK3) is an important component of the WNT pathway and is involved in regulating β ...
Fiona Hey   +4 more
doaj   +1 more source

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