Results 81 to 90 of about 13,451 (179)

Oxymatrine improves intestinal epithelial barrier function involving NF-κB-mediated signaling pathway in CCl4-induced cirrhotic rats.

PLoS ONE, 2014
Accumulating evidence suggests that intestinal epithelial barrier dysfunction plays an important role in the pathogenesis of hepatic cirrhosis and its complications such as gastrointestinal injury and hepatic encephalopathy. To date, there is no cure for
Jian-Bo Wen, Fang-Qing Zhu, Wei-Guo Chen, Li-Ping Jiang, Jie Chen, Zhao-Peng Hu, Yong-Jian Huang, Zhi-Wei Zhou, Gui-Liang Wang, Hao Lin, Shu-Feng Zhou   +10 more
doaj   +1 more source

Maternal‐Fetal Administration of Risdiplam Partially Rescues the SMNΔ7 Mouse Model of Spinal Muscular Atrophy

Annals of Neurology, Volume 100, Issue 3, Page 584-599, September 2026.
Objective Spinal muscular atrophy (SMA) is caused by deletions or mutations in the survival motor neuron 1 (SMN1) gene and subsequent reduction in the expression of survival motor neuron (SMN) protein. The disease is characterized by degeneration of α motor neurons and subsequent muscle atrophy.
Emma R. Sutton, Ariane Beauvais, Rebecca Yaworski, Hugh J. McMillan, Rashmi Kothary   +4 more
wiley   +1 more source

Quantitative Investigations of Placental Terminal Villi in Maternal Diabetes Mellitus by Scanning and Transmission Electron Microscopy.

The Tohoku Journal of Experimental Medicine, 1992
The structure of the terminal villi was observed in placentae from non-diabetic mothers and mothers with diabetes mellitus using scanning and transmission electron microscopy. The metabolic condition of maternal diabetes was tightly controlled. In the diabetic group, the diameter of the terminal villi was significantly smaller than in the control group.
HONDA, MASASHI, TOYODA, CHISATO, NAKABAYASHI, MASAO, OMORI, YASUE   +3 more
openaire   +3 more sources

Norethisterone‐Associated Decidual Cast Expulsion Mimicking an Acute Gynecologic Emergency: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Decidual cast is a rare benign condition that may mimic acute gynecologic emergencies. It should be suspected in patients with severe colicky pain followed by sudden relief after tissue expulsion, especially with progestin use such as norethisterone. Accurate diagnosis and histopathology prevent unnecessary surgery.
Tuka Hamasho, Nazaha Al‐hassoun, Nagham Al‐hassoun, Mohammad Al Diab Al Azzawi, Hiba Abdullah, Walid al saleh   +5 more
wiley   +1 more source

Stereological analysis of terminal villi, intervillous space and fibrinoid of adolescent placentas and birth weight of newborns

Medicinski Glasnik, 2019
<p><strong>Aim<br /></strong> To determine stereological structural parameters of the parenchymal part of the placenta, placental weight and volume of adolescent pregnant women and their correlation with newborns' birth weight. <br /><strong>Methods <br /
Sergije Marković, Anis Cerovac, Suad Kunosić, Suada Ramić, Emir Bećirović   +4 more
openaire   +2 more sources

Multiomics analyses revealed the roles of the epithelial–mesenchymal transition and novel early candidate diagnostic biomarkers in neonatal necrotising enterocolitis

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
In infants with necrotising enterocolitis (NEC), excessive inflammation and epithelial cell death promote the epithelial–mesenchymal transition (EMT), leading to damage to intestinal barriers and the translocation of bacteria and toxins. In addition, inflamed epithelia release cytokines to strengthen the inflammatory response.
Xiao‐Chen Liu, Guo‐Bin Liu, Chen Cheng, Jin Zhu, Fei‐Fan Chen, Ying Ji, Yu‐Ni Zhang, Xiao‐Lin Yan, Qing Wang, Xin‐Yu Li, Qing Ai, Yuan Shi, Yu He   +12 more
wiley   +1 more source

Synthetic Food Colorants and Gut Microbiota: A Systematic Review of Preclinical Studies

Food Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT Growing evidence suggests that industrial food processing, including the excess consumption of food additives, might have a negative impact on human health. Despite regulatory safety evaluations, their impact on gut microbiota remains poorly characterized.
Sebastiano Alfio Torrisi, Federica Martina Di Domenico, Gian Marco Leggio, Giuseppe Caruso, Evelyn Frias‐Toral, Nohora Milena Martínez López, Agnieszka Micek, Marialaura Bonaccio, Justyna Godos, Giuseppe Grosso   +9 more
wiley   +1 more source

Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications

Food Frontiers, Volume 7, Issue 5, September 2026.
The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, Volume 3, Issue 3, September 2026.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

Bacterial indole‐3‐butyric acid promotes fish PUFA synthesis

iMetaOmics, Volume 3, Issue 3, September 2026.
Polyunsaturated fatty acids (PUFAs) are essential nutrients in aquatic products, yet the contribution of gut microbiota‐derived metabolites to PUFA biosynthesis remains largely unknown. In this study, a gut‐derived Bacillus strain was identified to enhance PUFA accumulation via indole‐3‐butyric acid (IBA) production.
Ruojing Li, Biao Yuan, Xin Yi, Jieyan Lin, Bi Huang, Ermei Yin, Jiayu Zhou, Qianwen Min, Meiqi Lv, Bo Zhang, Na Zhao   +10 more
wiley   +1 more source